机制

AIM: To isolate bioactive secondary metabolites from the fruits of Schisandra rebriflora Rehd. et. Wils and study their effects on HIV-1 infectivity. METHODS: Inhibition of syncytia formation, HIV-1 reverse transcriptase and protease, protection of HIV-1 infected cells, level of HIV-1 p24 antigen,blockage of fusion were detected. RESULTS: A lignan compound, named rubrifloralignan A, was first isolated as a natural product with modest inhibition effects on syncytium formation and HIV- 1 replication and could protect HIV-1 infected cells with weak inhibition effects on fusion and RT, but it showed no effects on the replication of HIV-1 chronic H9 and PR. CONCLUSION: Rubrifloralignan A is an efficient anti-HIV-1 product with effect on early stage of HIV-1 replication.

目的：从红花五味子果实中寻找活性代谢产物，研究其抗HIV—1活性和作用机制方法：通过合胞体抑制、HIV-1感染细胞保护、HIV—1p24抗原测定、融合阻断、逆转录酶和蛋白酶活性分析等实验，检测分离化合物的抗HIV—1活性并探讨其作用机制一结果：红花五味子甲素能够抑制病毒诱导的合胞体形成，保护病毒感染细胞，抑制病毒在细胞内的复制对HIV-1感染细胞与正常CD4^＋细胞间的融合，逆转录酶活性有一定的抑制作用但是红花五味子甲素不抑制病毒在慢性感染细胞中的复制，也不抑制蛋白酶的活性、结论：首次从天然产物中分离得到红花五味子甲素，它对HIV—1病毒复制早期具有抑制作用

Third,focusing on the case above,hearing host,representatives of interested party ,the author carries on an argument and points out :we should select specialist host outside environment administration for hearing.Selecting system of representatives of today lacks openness,participation,effective operation,legal system, etc. we also should set such a selection as hearing administration reasonably dividing beneficial groups and interested party electing or lotting representatives.

再次，作者紧扣上述案例，从听证会主持人、利害关系人代表两方面展开了论述，结合对《环境保护行政许可听证暂行办法》的条款分析，作者指出：应当选任来自环境保护行政主管机关以外的专家主持环境行政许可听证会；现行的利害关系人代表选择机制缺乏公开性、参与性、有效操作性、法治统一性等，应当确立"听证组织机关合理划分利益群体、利害关系人推举或抽签决定出席代表"这样一种利害关系人代表选择机制。

In the part of empirical analysis of Chinese IPO first-day return, the difference between existing study and this study is that we use principal components analysis to extract from five factors to construct investors'sentiment index, add it to controled varibles, on which we examine the influence of offering mechanism on IPO first-day return. Moreover, we gather statistics and compare the IPO holding return for lockup period between fixed-price-class offering method and bookbuilding-class offering method, as well as price range between Chinese A-share market and Hongkong stock market, which prvide comprehensive evidence to appraise Chinese IPO bookbuilding mechanism. 2. Compare to the existing literatures which consider discount or allocation, incentive allocation and discount are considered at the same time in optimal mechanism design in this dissertation, and the offering bottom price is introduced to the price range. We investigate the relationship between price range and allocation quantity, and obtain the optimal price range and allocation strategy so that the advantages of independent allocation are reflected. On the other hand, the disadvantages of independent allocation are reflected in the manipulation in case of no restriction on IPO allocation. To distinguish from the existing literatures, bookbuilding mechanism is introduced to the model. We study the allocation strategy adopted by the underwriter in the pooling equilibrium of manipulation. In addition, we analyze the incentive compatibility conditions to which the existence of pooling equilibrium should satisfy and examine some factors'impact on the existence of manipulation.3. In bookbuilding without independent IPO allocation, Chinese realistic IPO background is considered and the condition of bookbuilding and fixed-price hybrid offering is added. Divide bookbuilding and fixed-price hybrid offering into sequential hybrid and simultaneous hybrid, and point out that the key points of subscription strategy in the two kinds of hybrid are different. Through modeling and simulation we obtain the impact of institutional investors'subscription strategy on bookbuilding without independent IPO allocation, which fill the gap in related research. Moreover, in the part of IPO bookbuilding with over-allotment option, the pricing strategy is divided into hot-IPO strategy and weak-IPO strategy. Take into account the procedure of Chinese IPO with over-allotment option, it presents how the underwriter determines the pricing strategy and what effect it brings to offering price and issue size through modeling and simulation. Therefore, it is instructive as a complement to existing literatures.

