松果体的

Title : Is the Conarium the Third Eye Man Look Through Everything?

松果体是人类洞悉一切的第三只眼吗？

Methods ①In situ hybridization was applied to observe the changes ofhypothalamic CRHmRNA positive cells after PX and melatonin supplementation;②Immunohistochemistry was used to observe the changes of CRH positive cellsin hypothalamus and CRH staining in median eminence of neurohypophysis after PXand melatonin supplementation;③ELISA was applied to detect the changes of CRHconcentration in serum after PX and melatonin supplementation.

①运用CRHmRNA 原位杂交的方法来观察松果体摘除及补充外源性褪黑素后下丘脑室旁核CRHmRNA 阳性细胞的变化；②应用免疫组织化学染色的方法观察松果体摘除及补充外源性褪黑素后下丘脑室旁核CRH 阳性细胞和神经垂体正中隆起CRH 阳性染色的变化；③运用ELISA 法检测松果体摘除及补充褪黑素后血清CRH 浓度的变化。

Methods The pineal capsule of the superficial pineal body of 1.5-month and 12-month old rats was observed under scanning electron microscope.

对1.5月龄和12月龄大鼠松果体浅部，进行松果体囊表面的扫描电镜观察。

The magnetic field is created around the pineal gland, by focusing the mind on the midway point between the pineal gland and the pituitary body.

靠在松果体和脑垂体之间的中点集中意念，松果体周围产生磁场。

The modulation mechanism of the Correspondence between Kidney and Winter is mediated by pineal body which secreat MT seasonally. The pineal body maybe the important medium of regulating relationship between five seasons and five viscera.

"肾应冬"的调控机制是以松果体为中介通过MT的季节性变化而实现的，松果体可能是五季与五脏调控关系机制的重要中介之一。

Objective To study the morphological and functional effect of pinealectomy on CRH neurons in paraventricular nucleus of rat hypothalamus as well as thefunction of melatonin supplementation, enrich the research of the effect of pinealbody and melatonin on hypothalamic-pituitary-adrenal axis,provide theoreticalevidence of the effect of pineal body and melatonin on immune function andimmune-associated disease such as tumor and autoimmune disease.

目的： 研究松果体及其褪黑素对大鼠下丘脑室旁核CRH 神经元形态和功能的影响以及补充褪黑素的作用，丰富松果体及褪黑素对下丘脑——垂体——肾上腺轴影响的形态及功能方面的研究，为进一步揭示松果体及褪黑素对免疫功能以及免疫相关性疾病如肿瘤、自身免疫性疾病等的影响机制提供理论依据。

Objective In order to explore the morphological evidence for the pathway for secretions of pineal body releasing directly into the cerebrospinal fluid. Methods Using the conventional and NaOH-macerational methods for preparing electron microscopic specimens,the pineal bodies and its capsules of adult Japanese monkeys were observed with scanning and transmission electron microscope.

目的 探讨松果体分泌物直接释放入脑脊液途径的形态学依据，方法采用常规及NaOH消蚀法电镜样品制备技术，对成年日本猴松果体及其被囊进行了扫描和透射电镜观察。

The epithelial openings were observed on and among epithelial cells facing the subarachnoid space.The subepithelial connective tissue penetrated the pineal body forming interlobular septum,and separated the pineal body to parenchymal lobules.

在面对蛛网膜下隙的囊上皮细胞和细胞间存在许多上皮孔；上皮下结缔组织伸入松果体形成小叶间隔，将松果体分隔为许多实质小叶。

PX induces the synthesizing and releasing of CRH by CRHneurons increase, activates HPA axis through hypophyseal portal system, thenmelatonin supplementation can partly reverse the abnormality, which indicates pinealbody is one of the key factors to maintain the structural and functional stablity ofneuroendocrine-immune network

松果体摘除导致大鼠下丘脑室旁核CRH 神经元合成和释放CRH 增加，并通过垂体门脉系统激活整条HPA 轴，而补充外源性褪黑素后能在一定程度上逆转上述异常，表明松果体是神经——内分泌——免疫网络的结构和功能的重要稳定因素之一。

Results Tentorial bridging veins of the cerebellum had less interference with the keyhole approach. Galen vein and its tributary could be dissected in security. With this approach, the anatomic structures in the pineal region could be exposed and easy to enter the third ventricle. The operation area could be amplified upward and forward by splitting the tentorium.

结果 小脑天幕面桥静脉对幕下小脑上锁孔入路无影响；Galen静脉系统可被安全解剖；幕下小脑上锁孔手术能充分暴露松果体区的Galen静脉系统、松果体、四叠体等；可经帆间池进入第三脑室；天幕切开能增加向上向前的手术范围。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。