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Background Stress is a pathogenic complex of neural, endocrinal and immune response to both inner and outer stimuli that surpass the physiological threshold.

背景 应激是指内外环境刺激超过正常阈值时,机体出现的一种包括神经、内分泌和免疫系统等在内的综合应答状态。

The mice inoculated with Coxiella burnetii intrana- sally developed interstitial pneumonia,while the primary pathological changes of mice inoculated intraperitoneally are granulomas in spleen and liver.2.The pathological changes became more severe followed the dosage increasing.3.Coxiella burnetii can be detected in spleen and liver at day 2 after inoculation.the lesion became more and more serious from day 2 to day 12.The characteristic changes were observed at day 7,and recovered at day 14. 4.The reticuloendothelial system are main target of Coxiella burnetii.The pathogen was detected in cytoplasm of monocyte -macrophages of spleen, liver, lung, and endothelioid cells of blood vessel. 5. Coxiella burnetii can be found in macrophages lysosomes by electron microscopy. Most of them are round or rod, and polymorphic shape can also be observed in different size.

结果:1、通过不同感染途径的实验证实,滴鼻感染的小鼠主要表现为间质性肺炎,而腹腔注射感染小鼠则以脾脏、肝脏肉芽肿为主要病变。2、通过不同剂量的感染实验发现,随着感染Q热立克次体剂量的加大,动物病变愈加严重。3、通过感染后不同时间的动态病理学观察发现,在腹腔注射后第2d的脾和肝脏即可发现病原体,主要脏器的病理变化从第2d到第12d逐渐加重,第7d动物的病变最典型,至感染后14d动物的受损器官已开始出现修复性变化。4、 Q热立克次体主要侵害机体的网状内皮系统,在感染小鼠的肝、脾、肺和外周血管单核巨噬细胞以及血管内皮细胞胞浆中查见病原体。5、透射电镜观察可见Q热立克次体主要位于巨噬细胞吞噬溶酶体内,呈多形性,多见圆形和杆状,大小不一。

Polysaccharides in Enteromorpha with immunity effects were studied in cell culture condition.

在细胞培养条件下,观察了浒苔多糖对机体免疫的影响。

According to progress of lately Systematic Biology study and combine model Traditional Chinese Medicine theory,we can translate Traditional Chinese Medicine entrail into five function model of organism inner environment .

摘 要:在以往中医血液指纹图谱研究的基础上,根据系统生物学最近的研究进展,结合中医模型理论方法,可以把中医藏象解释为机体内环境的五个功能模块,目前在中医系统生物学研究中模块应该优先于网络分析,并从理论、网络生物学实验研究和复杂系统研究上给予证明。

All kinds of bioactive peptides were prepared from animals,plants and microbes by the means of enzymolytic effect and so on.

正是由于自由基对机体的毒害作用,使得清除氧自由基及其衍生物就变得十分必要。

Quick development of functional imageology brings the moment of researching on impairment recovery of epencephalic after stroke and the therapy mechanisms of acupuncture and moxibustion.

本研究以健康人和中风偏瘫病人为对照,在不同机体状态下进行上肢运动和针刺阳陵泉穴的脑功能影像研究,并进行激活区、纤维、病灶的三维重构和对比分析研究。1。

As an immunomodulator NO may play a role like a double-edged sword since it expresses both in immuonchalleged and immunosspresed states. 2. After received external stimulus the morphology of ependyma of SFO could be changed and varied with time course, particularly its cellular apoptosis do occur and earlier than the ordinary areas of the brain. 3. Astrocytes in SFO could express cFos protein induced by LPS, suggesting the cells may maintain homeostasis in the brain in a longer period and modulate immune state of the brain. 4. As a CVO, SFO may sense changes of blood-bearing immunosignals earlier and instantly response to them, thus as one of windows of the brain SFO do take part in immunomodulation within the brain.

通过我们的实验结果我们可以得出这样一些初步的结论:1、一氧化氮作为免疫调质参与了机体免疫,它既能在免疫激发状态下又可在免疫抑制状态下进行表达提示,NO在脑内免疫调节中的作用可能是双向的。2、穹窿下器的室管膜形态在接受外界刺激后,随着时间的变化而不同,扫描电镜下的凋亡形态虽需进一步证实,但室管膜细胞确实发生了凋亡,并且穹窿下器发生的较早。3、穹窿下器内的星形胶质细胞在给予大肠杆菌后确实可以表达c-fos蛋白,并可能通过自身的激活来较长时间的维持体液的动态平衡,调节脑内免疫状态。4、穹窿下器作为感受性室周器官之一,能够较早的感受血携免疫信息的改变并及时作出反应,可能作为外周免疫信息进入脑内的窗口之一来参与脑的免疫调节。

Current research focused mostly on the development and restoration by regeneration of cartilage of limb joints and epiphyseal growth cartilage, but it is still incipient to study the development and the mechanism of physiological rebuilding and restoration by regeneration of condylar cartilage.

机体其它组织损伤是通过瘢痕而愈合,而骨和软骨则通过自身组织的再生来完成改建和损伤的修复,此功能主要是由于胚胎时期骨架的发生与出生后骨架生理性改建及损伤修复的分子机制相似的结果。

In the present study, head-down tilt bed rest was used to simulate microgravity. We observed and compared the effects of lower limb muscular exercise with bicycle ergometric exercise during 30 days of -6°HDT bed rest on the responses of lower limb muscle and cardiovascular systems.

采用何种体育锻炼方法才能够最有效地预防和对抗航天失重环境对机体的影响,仍然是航天医学所面临的主要问题之一。

The erythrocytic response-to chronic hypoxemis is essential for the maintenance of systemic oxygen ...

机体红系造血功能因缺氧刺激而增加是一种正常的病理生理反应它对维持紫绀型先天性心脏病体内氧的供给具有重要意义。

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The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。

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