此外，对我国A股市场询价发行方式与固定价格发行方式下的IPO锁定期到期时持有收益率、以及我国A股市场与香港市场的询价发行价格区间进行了统计比较，为评价我国IPO市场的询价发行提供了比较全面的依据。2、相比已有文献仅考虑折价和分配中的一种激励措施，本论文在有自主配售权下的机制设计中并用了分配与折价两种激励措施，并且在价格区间的制定中引入发行底价，考察了价格区间与分配量之间的关系，得到最优的价格区间和分配策略，从中体现自主分配权的优点；在有自主分配权下的操纵行为研究中则体现了自主配售权的弊端，与已有文献不同的是，在模型中引入了累计投标询价机制，研究了承销商在混同均衡操纵中采取的分配策略，并对操纵存在的条件进行分析讨论，得出各个因素对混同均衡操纵存在的影响。3、在无自主分配权下的询价发行中，充分考虑了我国实际应用的背景，加入了与固定价格发售混合的条件，并将询价与固定价格混合发行分为序贯与同步两种方式，指出机构投资者在两种情况下申购策略的侧重点各有不同，通过对序贯混合发行方式下的网下累计投标策略以及同步混合发行方式下的资金分配策略的模型建立和数值仿真，考察了机构投资者申购策略对无自主分配权下的询价发行的影响，填补了相关研究文献的空白；在包含超额配售选择权的询价发行中，将发行定价策略分为热销策略和弱销策略，在考虑了我国含超额配售选择权的发行流程下，通过建模以及数值仿真得出承销商会对发行定价策略作出怎样的选取，进而会对新股发行价格、发售数量产生怎样的影响，对目前相关研究的缺乏做出了有益的补充。

Have brought forward some idea of perfect our country system of refunding taxes on exported goods here on the basis: Abiding by international common practice , starting with to reforming mechanism, brings export tax refund into duty on value added routine administration , makes button tax , refund of duty integration collect tax , duty-free , supports, realize the outlet goods ultimately zero tax rates, compete on international market impartially.

在此基础上，提出了完善我国出口退税制度的一些想法：遵循国际惯例，从改革机制入手，把出口退税纳入增值税常规管理，使征税、免税、抵扣税、退税一体化，最终实现出口货物零税率，在国际市场上公平竞争。〔关键词〕出口退税；国际惯例；机制，零税率；增值，退税率

This artificial order-driven stock market with relatively sophiscated trading mechanism is comprised of the two types of traders: fundamentalists and technicalist interacting with each other, differing from its predecessors that consist of the only one type of heterogeneous agents interacting in a simple trading mechanism.

另外，本文所建立的订单驱动的股票市场不仅具有比较复杂的交易机制，而且由异质的基础交易者和技术交易者两类交易者共同组成，不同于以往单一性质的交易者构成的只具有简单交易机制的金融市场。

This thesis, titled "under the Exchange rate marketization of RMB a probe into exchange rate risk management from the enterprises' standpoint ", on the basis of some basic concepts and theory about exchange rate risk , mainly discusses the significance and exigency of study exchange rate risk management in corporation of china , and raises some proposals in such aspects as removing obstacles, optimizing exchange rate risk management system and establishing the mechanism of previous tergiversation exchange rate risk. In addition, the thesis analyzes the risks that will be encountered in the development of exchange rate marketization of RMB and offers solutions to these risks.

本文选择《人民币汇率市场化下的企业汇率风险管理研究》为题，在介绍汇率风险的基本知识和相关概念、企业对汇率风险管理基本理念的基础上，结合我国实际，分析了我国涉外企业在目前人民币汇率机制改革、人民币汇率逐步市场化的前提背景下汇率风险管理的必要性和紧迫性，提出逐步完善企业汇率风险管理系统，建立企业内部风险预警机制运行模式的建议、并对人民币汇率市场化下企业所面临的汇率风险进行了分析，提出了相应的对策。

In facing of this phenomenon of dropping out of school seriously in the underdeveloped areas, there needs some useful actions to take,for example, the goverment should implement the universal implementation of the nine-year compulsory education, and constantly improve the mechanism for education and employment mechanism in order to arouse state and the whole community to pay attention to this issue.

在此基础上本文提出了针对欠发达地区辍学现象和辍学青少年情况急需展开的几项工作，如普遍落实九年义务教育，不断完善教育机制和就业机制等。以期引起国家和全社会对这一问题的重视。

This paper conducts investigation and analysis for the present maintenance mechanism of toll road in China for the purpose of finding the reform modes of it.

为探索和构建中国收费公路养护运行机制的改革模式，对现行收费公路运行机制进行了调研和分析。

Furthermore, besides considering changes in DNA methylation as mechanisms of disease, the role of epigenetics in general and DNA methylation in particular in transgenerational carcinogenesis, in memory formation and behavior establishment are brought about as mechanisms based on the cellular memory of gene expression patterns.

而且，除了考虑DNA甲基化改变作为疾病的机制外，表观遗传学一般的及DNA甲基化特别的在隔代致癌中的作用，在记忆形成和行为确立被引发作为基于基因表达模式的细胞记忆的机制。

The universal research in microscopic tribological mechanism of contact, adhesion, friction, molecular-level solid-liquid interaction, tribochemistry, triboelectricity etc, in the interaction among goetmaterials or between goematerials and artificial materials during geomotion, were reviewed and analyzed.

2综述和分析了地质运动过程中普遍存在的微观摩擦机制如接触、粘着、分子级流体-固体相互作用、摩擦化学、摩擦电性等的研究概况，认为地质摩擦学的研究应具有宏观和微观两个层次，对地质运动的微观机制的研究将促进对地质材料的地球物理、化学和力学性质的研究，并有助于对各种尺度上的地质运动过程的理解

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。