杂合性

Anaphase bridges were used as indicators of inversion heterozygosity.

用后期桥作为倒位杂合子性的指标。

It is suggested that it is better to indicate the variability within breeds by average heterozygosity based on microsatellite polymorphisms, which showed high polymorphisms and codominant inheritance of the markers, where as differences between populations and even specific characteristics with in a population are reffected clearly and directly by RAPD.

由于微卫星标记多态性程度高且等显性遗传，因而通过它计算杂合度可以较好地反映群体内的变异；RAPD则在反映群体间的区别甚至某一群体的特征时可提供明确而直接的信息。

Gene mutations were detected in 25 patients and a 18-year-old girl among 16 families. Trinucleotide repeats of CAG were 73～79. The fragments of abnormal alleles were 380～402bp, and all patients were heterozygous. The copy numbers of normal alleles were 18～40, fragments from 202～270bp. SCV reduction was much obvious compared to MCV, MCV and SCV in lower limb ?ere much more slow than that in upper's. BAEP, VEP were also delayed in latency. The anticipation in parental sex bias were much more obvioius than that in matental's. Cerebellar ataxia was most severe, the next were dysarthria and bulging eyes. Amytrophy was seen only in bed ridden patients. Cerebellar atrophy was more severe than brain stem, cord atrophy was n't observed in all MJD.

结果检出10个家系25例病人及1例症状前18岁女孩有MJD基因突变，CAG三核苷酸重复73～79次，异常等位基因片段长380～402bp，均为杂合子；正常人CAG三核苷酸重复18～40次，等位片段长200～270bp，电生理发现MJD的SCV减慢比MCV明显，而下肢的MCV、SCV又较上肢明显，BAEP、VEP均有不同程度的潜伏期延长或波的异常；MJD的父亲遗传早于母亲，进展也较块，临床以小脑性共济失调为突出症状，其次为构音障碍、突眼等，肌肉萎缩仅见于晚期病人；MRI示小脑萎缩较明显，脑干萎缩并不严重，未见明显的颈髓萎缩。

Detection of HLA-B27 and its related B antigens was useful to investigate the heterozygosis of these B loci and the cross-reactivity of their antigens.

检测HLA-B27及其相关B位点抗原的频度有助于分析这些位点的杂合及其抗原的交叉反应性的特点。

The frequency of TNFβ+252 locus GA heterozygote may be related to the prognosis of SARS.

结论TNFβ+252位点的基因多态性与严重急性呼吸综合征发病易感性无关，但TNFβ+252位点G/A杂合子频率与严重急性呼吸综合征的预后有关。

All loci detected in the study showed polymorphism and the number of alleles ranged from 2 to 22 in total population.

在所检测的4个群体中，各群体均有较高的多态性，其杂合度都超过了0.55，各位点等位基因的数目为2~22。

Female mosaicism of the X chromosome has major implications for human health and disease and is the leading cause of female protection from X-linked genetic disorders.

女性作为X染色体的杂合子在人类的健康与疾病中及重要作用，并可避免X连锁遗产性疾病在女性中发生。

This can be accomplished when an animal is produced in which the germ cells, which produce sperm or egg, are derived from the heterozygous recombinant cells.

当产生这只动物的性细胞是来自于杂合的重组细胞时，就有可能得到这样的动物。

VWF gene is one of the most polymorphism genes. There is a lot of allele in 40th intron of vWF gene, and the heterozygous rate is higher.

vWF基因是人类最具多态性的基因之一。vWF基因40号内含子中的VNTR存在多种等位基因，有较高的杂合频率。

Results A Tru9 I restriction fragment length polymorphism in the 5′ flanking region of the FⅨ gene was first identified in Guangxi.

结果 首次在广西人群中发现FⅨ基因5′侧翼698位核苷酸存在Tru9 I多态性，该多态性由83 bp/58 bp+25 bp组成，二者的基因频率在受检的180个FⅨ基因中，分别为0.622和0.378，女性杂合子频率为0.473。

For a big chunk of credit-card losses; the number of filings (and thus charge-off rates) would be rising again, whether

年美国个人破产法的一个改动使得破产登记急速下降，而后引起了信用卡大规模的亏损。

Eph. 4:23 And that you be renewed in the spirit of your mind

弗四23 而在你们心思的灵里得以更新