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In the brain of adult rat, the positive immunohistochemical product of lSL-l (ISL-l-positive) was mainly located in the neuronal nucleus and found in discrete regions except to brain cortex, such as the Purkinje cell layer and the granular cell layer of cerebellum, the granular cell layer and the pyramidal cell layer of hippocampus, the mitral cell layer, the internal and external plexiform layer, the granular cell layer and the granular cell layer of olfactory bulb and so on, and several nuclei of the hypothalamus, midbrain and pons, such as claustrum, anterior olfactory nucleus, accumbens nucleus, caudate-ptamen, pallidum, substantia nigra, striatum, islands of Callaje, mammillary nucleus, anterior pretactal nucleus, habenular nucleus, amygdaloid nucleus, cuneate nucleus, rubral nucleus, gigantocellular reticular nucleus and so on.

在正常成年大鼠脑中,同源框基因islet-1表达产物(ISL-1)免疫组织化学阳性物质广泛分布于除大脑皮层外的神经细胞的细胞核内,ISL-1阳性神经元密集分布于小脑Purkinje细胞层和颗粒细胞层、海马的颗粒细胞层和锥体细胞层、嗅球的内丛层、外丛层、颗粒细胞层及僧帽细胞层等,另外在丘脑、中脑和桥脑的一些重要神经元核团均有分布,如,屏状核、前嗅核、伏核、尾壳核、苍白球、黑质、纹状体、Calleja岛、乳头体核、前顶盖前核、缰核、杏仁核、楔束核、红核网状巨细胞核等。

Its hydrophilic groups is the inside carbonyl and amine base, and its lipophilic groups is the inside hydrocarbon chain and outer methyl. PAMAM of integral generation basically has not the surface activity. Its reason is that its outer groups is acylamino groups having very strong hydrophilicity so as not to reduce the surface tension of water. PAMAM different from traditional surfactant, have not critical micelle concentration, and exist in the form of "unimolecule micelle" in water.

结果表明:半代的PAMAM水溶液的表面活性与其分子具有两亲结构有关,亲水基团是内部的羰基和胺基,亲油基团是内部的碳氢链和外层的甲基;整代的PAMAM水溶液基本上没有表面活性,其原因是其最外层基团是酰胺基,亲水性很强,不能降低水的表面张力;树状大分子与传统的表面活性剂不同,不存在临界胶束浓度,在水中是以&单分子胶束&形式存在。

CuS and CdS nano-particulate films were obtained with these two methods, and some interesting phenomena were observed: under the Gibbs film formed by CTAB, CuS nano-rods were obtained at the oil/water interface, and disklike aggregates of CdS nano-crystals were obtained at both the air/water and oil/water interfaces; under the Langmuir film formed by NaAOT at air/water interface, disk-like aggregates of CdS were also obtained.

利用此两种反应技术,制备了CuS和CdS颗粒膜,并研究了它们的一些光电性质;在Gibbs膜下,得到了棒状CuS纳米晶。由发现的表面活性剂形成的带状物,提出棒状CuS晶体是以带状聚集体为模板形成的;在液-液、气-液界面Gibbs膜下反应中,发现CdS纳米颗粒的盘状聚集体的形成,这是由于表面活性剂在界面上形成的二维胶束而造成的;在气-液界面上Langmuir下的反应中,也发现CdS盘状晶体的生成。

The microstructure of MDF and MDF tested were studied. The results showed that the fibers in MDF are arranged randomly. Some of them arranged separately, most of them arranged in bundles. There are many blind holes between the fiber cells in MDF. The damage of MDF's compressive creep is the result of new cranny occuring, spreading and the combination of old cranny. In the repressing process, besides the pressure, heat is also the main factor on the damage of MDF, which can accelerate the adhension layer to deteriorate and lead to the gule strength decreasing.

结果表明:MDF的纤维排列无规则,纤维排列形态除少量纤维呈单根状外,大量的纤维以纤维束的形态排列;纤维之间存在许多大小不等的孔洞,呈不贯通状;MDF蠕变损伤是不断萌生新的裂隙并扩展和合并原有裂隙的结果;MDF二次加工过程中,除了压力是破坏MDF结构的主要因素外,加热温度使MDF胶层老化,胶合强度下降,也是破坏MDF结构的主要因素;MDF的破坏形态除了有纤维拉断外,还有纤维拔出和胶粘剂脱落。

The micelle granules were accumulated in the guttate structure. Both liquid crystal phase and isotropic phase coexisted here. With the volatilization of solvent, the structures can change from disc or hexagon to cube with the variation of environment and interior reciprocity.

结果表明,在该薄膜中有被冻结的液晶滴状结构,随着溶剂的挥发,膜体系内氢键的种类和数目发生改变,壳聚糖胶束颗粒聚集成圆盘或六角状,体现为同心环堆积,一定时间后转变为立方环状结构。

Results Histologically, the tumor was composed of mildly cellular benign-appearing spindle-shaped cells and bands of hyalinized collagen in varying proportions from area to area, and a typical patternless archite...

