杀细胞的

The myocardial enzyme, liver duty enzyme, kidney duty enzyme, amylopsin and blood sugar in serum were detected, the results showed that CK, CK-MB, ALT and AMY had different extent changing characteristic, but CRE and BUN no obviously change.

分别于接种病毒后15天和30天剖杀猕猴进行病理学组织学观察，其病变以病毒性心肌炎、间质性肾炎、神经系统的非化脓性炎症及肝脏汇管区有细胞增生性反应为主要特征，其他组织器官也有不同程度的病理变化。

The assay of DPPH free radical clean test best is Cissus pteroclada, it has over 95%, in anti-liver lipid peroxidation assay, the best is Ampelopsis cantoniensis, it has over 95% too, and Ampelopsis Japonica has well effect on killing human breast cancer cells MCF-7 but have no effect about anti-oxidation.

抗肝脂质过氧化试验中以广东山葡萄最好，其抑制率有95%以上。白蘝对於抗氧化虽然无特别效用，但在人类乳癌细胞株MCF-7毒杀试验上有很好的成效其抑制细胞生长率为95%以上。

Gravid An. sinensis demonstrated significant negative taxis towards bacteria A4 and Aeromonas sp., as well as slight taxis to Enterobacter sp., implying that the three bacteria were not the dietary preference for An. sinensis. However, in light of the possibility of their stable colonization into mosquito's guts, these strains may serve as the host cells of larvicide genes and transgenic anopheline antimalarial genes.

中华按蚊产卵时对A4菌和气单胞菌具有明显的负趋性，而对肠杆菌仅具有微弱的趋向性，推测这3种细菌可能不是中华按蚊食物的优先选择，但具有在蚊中肠内较为稳定存活的可能性，因此更适合于作为蚊幼生物杀虫基因的寄主细胞和仿转基因按蚊抗疟基因的寄主细胞被应用。

This is the case when only a few cells are hit, and if they are killed outright.

当只有一些细胞是击中的时候，这是情形，而且如果他们率直地被杀。

For most viruses,there is aneed for antimicrobials that target unique viral molecular properties.Acycloviris one such drug.It is activated into ahuman herpesvirusDNA polymerase inhibitor exclusively by HHV kinases and,thus,does not suppress other viruses.Here,we show that ACV suppresses HIV-1in HHV-coinfected human tissues,but not in HHV-free tissue or cell cultures.However,addition of HHV-6-infected cells renders these cultures sensitive to anti-HIV ACV activity.We hypothesized that such HIV suppression requires ACV phosphorylation by HHV kinases.Indeed,an ACV monophosphorylated prodrug bypasses the HHV requirement for HIV suppression.Furthermore,phosphorylated ACV directly inhibits HIV-1reverse transcriptase,terminating DNA chain elongation,and can trap RT at the termination site.These data suggest that ACV anti-HIV-1activity may contribute to the response of HIV/HHV-coinfected patients to ACV treatment and could guide strategies for the development of new HIV-1RT inhibitors.

对大多数病毒而言，都需要有针对其分子特性的靶向杀毒剂阿昔洛韦就是这样一种靶向药物在人疱疹病毒酶的特定作用下，阿昔洛韦被激活成为人疱疹病毒DNA聚合酶抑制剂，因此不能再抑制其它的病毒我们的研究发现阿昔洛韦在共感染人疱疹病毒的组织中可以抑制HIV-1，但在无人疱疹病毒感染的组织或细胞中无此作用然而，加入人疱疹病毒-6感染的细胞却使得其对抗HIV的阿昔洛韦变得敏感我们推测这种抑制作用依赖于人疱疹病毒酶导致的阿昔洛韦磷酸化实际上，单磷酸化的阿昔洛韦前体药物无需人疱疹病毒的参与即可抑制HIV此外，磷酸化的阿昔洛韦能直接抑制HIV-1逆转录酶，将其阻止在终止位点，从而终止DNA链的延长这些结果提示阿昔洛韦的抗HIV-1活性决定了艾滋病病毒/人疱疹病毒共感染的患者对阿昔洛韦的治疗反应，也有助于开发新的HIV-1逆转录酶抑制剂

Water extract of P. lobata was effective and its minimal concentration that inhibited 50% of the cytopathic effect (IC50) was 0.028 μg/mL.

在病毒感染前投与(p.0001)，在病毒感染时投与(p.0001)，或在病毒感染之后投与(p.0001)，皆能显示葛根热水萃取物有效抑制肠病毒71型感染造成的细胞毒杀作用。

Compared with those in control group,the number of positive immunoreactivity cell in RSR and intestine increased and its intensity of immunoreactivity enhanced obviously after rabbit was infected with Pasteurella multocida.

免疫组织化学观察发现，产抗菌肽细胞在兔圆小囊的黏膜上皮、圆顶上皮以及淋巴组织的滤泡生发中心、圆顶区和帽区均有分布；在兔感染多杀性巴氏杆菌后，圆小囊及其他肠道组织中的抗菌肽免疫组织化学阳性细胞数量明显增多，阳性反应增强。

Foreign gene could destroy larvas mid-intestine, and reduce its appetite. Observation by microscope showed that the gaps between mid-intestine cells was extended in treated larvae, and the nucleus were destroyed, the gap between peritrophic membrane and mid-intestine cells was appeared, parts of peritrophic membrane was broken off from mid-intestine cells.

外源基因对舞毒蛾幼虫的杀虫机理在于破坏幼虫的中肠组织，影响幼虫的取食，使幼虫取食量减少，甚至终止取食；中肠细胞间隙增大，细胞核遭受破坏；围食膜与中肠细胞之间出现空隙，甚至脱落，围食膜不再完整；中肠组织脱落，成为一个严重变形的残架。

Methods Pregnant rats were gavaged castor oil-diet in 18 and 19 days of gestation. At the time of death, blood of portal and peripheral veins, intestinal mucosa, amnion, amniotic cells and placenta were collected, and the tissues were cultured in the presences of ricinoleic acid or indomethacin.

将妊娠18天的Wistar大鼠分实验组和对照组各8只，实验组大鼠每天两次灌服引产餐，灌服4次后剖杀大鼠，收集门静脉、末梢血，胎盘、羊膜组织及制备羊膜细胞进行体外培养。

Objective To investigate genetic toxicity of three persistent organic pollutants,including aroclor1254,DDT and Toxaphene,using human derived hepatoma(HepG2)cells/in vitro micronucleus assay.

目的用人肝肿瘤细胞Hep G2/体外微核试验检测3种持久性有机污染物Aroclor1254、毒杀芬和滴滴涕的遗传毒性。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。