未改变的

Rat glioma cell C6 was infected by the deficiency recombinant retrovirus (named C6TK). The sensitivity of C6TK cells to GCV or ACV increased 450 or 10 times than that of C6 cells respectively. Rat C6 glioma model was successfully built, and SD rats inoculated intracerebrally C6TK cells had normal gliomas. The average survival periods of the rats were about 15 days. However, after treated with ACV, the growth of C6TK tumors obviously regressed, and the survival periods extended to 57.8±8.1 days, especially in rats injected with mixed PA317TK and C6 cells or in situ PA317TK cells, which the tumors nearly disappeared after ACV administration and the survival periods extended to over 120 or 71.4±36.1 days respectively, P＜0.001.

结果：构建了带有HSV-tk基因的反转录病毒载体GINaTK，应用脂质体转移方法将GINaTK导入反转录病毒包装细胞PA317，成为产病毒细胞PA317TK，用带有HSV-tk基因的复制缺陷型反转录病毒感染C6细胞，命名为C6TK细胞，对GCV和ACV的敏感性分别高于亲本450倍和10倍；成功地建立了大鼠脑胶质瘤模型，并证实转染细胞C6TK的成瘤效应未改变，存活期约为15天；而经ACV治疗后，含有C6TK细胞的肿瘤生长明显被抑制，大鼠生存期延长为57.8±8.07天，尤其是采用PA317TK细胞混和治疗组和原位治疗组，肿瘤基本消失，大鼠生存期显著延长，混和治疗组存活120天以上，原位治疗组存活至71.4±36.1天。t检验，P值均小于0.001。

Results: GINaTK retroviral vector containing HSV-tk was constructed and transduced into PA317 retrovirus packaging cell by lipofectin (named PA317TK). Rat glioma cell C6 was infected by the deficiency recombinant retrovirus (named C6TK). The sensitivity of C6TK cells to GCV or ACV increased 450 or 10 times than that of C6 cells respectively. Rat C6 glioma model was successfully built, and SD rats inoculated intracerebrally C6TK cells had normal gliomas. The average survival periods of the rats were about 15 days. However, after treated with ACV, the growth of C6TK tumors obviously regressed, and the survival periods extended to 57.8±8.1 days, especially in rats injected with mixed PA317TK and C6 cells or in situ PA317TK cells, which the tumors nearly disappeared after ACV administration and the survival periods extended to over 120 or 71.4±36.1 days respectively, P ＜0.001.

结果：构建了带有HSV-tk基因的反转录病毒载体GINaTK，应用脂质体转移方法将GINaTK导入反转录病毒包装细胞PA317，成为产病毒细胞PA317TK，用带有HSV-tk基因的复制缺陷型反转录病毒感染C6细胞，命名为C6TK细胞，对GCV和ACV的敏感性分别高于亲本450倍和10倍；成功地建立了大鼠脑胶质瘤模型，并证实转染细胞C6TK的成瘤效应未改变，存活期约为15天；而经ACV治疗后，含有C6TK细胞的肿瘤生长明显被抑制，大鼠生存期延长为57.8±8.07天，尤其是采用PA317TK细胞混和治疗组和原位治疗组，肿瘤基本消失，大鼠生存期显著延长，混和治疗组存活120天以上，原位治疗组存活至71.4±36.1天。t检验，P值均小于0.001。

How can we, as a large-sized state-owned public hospital, adapt to the new situation where the medical system is unchanged but the business operation is changed to complete tasks assigned by HMC How can we approach the challenges when people have an over-demand for medical services but the employeesare irregular in quality How can we maintain exuberant vitality when foreign-funded hospitals flooded in after the medical market was opened, vigorous development of private hospitals at home and acute competition between public hospitals in the market economy Although there are all-around and unprecedented

作为一家大型国有公立医院，如何适应医疗体制未变，但运行机制却发生改变的形势，全面完成医管中心下达的目标任务；如何面对社会对医疗服务过高需求与员工自身素质参差不齐的考验；如何在市场经济的大潮中，面对医疗市场开放后外资医院的竞相涌入，面对国内民营医院的蓬勃发展，面对公立医院之间的激烈竞争，保持旺盛的生命力等等。

On the other hand, the polyandrous marriage system practiced by the local villagers are positive for habitat conservation, since this can reduce resource consumption (such us firewood, number of room, rangelands, farmlands) per capita in large households (that is, the number of occupants) than in small households.

这意味着在目前当地传统生产方式基本未发生改变的情况下，因人口数量增加所带来的生产等活动强度的增加是黑白仰鼻猴栖息地丧失与破碎化加剧的主要原因（R2 = 0.972）；当地人类经济活动的增加，如牧场和农田扩张，牲畜存栏数增加以及薪材采集和木质建筑等导致了栖息地丧失、退化和破碎化。

So the possibility of the powder quantity excessing the furnace's limitation pressure must be noticed . In conclusion, compared with combusting biomass in the initial condition, the method of combustion biomass in powder by the circumfluence furnace can greatly improve the combustion properties and effiency.

与传统的直接燃烧未破碎的生物质相比，粉体在回流式燃烧炉中燃烧的方式改变了破碎前生物质以固相燃烧为主的性状，极大地提高了生物质的燃烧效率和能源品位。

The fighter feinted with his right hand and struck with his left.

假动作方向上一短暂的假的或未完成的改变，用以误导对手或对方

In 1954, Sebastian Blanco of Almansa, Spain, began handcrafting Magnanni footwear from the finest leathers in the world. His original stands and vision remain unchanged.

1954年西班牙的Sebastian Blanco 开始使用世界上最好的皮革来制作Magnanni男鞋，他最初的想法和远见直至现在仍未改变。

The best available evidence suggests that climatic change since the 1970s may already be causing over 150,000 deaths annually, and that unmitigated greenhouse gas emissions would increase disease burdens in the coming decades.

已知的最好的证据提示提示20世纪70年代以来气候的改变可能已经引起了15万人死亡，而且温室气体排放量未减轻的状况将加重未来几十年内的疾病负担。

Notable among these thinkers is Parmenides, who maintained that reality is an undifferentiated oneness, or unity, and that consequently real change or individuality of things are there?

值得注意的是这些思想家巴门尼德，谁主张，实际上是一种未分化的同一性，或统一，因此真正的改变或个性的东西呢？

Notable among these thinkers is Parmenides, who maintained that reality is an undifferentiated oneness, or unity, and that consequently real change or individuality of things are there?

值得注意的是，这些思想家巴门尼德，谁坚持认为，现实情况是，一个未分化的统一性，或统一，并因此真正改变，或个性化的东西，是否有？

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。