杂合的

NKCCl(superscript -/-) mice were deaf and demonstrated difficulties in maintaining their balance. NKCC1 mice exhibited a marked atrophy of the stria vascularis, contraction of the endolymphatic compartments and collapse. CONCLUSION: NKCCl channel plays a critical role in potassium homeostasis of endolymph in the inner car.

光镜下NKCCl野生型小鼠和NKCCl杂合子小鼠的耳蜗解剖结构无明显异常；NKCCl突变纯合子小鼠的耳蜗出现前庭膜塌陷、内淋巴腔缩小而致中阶完全消失，并有血管纹萎缩、Corti器缺失、螺旋神经节萎缩；且球囊和椭圆囊膜迷路失去正常结构并出现塌陷等病理改变。

The average length of the homozygotefragments was 15.4cM, while it was 12.29cM of the heterozygote fragments.

纯合导入片段的长度平均为15.4cM，杂合导入片段的长度为12.29cM。

Results Among 54 WD patients, 36 were found to carry Arg778leu mutation, among whom 15 were homozygote, 21 were heterozygote, the frequency of this mutation was 47.2%. Of 46 patients with hepatic damage, 36 were found to have the mutation of Arg778Leu, among whom 34 were found to have Leu770Leu polymorphism simultaneously.

结果 54例Wilson病患者中36例存在Arg778Leu基因突变，15例为纯合型，21例为杂合型，Arg778Leu等位基因突变频率为47.2 ％；46例伴肝损害的患者中33例存在ATP7B基因外显子8的Arg778Leu突变；36例Arg778Leu突变者中34例同时伴有Leu770Leu多态性。

There were totally 22 alleles of these microsatellite loci, and the number of alleles per locus ranged from 2 to 6. The average homozygosity, average polymorphism information content and average heterozygosity was 41.67%, 0.488 and 0.5833, respectively.

对这6个位点的扩增产物进行分析，结果显示：6个位点共检测到22个等位基因，每个位点的等位基因数从2个到6个不等；平均基因纯合率为41.67%，平均多态信息含量为0.488，平均杂合度为0.5833。

Result The average homozygosity of 5 microsatellite loci in the population of small-tailed Han sheep was 0.37 and the average heterozygosity was 0.63, which indicated that microsatellite loci in small-tailed Han sheep had the variation to certain degree.

结果］5个微卫星位点在小尾寒羊群体中的平均纯合度为0.37，平均杂合度为0.63，说明小尾寒羊微卫星位点存在一定程度的变异。

Mouse models of this genetic defect have been unsatisfactory because homozygote null animals die early in development and heterozygotes do not exhibit a cardiac phenotype.

这种遗传缺陷的小鼠模型并不能令人满意，因为纯合子缺陷动物在发育早期就会死亡，而杂合子又不能显示心脏表型。

Chapter Four explains the importance of hybridity in relation to the characters\' identities.

第四章通过对杂合性和人物身份关系的讨论，进而分析沙林·西奈身份的杂糅性，并指出由沙林之子阿当所代表的"第三空间"。

After 6 to 7 days of culture, Eleven ES cell lines were selected and explanted. At last we obtained 4,3,4 and 3 ES cell lines separately. One of the B6C3F_1×B6D2F_1 ES cell lines was selected to future study its competent for germline transmission.We founded the ES cell line has normal karyotype on the chromosome analyse.In teratoma experiment by injected ESCs into C57 mices inguen, we gained teratoma contained cells come from all three embryonic germ layers.

选择一株具有高度杂合背景的B6C3F_1×B6D2F_1 ES细胞系进行核型分析、畸胎瘤实验后与ICR品系2n胚胎构建嵌合体并得到具有生殖系传递能力的嵌合体小鼠，证明此细胞系具有生殖系嵌合能力。

Results The vaccinal vestige, BCO immunization and familial traits were the risk factors of tuberculosis. Frequency of wildness, mutant heterozygote and homozygote of MBP-54 was difference in cases and controls.

MBP-54位点野生型、突变型杂合子、突变型纯合子3种基因型在病例组和对照组中的分布频率不同。

Methods: The human Fd repertories genes were amplified by RT-PCR from PBMC of hepatoma patients, and cloned into the vector pComb3X with chimeric L chain to construct the human-mouse hybrid Fab phage library.

利用RT-PCR自肝癌患者外周血淋巴细胞中扩增全套人抗体重链Fd基因片段，克隆入含嵌合L链的展示载体pComb3X，建立人－鼠杂合Fab噬菌体抗体库。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。