未甲基化的

Alkylation of methylnaphthalene and methanol over HZSM-5 zeolite can make 2, 6-dimethylnaphthalene (2, 6-DMN) and the product stream contains isomers of 2, 6-DMN and unreacted MN, which requires efficient separation.

以甲基萘和甲醇为原料，采用HZSM-5烷基化催化剂制取2，6-二甲基萘(2，6-DMN)。由于产物中含有2，6-DMN的异构体以及未反应的MN，需对反应产物进行有效分离。

30 Of the benign lesions is similar with the adjacent pathologicallly normal mammary tissue (104. 20±36. 56). In all of the paired benign and malignant samples, there was concordance between the expression of NES1mRNA and protein.

在所有43例患者的对照正常乳腺组织中均未发现有NES1基因CpG岛的甲基化。30例乳腺恶性肿瘤组的NES1基因的甲基化率明显高于15例乳腺良性病变组，两组差异有显著性意义（x〓=8.72，P＜0.01）。

P.05, and significantly higher in gastric cancer tissues with serosa invasion than in those without serosa invasion 35.0% vs.

5.0%(P.05)。浸润深达浆膜层的胃癌组织中甲基化阳性率与未达浆膜层组的差异有统计学意义35.0% vs。

Using pentaerythritol as initiator, boron trifluoride diethyl etherate as catalyst.dichloroethane as dispersion agent, the chloride polyether polyol is synthesized based on the mechanism of cationic ring-opening polymerization of epiclilnrohyclrin.The azide polyether polyol is synthesized, in DMF through A and sodium azide, and the non-reported azide energetic curing agent is synthesized through the adduction of B and IIDI.

以季戊四醇为起始剂，三氟化硼乙醚为催化剂，1，2—二氯乙烷为分散剂，环氧氯丙烷经阳离子开环聚合反应制成氯化聚醚多元醇，A在N，N—二甲基甲酰胺中与叠氮化钠反应制得叠氮聚醚多元醇，B与六亚甲基二异氰酸酯加成反应制得未见文献报道的叠氮固化剂。

An unreported compound 2-cyclopropylbenzimidazolium salt was obtained from 2-cyclopropyl benzimidazole and iodomethane.

以邻苯二胺和环丙基甲酸为原料，以多聚磷酸为催化剂，在微波辐射下合成了环丙基苯并咪唑，用碘甲烷季胺化得到未见文献报道的环丙基苯并咪唑盐，通过苯并咪唑盐与Grignard试剂加成后水解反应制备环丙基甲基酮。

Three part of research works had been carried out in the dissertation. The first part: a kind of multidentate amine modified silica gel was synthesized through the following steps:(1) introduce the amino groups onto the surface of silica-gel by the treatment of surface silanol groups withγ-aminopropyl trimethoxy silane;(2) michael addition of excess trihydroxymethyl propyl triacrylate to amino groups on the silica gel surface;(3) amidation of the unreacted double bonds of TMPTA on the surface of TMPTA modified silica gel with diethylenetriamine;(4) the multidentate amine modified silica gel was finally obtained by the reaction of amino groups on the surface of DETA modified silica gel with double bond of butyl acrylate.

本论文进行了三部分研究工作，第一部分：通过多步反应对硅胶进行改性合成了一种多齿胺改性硅胶配体，合成过程如下：1通过γ-氨丙基三甲氧基硅烷与硅胶表面的硅羟基反应，使硅胶表面带有氨基；2利用硅胶表面氨基与过量的三羟甲基丙烷三丙烯酸酯发生Michael加成反应；3利用二乙烯三胺与TMPTA改性硅胶表面未反应的双键发生反应使硅胶表面氨基化；4最后用丙烯酸正丁酯与DETA改性硅胶表面氨基充分反应成功合多齿胺改性硅胶配体。

In order to find highly active pesticide, three series of 5--12-substituent-benzo phenanthridine derivatives were synthesized through the reaction of 2-methylbenzonitrile with dif-ferent aldehyde, and further dehydration with DDQ or N-methylation with NaH and CH3I, respectively.

为了寻找新的高活性农药，利用2-甲基苯甲腈与不同的醛反应，再通过2，3-二氯－5，6-二氰基－1，4-苯醌脱氢或NaH和CH3I氮甲基化，合成了3个系列共18个5-取代氨基－12-取代苯并菲啶衍生物，其中15个是未见文献报道的化合物。

To economize cost of S03H-functionalized ionic liquids,extend their range of application in chemistry reaction,fifteen of ionic liquids have been synthesized by using methylimidazole,tri-alkylamine,pyridine with industrial materials 1,4-butane-sultone and 1,3-propane sultone as source in this paper.The ionic liquids were synthesized by tri-alkylamine have not been reported and yields are higher than 98%.

为了降低SO_3H-功能化离子液体的成本，使其应用范围更加广泛，本论文利用N-甲基咪唑、三烷基胺、吡啶和廉价工业级原料1，3-丙烷磺内酯、1，4-丁烷磺内酯为原料来源，合成十五种SO_3H-功能化离子液体，三甲胺为原料合成的SO_3H-功能化离子液体还未见文献报道，收率大于98%。

The protein had the same antigenicity as IgG, and the change of the protein had the same tendency as SHP-2, which was higher in canceration groups than in uncanceration groups and control groups in thymus cells, but there weren't significant change in bone marrow cells;⑧ The change law of the expression of SHP-1 and SHP-2 during γ-ray induced malignant transformation in BEAS-2B cell is that the expression of SHP-1 was increased synchronistically with malignant transformation of cell, and the expression of SHP-2 didn't have significant correlation with malignant transformation of cell.

癌变组胸腺细胞中SHP-2 mRNA编码PTPase催化区的700～1096bp间可能出现甲基化；⑦癌变组的胸腺细胞中存在一相对分子质量约为55×10〓的蛋白质，它与IgG具有相同的抗原性，其表达量的变化趋势与SHP-2的蛋白表达变化趋势基本一致，即在胸腺细胞中明显高于对照组及未癌变组，但在骨髓细胞中对照组高于癌变组；⑧SHP-1、SHP-2在γ射线诱发的BEAS-2B细胞恶性转化过程的变化规律：SHP-1蛋白表达量的升高与细胞的恶性转化在时间上基本一致，而SHP-2蛋白表达量与恶性转化无明显关系。

The unmethylated probe can be cut in the recognition site by restriction endonuclease, causing the restoration of the fluorescence of TAMRA.

限制性内切酶可切割未发生甲基化修饰的探针，导致探针的发夹结构遭到破坏，引起TAMRA荧光信号的恢复。

On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面，更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值，分为几个相等的区间作为横轴，并将各区间内所测定值依所出现的次数累积而成的面积，用柱子排起来的图形，也叫做柱状图。