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We make chloroacetylaion to N-terminal of Asp, and then convert this compound to GD dipeptide by aminolysis. Followed the lipase -catalyzed peptide synthesis of RGD in aqueous water-miscible organic cosolvent is studied. We set up a new efficient reaction method to synthesize RGD tripeptide. The problem that peptide containing polar amino acid can not be synthesized readily in organic solvent was solved. We offer a new experimental proof for PPL-catalyzed peptide synthesis and make a more general analysis for the effect of some factors in theory.

采用氯乙酰基保护天冬氨酸,然后进行氨解生成GD二肽,利用猪胰脂肪酶催化合成RGD三肽,着重解决了亲水氨基酸/肽片段底物的溶解性与合成产率低的问题,建立了一种新的有效合成RGD三肽的反应模型,并探索解决了极性较强的氨基酸的酶促肽合成的问题,对脂肪酶催化合成肽的影响因素从理论上作了较全面的分析,为肽片段的缩合反应提供了一种新思路。

The A and B components remanent magnetization were loaded by goethite and maghemite respectively, the C component remanent magnetization was carried by the magnetite in the sandstones and were loaded conjunctly by the magnetite and hematite in the mudstones and muddy sandstones.

它们的存在并不影响岩石原生剩磁的分离,也不影响原生剩磁信号的稳定性和获得的古地磁数据的可靠性。16个砂岩采点中不能分离出C分量,是由于后生的赤铁矿彻底改变了由磁铁矿携带的原生剩磁组分,在高密度采样的情况下剔除这些采点并不影响古地磁极性柱的构建和解释。

The fatty acid synthetase inhibitor is extracted from fleeceflower vine with polar organic solvent and/or water, preferably 40-60 % concentration ethanol solution.

本发明的脂肪酸合成酶抑制剂是用有机溶剂或水或有机溶剂与水的混合物,从中药首乌藤中萃取出的物质。所述的有机溶剂为极性有机溶剂,其中,优选的是乙醇,最优选的是20%-70%的乙醇,更优选的是40%-60%的乙醇。

Japonica. Brief speculation on the evolutionary trend of the seed-coat micromorphological features of the genus Kadsura is discussed.Cladistic principles and methods have been employed in this study. The morphological characters have been polarized for phylogenetic analysis. Cladograms have been gotten with the related genus Illicium as the outgroup. As a result, a new system of the genus Kadsura has been reconstructed.

整理有关南五味子属植物研究的资料,补充搜集整理近期发表的资料和作者研究所得的数据,采用分支系统学的原理及方法,对本属植物的形态性状进行分析,确定性状极性,以种为基本进化单元,选择近缘且原始的八角属Illicium作为外类群,采用PAUP软件,对本研究得出的性状数据作系统分析,重建南五味子属的系统发育。

Business card printing and membership card making Ink viscosity in business card printing and membership card making faster, rollers and plates after the ink friction heats gets smaller, on the rising of the ambient temperature, the viscosity of ink will drift away, this time using the innovativeink, with the temperature increase, decrease viscosity is referred to as a viscosity index of added value, that is, the viscosity index is a viscosity index of temperature-dependent, for example, at a low temperature solvent oil sludge formation, if you join methylmetacrylate and transfromer monosomic of multi-fault copolymer exclude this.

制卡和会员卡制作油墨的粘度在随制卡和会员卡制作速度的加快时,因墨辊与印版摩擦后油墨温度升高而变小外,当环境温度的上升后,油墨的粘度也会逐渐变小,这种在使用油墨时,随着温度的上升,其粘度下降的行为被称为粘度指数增加值,即粘度指数是表示粘度随温度变化的指标,例如,溶剂油在低温下形成淤浆时,如果加入甲基丙烯酸酯和极性单体的共聚物排除此类故障的发生。

Derivatives of Naphtol AS as the second coupling component were used in mixed coupling and the effect of its added amount on the colour strength,hue,flowability and dispersing extentof pigments was studied.

对含有极性基团(—COOH,— SO3 H)的色酚 AS衍生物的合成及其反应的影响因素进行了研究;合成了 4种新的色酚 AS苯环 3或 4上含有— COOH或— SO3 H基团的衍生物;利用该类衍生物作为第二偶合组分,采用混合偶合工艺对颜料红 57∶ 1进行改性研究,研究了其添加量对改性颜料的着色力、色光、流动性以及在水介质中的分散性的影

"Half-water-hydrolysis"method is used to modify the preaminolysis of phenylenediamine in"step coupling polymerization". First, dehydrochlorination polycondensation between Si-OH and Si-Cl group during polycondensation reaction is employed instead of dehydration reaction between Si-OH groups before, which avoids the disconnection of Si-N bond destreyed by isolated water and improves the H-bonding template effect of the bridged-phenylenediamine.

