来源

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗(来源：A44B8787C论文网www.abclunwen.com)功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

Immunofluorescence confirmed that sweat glands in normal mice did not present gamma-aminobutyric acid receptor subtype GABAA andα-amino-3-hydroxy-5-methylisoxazole-4-propionic acid/kainic acid subtype of glutamate receptor.Mature mice with reactive sweat glands that declined more than 25% compared to baseline were defined as anhidrotic mice.

免疫组织荧光染色未发现在正常小鼠皮肤组织及汗腺的分泌细胞存在γ-氨基丁酸A型(gamma-aminobutyric acid，GABAA)受体α1亚单位、谷氨酸受体亚型α-氨基羟甲基恶唑丙酸α-amino(来源：Ad1d1BC论文网www.abclunwen.com-3-hydroxy-5-methylisoxazole-4-propionic acid ， AMPA GluR1/2/3/4亚单位和海人酸(kainic acid，KA)受体GluR5/6/7亚单位的表达。

Application of the proposed method can lead to the anticipant experimental results and also decrease the experimental work largely.

该法的应用不仅能达到预期的目的，而且可以大幅度减少所需的试验次数。来源：ABCd7论文b4网www.abclunwen.com

At the same time, as the economic transformation and social improvement, there has been a great change in the life of city, many new fields appear on the scene of Sub-district management, for example,"institution people" becomes "social people"; since China has gone into aging society,aged people have increased a lot; ever-growing number of laid-off workers; more and more floating population; All these new situations apparently increased the amount of service targets and bring pressure to Sub-district management, it is hard to deal with in the old system.

例如，"单位人"转变为"社会人"，增加了街道办事处的管理和服务对象；中国已经进人老龄化社会，各街区的老龄人口显著增多，老年人口的活动空间基本上在家庭所居住的街区，这就增加了街道办事处的工作内容；改革中出现了大量失业下岗人员，需要街道办事处的(来源：A32BC2d论92文网www.abclunwen.com)关心和帮助；随着城乡社会流动加快，城市街区的外来人口越来越多，他们既为街区的发展作出了贡献，也给街区的管理带来了压力。

Artsy people enjoy appreciating and making all kinds of art - painting, drama and music.

我喜欢绘画、来源：考试大音乐和装饰。

Finally we analyze the results of the linear equation by using the modified equation associated with GRP scheme.

进一步地，我们将用modified方程来分析线性方程的数值实(来源：Aad5dBC论文网www.abclunwen.com)验结果。

In Chapter 3, we consider periodic solutions and equilibria at infinity for a generalized Brusselator system.

所以，关于无穷远奇点的一些分析和判断方法也在第二章中给出(来源：bfbfAfbBC论文网www.abclunwen.com)。

Chapter three analyses the author\'s multi-artistic techniques and the point out the key effect of jump of time and space as well as multiply point of view on the presentation of athanasia.

第三章分析了金多元化的艺术表现手法，指出时空跳跃和多角度叙述对表现"永生"主题起到的关键作用。来源：AB12C论文网www.abclunwen.com

Compared with aurum, palladium and platinum as seeds, Silver is much cheaper and lower pollutional and can also activate electroless plating, although it is still rarely investigated.

我们采用激光诱导化学镀技术在聚酰亚(来源：ABC论文1313网www.abclunwen.com)胺薄膜表面上用四种方法选择性沉积金属银作为活化种，然后进行化学镀从而在聚酰亚胺表面上沉积上图形化的铜镀层。

Because of author\'s limited level, there are some shortcomings in the thesis. Everybody is welcome to criticize and correct them.

城中村"的公共权力的配置和运作，对治理主体在"城中村内的组织、管理和调控，来源：Ad0a0B0aC论文网www.abclunwen.com

In the days of sailing vessels the crew were afraid they would be becalmed on the ocean.

在使用帆船的时代，船员们担心他们会因为无风而无法在海洋上航行。

As long as foreign donors pay the PA's salary bill, few expect a new intifada.

只要外国继续为巴权力机构的薪水买单，希望发动新暴动的人便寥寥无几。