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Aerobe bacteria overgrowth and decreased lactobacillus of the small intestine will strengthen the pathogenicity of gut flora and disturb the absorption of nutrient, resulting in many symptoms related with alcohol. And these changes are result from complex factors not direct effect of acohol.

结论长期饮酒后小肠需氧菌过长、乳酸杆菌减少,增强了肠道细菌的致病性,影响肠腔营养物质的吸收,导致酒精相关的肠道病变的发生,且这种改变是诸多因素共同造成的而非酒精直接作用的结果。

Results The positive detecting rate of aerobe bottle against aerobe was 100%, Sensitivity was 10 CFU/ml. The positive detecting of anaerobe bottle against anaerobe was 100%, Sensitivity against peptococcus niger, Peptostreptococcus anerobius, bacteroides fragilis was 10 CFU/ml, 100 CFU/ml, 1000 CFU/ml, respectively.

结果 需氧瓶对需氧菌的阳性检测率为100%,检测敏感性为10 CFU/ml;厌氧瓶对厌氧菌的阳性检测率为100%,对黑色消化球菌、厌氧消化链球菌和脆弱类杆菌的检测敏感性分别为10 CFU/ml、100 CFU/ml和1 000 CFU/ml;厌氧瓶对兼性厌氧菌的阳性检测率为100%,检测敏感性为10 CFU/ml。

It is recommended that maintenance treatment should be individual in clinical experiences.It is reasonable to choose the different maintenance therapy plan according to ulcer cicatrization quality under endoscope and the helicobacter pylori situation respectively,which not only can control the recurrence of peptic ulcer effectively,but also can reduce the patient′s economic burden,achieves treatment individuation,and instructs the patients with correct consolidated treatment.

临床上推荐维持治疗个体化,根据内镜下消化性溃疡瘢痕情况和幽门螺杆菌感染情况分别选择不同方案的维持治疗是较合理的,既可有效地控制溃疡复发,又可减轻患者的经济负担,真正做到治疗个体化,指导患者溃疡愈合后正确的巩固治疗。

BACKGROUND: The mechanism of spasmodic dysphonia is still unclear and lacks of confirmed diagnostic standards. Limited reports on the treatment mainly focused on botulinum toxin infiltration; recurrent laryngeal nerve section, and voice training, amongst which voice training has been considered as one of the ideal complementary therapeutic means for SD because of less side effects and complications.

背景:目前痉挛性发声障碍病因不明,缺乏统一明确的诊断标准,故治疗较为困难,关于该病的治疗有限的报道主要是喉部肉毒杆菌毒素注射,喉返神经切断,发声语言训练等,其中后一种方法无副作用及并发症,是较为理想的治疗及辅助治疗手段之一。

Gravid An. sinensis demonstrated significant negative taxis towards bacteria A4 and Aeromonas sp., as well as slight taxis to Enterobacter sp., implying that the three bacteria were not the dietary preference for An. sinensis. However, in light of the possibility of their stable colonization into mosquito's guts, these strains may serve as the host cells of larvicide genes and transgenic anopheline antimalarial genes.

中华按蚊产卵时对A4菌和气单胞菌具有明显的负趋性,而对肠杆菌仅具有微弱的趋向性,推测这3种细菌可能不是中华按蚊食物的优先选择,但具有在蚊中肠内较为稳定存活的可能性,因此更适合于作为蚊幼生物杀虫基因的寄主细胞和仿转基因按蚊抗疟基因的寄主细胞被应用。

Many studies have reported that Klebsiella pneumoniae is associated with ankylosing spondylitis but the mechanism of pathogenesis is remained unclear. The endoplasmic reticulum stress would be induced upon exposure of decapsulated KP in HLA-B27 expression B lymphoblast CA46 cells and non-HLA-B27 expression U937 monocytes. Our previous studies demonstrated that decapsulated KP could up-regulate BiP/Grp78 and calreticulin expressions in a dose- and time-dependent manner. We screen more than 60 kinds of traditional herbs and bioactivity agents and we found that berberine,taurine,extracts of Andrographis paniculata Nees.

许多研究指出克雷伯氏肺炎杆菌和僵直性脊椎炎有相当的关系,但是致病机制仍然不是很清楚,因此我们使用去荚膜克雷伯氏肺炎菌来诱发表现HLA-B27的CA46 B淋巴球母细胞、不含HLA-B27的U937单核球细胞可以产生内质网压力,我们先前的实验指出,随著剂量增加,去荚膜克雷伯菌能够过度调控内质网压力指标蛋白质BiP和Calreticulin表现增加。

Helicobacter pylori is a spiral-shaped,Gram-negative bacterium,which is the main causes resulting in gastroduodenal ulcer and chronic reactiveness gastritis and has a close relationship with MALLT and gastric cancer.

幽门螺杆菌是一种存在于人类胃黏膜的G-的螺旋形细菌,是胃十二指肠溃疡、慢性活动性胃炎的主要病因,并与黏膜相关性淋巴组织淋巴瘤及胃癌的关系密切。

Helicobacter pylon, a kind of gram-negative bacteria which colonizes in the huanin stomach, has been identified as a major pathogen associated with the development of chronic gastritis and gastroduodenal ulcer disease as well as gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. The infection rate of Hp is very high.

幽门螺杆菌(Helicobacter pylori,简称Hp)是定植于人胃部的一种革兰氏阴性菌,它与慢性胃炎、消化性溃疡、粘膜相关淋巴样组织性淋巴瘤、胃癌等疾病的发生密切相关,它的感染率高,并且因为人免疫系统无法根除而长期生存于人的胃部。

A new strain of Brevibacterium casei with high nitrilase activity was screened from natural environment and could convert nitrile into carboxylic acid.

从自然源筛选到的一株腈水解酶产生菌乳酪短杆菌,能够高选择性地将腈转化为羧酸,初步研究了该菌株所产的腈水解酶在游离细胞形态下的催化特性,包括热稳定性、pH稳定性、金属离子和添加剂的作用、溶剂耐受性及底物特异性等。

Result A strain of Pseudomonas cepacia was detected in 1.6% compound quaternary ammonium disinfectant before application. The amount of the germ was 1.21×105cfu/ml. The strain had the similar resistance to chlorine-containing disinfectants and glutaraldehyde compared with Staphy aureus. The contaminated disinfectant could still thoroughly destroy the antigenicity of HBsAg with 60min's contact after diluted for 5-20 times.

结果 该洋葱假单胞菌对氯和戊二醛的抗力与大肠杆菌和金黄色葡萄球菌接近,污染样液除菌后1 000倍稀释对大肠杆菌和金黄色葡萄球菌仍有较好的杀菌效果,20倍稀释可完全破坏HBsAg抗原性,和抑制枯草杆菌黑色变种芽胞的生长,1 600倍稀释可抑制白色念珠菌生长,而原液则不能抑制分离菌株的生长。

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