结果镜下见肿瘤组织由不同比例的纤维母细胞和胶原构成,纤维母细胞分化良好,形态多样,散乱穿梭于胶原蛋白束之间或环绕在玻璃样变的血管周围,伴有局灶性致密区域;胶原成分发生玻璃样变,局部呈轮辐状或瘢痕状排列。

Also, CdWO4 nanowires and BaWO4 nanoparticless with different shapes, such as wire-like, rod-like, and hollow spherical, were prepared in different microemulsion systems using octane as oil, undecylenic acid and/or dodecylamine as surfactants.

此外,在十二胺、十一烯酸和正辛烷组成的反胶束乳状液体系中合成了不同形貌的BaWO4纳米粒子及丝状CdWO4纳米粒子。

A 46-year-old man presented with a gradually growing nodule on the left dorsal foot, which had been present for over 10 years. In the beginning, the lesion was treated as a keloid. Because of poor response to treatment, biopsy was arranged. Sections showed a dermal tumor composed of numerous foamy cells, hyalinized wiry collagen, spindle cells and entrapped collagen. The foamy cells were positive for KP1(CD68) and negative for S-100 protein and HMB-45. The histological and immunohistochemical results were consistent with the diagnosis of lipidized fibrous histiocytoma.

一位46岁男性从十年前开始於左足背上出现一个逐渐长大之结节,一开始被当作蟹足肿给予治疗,因为对治疗的反应不好,故安排了切片检查,病理显示一个由大量泡沫状细胞,坚硬而透明之胶原纤维,梭状细胞,胶原纤维束所构成的真皮肿瘤,免疫组织化学染色显示KP1(CD68)阳性,S-100 protein与HMB45阴性,综合病理与免疫组织化学染色结果,诊断为脂肪性纤维组织细胞瘤。

Results GFAP-immunoreactive cells in the control mice were observed mainly within hippocampal formation, piriform, entorhinal cortex, septum, striatum, amygdaloid nucleus, subcortical white matter, as well as in the main fiber tracts.

结果:PBS注射的对照组动物脑内GFAP阳性的星形胶质细胞主要分布于海马、梨状皮质、内嗅皮质、隔区、纹状体、杏仁核及主要的纤维束。

The morphology and structure of reconstructed tissue was detected by microscope and scanning electron microscope.Results:(1) Compared with the control group, the cellular proportion of laminin group increased in 62 ~M phase, and decreased in Go~Gi phase significantly. As shown by the microscope, the cells of control group were in low density. The cells in mass connected tightly. The microfilament appeared reticular formation. The nucleus were the same in size. The cells of laminin group were in high density and put out so many lamellipodia, filopodia, which connected with the surrounding cells. The microfilament increased, elongated, and changed from reticulodromous to sarciniform, which reached to the pseudopods. The nucleus were different in size .(2) As shown by the inverted microscope and the cell growth curve, comparing with the controlgroup, cells of each test group increased evidently. The cellular proportion of each test group increased in S phase and G2 ~M phase, and decreased in Go~Gi phase significantly, but there was no considerable interations between LN and EGF;(3) As shown by the morphological observations, the cultured cat corneal endothelial cells formed an integrated membrane, and attached to the Descemets membrane closely, which was similar to the natural tissue. The cells connected tightly to each other, and some of them arranged in hexagon approximately.

结果:(1)层粘连蛋白组处于G_2~M期细胞比例较对照组显著提高,Go~G_1期细胞比例显著下降,提示层粘连蛋白促进内皮细胞DNA合成,及细胞分裂增殖;光镜下,对照组细胞分布成团状,细胞密度较低,细胞间连接紧密,细胞内微丝结成网状,细胞核大小一致;与对照组相比,层粘连蛋白组细胞生长旺盛,细胞密度高,向周边伸出大量板状及丝状伪足,细胞内微丝增多、拉长、集结成束,伸入伪足中,细胞核形状大小不一致;(2)倒置显微镜观察及细胞生长曲线显示,各组细胞数目随时间增加而明显增多,各实验组较对照组增生显著,EGF和LN联合应用组各时间点细胞数目最高;实验组处于S期和G_2~M期细胞数目增加,Go~G_1期细胞数目减少;提示EGF、LN单独及联合应用均可促进细胞增殖,但尚不能认为二者有交互作用;(3)倒置显微镜下,组织培养的猫角膜内皮细胞排列成密集的单层,细胞间连接紧密;组织学观察发现,培养的猫角膜内皮细胞形成完整的内皮层,贴附于脱水基质的后弹力膜上,与正常的角膜内皮组织结构相似;扫描电镜下,组织培养的猫角膜内皮细胞间紧密镶嵌排列,可见某些细胞呈近似六边形排列,细胞大小不甚一致,胞核清晰。

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