探索用&半水水解-脱氯化氢缩聚&法对我组过去提出的&全水水解法&的预胺解法加以改进,经&半水水解&得到的含硅羟基和硅氯基的单体再以脱氯化氢代替脱水的方法减少了极性溶剂存在下游离水断裂梯撑模板的硅-氮键的可能性,有效地提高了对苯二胺梯撑中氢键的模板作用。

The invention is characterized in that phthalide of general formula, wherein n and X have the meaning cited in the description, is reacted with nitrogen heterocycles of general formula: H-Z, wherein Z has the meaning cited in the description, or with nitrogen heterocycle metal salts of general formula in the presence of an aprotic polar diluent and optionally in the presence of a basic auxiliary reaction agent.

本发明涉及制备通式的2-杂环基甲基苯甲酸衍生物的新的方法,其中n、X和Z具有说明书中给出的意义,该方法提供高收率和高纯度,其特征是,通式的2-苯并呋喃酮,其中n和x具有说明书中给出的含义,与通式的氮杂环:H-Z,其中Z具有说明书中给出的意义,或与通式的氮杂环的金属盐在质子惰性极性稀释剂中并任选在碱性反应助剂存在下反应。

The two-dimensional structural units (such as silicon-oxygen tetrahedral sheet, octahedral sheet), interlayer space are assembled according to the sphere close packing manner, and the close packing layers parallel to {0001}. There are several mechanisms to release the difference in size while the silicon-oxygen tetrahedral sheet and octahedral sheet assemble the TO and TOT-type structural layers. The two types of structural layers with different interlayer space fitted together in six kinds of assembling modes and formed six kinds of crystal layers. The combinatorics analysis of the two-dimensional structural units revealed that there may be 28 kinds of TOT type interstradified minerals in six kinds of polysomatic assembling modes of interatradified structure. The structural layer is symmetrical for octahedron sheet in the structure of interstratified minerals and shows polarity characteristics.

结果表明,不同二维结构单元体(包括硅氧四面体片、八面体片、层间域的构筑基本符合球体紧密堆积原理,紧密堆积层平行{0001};四面体片与八面体片构筑TO和TOT结构层时采取多种机制消除二者在二维尺寸上的差异;两种模式的结构层与不同类型的层间物组装形成六种组装模式的晶层;并通过二维结构单元体的组合规律的分析,计算出可能存在的28种TOT型间层结构,它们分属于6种间层结构多体性组装模式;间层结构中,结构层对于八面体片是不对称的,并在属性上表现出极性特征;间层矿物的晶层类型可用6种多体性组装模式加以表达。

In this thesis, we find that dlg is indispensible in the establishment of anterior-posterior and dorsal-ventral polarity of drosophila oocyte. Removal of Dlg function from the posterior follicle cells using the FLP/FRT system leads to disruption of oocyte skeleton reconstruction that is elicited by the failure of those posterior cells to differentiate normally in mid-oogenesis. We demonstrate that abnormity of Notch, JAK-STAT and EGFR signal pathway in dlg mutants contributes to this aberrant differentiation. dlg null mutant also blocks the normal differentiation of two groups of anterior follicle cell-stretched cell and centripetal cell, but not border cell, with a lower penetrance. However unlike the result in posterior follicle cells, Notch and JAK-STAT signaling are both undisrupted in all mutant anterior follicle cells, implying other fate determinants may be involved.

我们的研究发现,后端滤泡细胞中的Dlg在果蝇卵子发生中期卵母细胞前后轴和背腹轴建立过程中也是必须的,PFC中dlg完全缺失型突变引起PFC的分化异常,导致卵子发生中期卵母细胞骨架重组异常,Stau、Grk等极性决定蛋白定位错误。dlg突变阻碍了Notch、JAK-STAT、EGFR等调节PFC分化的信号通路的激活。dlg突变的PFC也没有获得前端滤泡细胞命运。dlg突变不影响前端滤泡细胞群中边界细胞的分化,但是在一定程度上影响伸展细胞和向心细胞的分化,并且这种影响不依赖于前端滤泡细胞Notch或JAK-STAT信号激活的异常。

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However, as the name(read-only memory)implies, CD disks cannot be written onorchanged in any way.

然而,正如其名字所指出的那样,CD盘不能写,也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口,替代木托盘,免薰蒸,符合欧盟、北美各国对出口货物包装材料的法令要求;喷涂钢托盘适用于重载上货架之用,托盘表面根据需要制作成平板状、波纹状及间隔形式,满足不同的使用要求。

A single payment file can be uploaded from an ERP system to effect all pan-China RMB payments and overseas payments in all currencies.

付款指令文件可从您的 ERP 系统上传到我们的电子银行系统来只是国内及对海外各种币种付款。