构

In this method, we make use of xml mapping to eliminate name heterogeneity,utilize transformation expression to eliminate unit heterogeneity, make use of transformation function and mapping tables to eliminate precision heterogeneity, data type heterogeneity and the heterogeneity of data expression method.

在该方法中，利用xml映射来消除命名异构；利用转换表达式来消除单位异构；利用转换函数，映射表来消除精度的异构，数据类型异构以及数据表示方法的异构。

The conclusions are as follows:(1) Neologisms in each Huayu region can be classified into two major categories:self-originated and others-originated,among which the new-born words are "absolute new words" and the inherited word are "relative new words",and there are also others-originated elements in the morphemic and sense systems of new words;(2) Variation can be seen in the morpheme,formation,building and sense of new words in Huayu regions,besides individuals of new words;(3) Aggregation of current new words and compound words with one common morpheme and a same construction,together with the aggregation of synonyms and that of different senses in polysemies,reflect the relevance of the systems of new words in Huayu regions in their variation;(4) Regular participation of hinting sense of a formation element in forming and building new words is an important way of producing new sense of morpheme,and an important reason for the current emergence of words with more than one new senses;(5) Compared with ordinary words,the productivity of ways of word formation in forming new words both in general and of a particular class will change and new ways of word formation appear in Huayu regions;(6) The semantic collocation of the verbal morpheme of new verbs in a phrase has a great influence on the location of its structural center,and the complex syntactic behaviors of new verbs are related to the different processes of argument integration;(7) The processes of building new words with the same meaning differ in levels of approaches to motivation cognition,perspectives of motivation cognition,morpheme motivation and morpheme expression,etc.;(8) The lexical interaction in Huayu regions results in lexical subsystem intersections of current new words across two,three and four regions.

本文的主要结论是：(1)各华语区新词均可分为"自源新词"和"他源新词"两大类，其中的新生词和传承词分属"绝对新词"和"相对新词"，新词语的词素、词义系统中也含有他源成分；(2)除词语个体外，华语区新词在词素、构词、造词、词义等方面均体现了某种程度的变异：(3)通用词语聚合、同素同构词聚合、同义异形词聚合与一词多义聚合集中反映了各华语区新词语系统在变异中的关联；(4)构词单位经常提示词义参与构造新词是产生新语素义的重要途径，也是当代多新义词现象的重要成因；(5)相对于一般词语，构词方式在新词语中的总能产性和在某一词类中所体现的能产性都有所变化，华语区也产生了新的构词方式；(6)新动词的动素在短语中的语义搭配对结构核心的位置有很大影响，新动词的复杂句法表现与不同的论元整合过程有关；(7)同义新词造词过程的差异包括理据认知途径、理据认知角度、词素理据和词素表达等不同层面；(8)华语区的词汇互动形成了双区、三区和四区通用新词等词汇子系统交集，作为华语核心，普通话所含纳的通用词语多于各区域变体。

It has been shown that tautomerism has a significant effect on the QSAR modelling, and the models obtained from 1H-indazol tautomeric form always represent higher quality than those from 2H-indazol tautomer, which indicates that 1H-indazol tautomer of the indazolyl urea is probably the active form when binding with the TRPV1 channel protein. It has also been demonstrated that the theoretical descriptors derived from electrostatic potentials on molecular surface together with the GETAWAY descriptors can be well used to express the quantitative structure-activity relationship of indazolyl urea TRPV1 channel antagonists.

结果表明：互变异构对QSAR结果具有一定的影响，采用1H-吲唑异构形式得到的模型，在质量上均高于采用2H-吲唑异构体，预示着1H-吲唑异构体更有可能是吲唑脲类分子的活性异构形式；分子表面静电势参数结合GETAWAY参数可以较好地用于描述TRPV1通道拮抗剂分子结构与其活性间的定量关系。

The costs of abietic acid separating with A amine salt method and B amine salt method were 1/5 and 1/3 of cost separating with di-n-amylamine salt reported in the literature respectively.

同时研究了以酸异构化、高温异构化和微波辅助酸异构化松香制备枞酸含量较高的异构化松香的实验条件，以异构化松香为原料，采用多种方法分离提纯枞酸，得到最佳分离提纯条件。

The crystal structures have been determined by single-crystal X-ray diffraction.Cadmium atoms in compounds 1 and 2 show an eight-coordinated distorted square-antiprismatic geometry and a seven-coordinated distorted pentagonal bipyramidal geometryrespectively. Copper atoms in compounds 3 and 4 show a six-coordinated distorted threeprismatic geometry and a four-coordinated distorted tetrahedral geometry respectively.

所有配合物的晶体结构都通过单晶X-射线衍射确定：配合物1中的镉离子周围显示八配位的扭曲四方反棱柱构型；而配合物2中的镉离子周围显示七配位的扭曲五角双锥构型；配合物3中的铜离子周围显示六配位的扭曲三棱柱构型；配合物4中的铜离子周围显示四配位的扭曲四面体构型；配合物5中的锌离子周围显示六配位的扭曲八面体构型。

The conclusions are as follows:(1) Neologisms in each Huayu region can be classified into two major categories:self-originated and others-originated,among which the new-born words are "absolute new words" and the inherited word are "relative new words",and there are also others-originated elements in the morphemic and sense systems of new words;(2) Variation can be seen in the morpheme,formation,building and sense of new words in Huayu regions,besides individuals of new words;(3) Aggregation of current new words and compound words with one common morpheme and a same construction,together with the aggregation of synonyms and that of different senses in polysemies,reflect the relevance of the systems of new words in Huayu regions in their variation;(4) Regular participation of hinting sense of a formation element in forming and building new words is an important way of producing new sense of morpheme,and an important reason for the current emergence of words with more than one new senses;(5) Compared with ordinary words,the productivity of ways of word formation in forming new words both in general and of a particular class will change and new ways of word formation appear in Huayu regions;(6) The semantic collocation of the verbal morpheme of new verbs in a phrase has a great influence on the location of its structural center,and the complex syntactic behaviors of new verbs are related to the different processes of argument integration;(7) The processes of building new words with the same meaning differ in levels of approaches to motivation cognition,perspectives of motivation cognition,morpheme motivation and morpheme expression,etc.;(8) The lexical interaction in Huayu regions results in lexical subsystem intersections of current new words across two,three and four regions.

本文的主要结论是：(1)各华语区新词均可分为&自源新词&和&他源新词&两大类，其中的新生词和传承词分属&绝对新词&和&相对新词&，新词语的词素、词义系统中也含有他源成分；(2)除词语个体外，华语区新词在词素、构词、造词、词义等方面均体现了某种程度的变异：(3)通用词语聚合、同素同构词聚合、同义异形词聚合与一词多义聚合集中反映了各华语区新词语系统在变异中的关联；(4)构词单位经常提示词义参与构造新词是产生新语素义的重要途径，也是当代多新义词现象的重要成因；(5)相对于一般词语，构词方式在新词语中的总能产性和在某一词类中所体现的能产性都有所变化，华语区也产生了新的构词方式；(6)新动词的动素在短语中的语义搭配对结构核心的位置有很大影响，新动词的复杂句法表现与不同的论元整合过程有关；(7)同义新词造词过程的差异包括理据认知途径、理据认知角度、词素理据和词素表达等不同层面；(8)华语区的词汇互动形成了双区、三区和四区通用新词等词汇子系统交集，作为华语核心，普通话所含纳的通用词语多于各区域变体。

NodD binds to and bends target promoters through anchoring two tandem and individual specific DNA sites. NodD functions as a tetramer, which has a V-shaped main body. Tetrameric NodD is to change its own conformation rather than its oligomeric forms in response to small signal molecules. The specific interaction between each NodD DNA-binding domain and each specific DNA site does not alter itself in spite of naringenin induction, and the induced conformational change is transferred from protein to DNA. Only the DNA conformation incited by induced NodD is competent for RNA polymerase to form the transcriptional open complex. It cannot be excluded that NodD may have protein-to-protein contacts with RNA polymerase, and that the NodD conformational change may also directly contribute to the transcriptional open complex formation. However, the NodD conformational change itself cannot serve as the determinant of the transcriptional molecular switch.

通过研究，我们提出了初步的NodD操纵子激活模型：第一，四聚体是NodD蛋白的功能单位，它通过铆钉两个串联的相对独立的DNA靶位点结合被诱导的启动子；第二，小分子配基的结合是改变NodD四聚体的构象而不是引发不同形式的寡聚体，在我们的模型中，NodD四聚体缩小其V形主体的弯折角，进而缩短其DNA结合功能域的间距；第三，小分子信号的诱导并没有改变NodD的DNA结合域和其DNA靶位点的相互作用，NodD的构象改变由蛋白质经其双铆钉位点传递给DNA；第四，只有诱导状态的NodD激发的DNA构象才能有效地使RNA聚合酶形成转录开放复合物；第五，不排除NodD与RNA聚合酶可能有直接的相互接触位点，不排除NodD构象的改变可能直接有利于RNA聚合酶形成转录开放复合物，但是我们认为NodD构象改变本身不是充当转录激活开关的决定因素。

Careful analyses reveal the connections between the structures of tripeptide and dipeptides or amino acids.Based on the method proposed for dipeptides,a method for finding all important tripeptide conformers utilizing dipeptide and amino acid conformers is put forward.

分析给出了三肽稳定构型和相应的二肽及氨基酸稳定构型间的密切联系，基于二肽构型的寻找方法，发展了一种使用二肽和氨基酸稳定构型来高效寻找三肽稳定构型的方法。

The combined acids , LHZZS,XDZZS and SLZZS, one of four fractions in montan resins from montan waxes from Liaohu, Xundian and Shulan brown coal respectively, were derived by CH 2N 2 to methyl esters and their chemical constituents and structural characteristic were studied on GC-MS.

结果显示，树脂结合酸均以正构烷酸为主要成份，其分布为C1 2 ～C2 8，高含量的正构烷酸集中在低碳数一端，C2 0 含量最高，其次为C1 6 ，而舒兰结合酸中，正构烷酸占绝对优势，且C1 6 为最高含量的化合物；去氢松香酸在每一个样品中含量较低，其它三环二萜酸，如松脂酸、三达松脂酸等异构体或立体异构体含量也非常低；具有五环三萜骨架的酸性物质，在潦浒、舒兰结合酸中比较丰富，其含量超过寻甸结合酸；在低碳数一端，存在着各种支链烷酸及苯甲酸、苯酚及取代物。

The active conformation of protoporphyrinogen IX (substrate of protoporphyrinogen oxidase) has been established using the Distance Comparisons method. In this paper, four different conformational molecules of Protogen IX and crystal molecule of diphenylethers are analyzed by comparing their geometry parameters. The results show the lower energy active conformation from the DISCO model is more reasonable.

我们曾利用距离比较法确定了原卟啉原氧化酶的底物—原卟啉原IX的活性构象，本文从构象分析的角度对4种不同构象的原卟啉原IX分子与二苯醚类分子的晶体学构象进行了几何参数的比较和分析，结果进一步证实了距离比较法所确定的活性构象更为可靠。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。