未免疫的

The notable proliferation was not observed by eyes in the local of injection. The infiltration of inflammation cells and mild proliferation of fibrocyte around dura mater was observed by HE stained in 4 and 8 weeks after injection. Infiltration and exudation of inflammation cells was observed by HE stained in epidural nerve root. Compared with group A, no changes of group B, C and D were observed under specific stained. Proliferation of type Ⅱ collagen fibers around dura mater was seen under immunohistochemical stained in 4 and 8 weeks after injection. There is no significant demyelination changes under LFB stained. The thickness and shape of the myelin sheath in epidural nerve root was not regular under transmission electronic microscopy in 4 and 8 weeks after injection. Fibroblast was also seen there. In nerve endometrium, macrophage could be seen under TEM, myelinated nerve fiber changed significantly, but nonmyelinated nerve fiber changed mildly. When 8 weeks, the changes of group D is smaller than the group B and C.

给药局部肉眼观察未见明显的纤维组织增生；HE染色可见B、C、D三组给药后四周及八周时硬膜内外均有炎细胞浸润，纤维细胞轻度增生，硬膜外神经根内有炎细胞浸润及炎性渗出；特殊染色B、C、D三组同A组相比未见有脊髓及神经根的改变；免疫组化染色，给药后四周及八周时，硬膜内外均有Ⅱ型胶原纤维增生；固兰染色B、C、D三组未见有明显脱髓鞘改变，与A组相比无明显异常改变；电镜观察B、C、D三组在给药后的四周及八周时，表现为硬膜外神经根内髓鞘厚薄不一，形状不规则，可见成纤维细胞，神经内膜中可见有巨噬细胞；粗大的有髓神经纤维变化明显，无髓神经纤维受累较轻；八周时电镜下D组改变较B、C两组为轻。

In addition, the volume of milk in the immune substances, such as immunoglobulins, immune cells, lysozyme activity, as well as AKGs (ie alkoxy glycerol, breast milk is the milk AKGs content 10 times) and so on, did not smell and cattle colostrum to enhance your baby's resistance to a similar role in human milk.

此外，人乳中的在量免疫物质，像免疫球蛋白、免疫活性细胞溶菌酶，以及AKGs(即烷氧基甘油，母乳中的AKGs含量是牛奶的10倍)等，未闻及牛初乳对增强孩子的抵抗力有类似人奶的作用。

Based on these previous work, in this research, in order to explore the the molecular mechanism of enhanced tumor cell immunogenicity treated by elemene and mytomycin C compositely, we used murine Hca-F ascitic hepatic carcinoma ( high lymphatic metastasis substrain of H22) as an experimental model to compare the immunoprotective effects on Hca-F cells as well as the mechanism of the effects caused by HSP70-peptide complex purified from untreated tumor cells, EC-TCV and BCG; We studied the mechanism of increased tumor cell membrane HSP expression treated with elemene by the techniques of RT-PCR and immunoelectron microscopy; In order to deeply elucidate the antitumor effects and the molecular mechanism of elemene in increasing tumor cell immunogenicity we analyzed and compared the effects of elemene and heat shock on the gene expressions of tumor cell using gene expression profile chip.

本论文在上述研究成果的基础上，选择小鼠肝癌H22的高淋巴道转移亚系Hca-F为模型，进一步比较了未处理肿瘤细胞来源、榄香烯复合瘤苗来源的和卡介苗来源的HSP70-肽复合物对Hca-F的免疫保护效应、效应机制，探讨榄香烯-丝裂霉素复合处理增强肿瘤细胞免疫原性的分子机制；以Hca-F和人肝癌细胞株HepG〓等为模型研究了榄香烯处理增强肿瘤细胞膜热休克蛋白表达的机制；以HepG〓为模型用表达谱基因芯片研究比较了榄香烯与热休克处理对肿瘤细胞基因表达的影响，从而进一步阐明榄香烯抗肿瘤作用及增强肿瘤细胞免疫原性的分子机制。

Exogenic transplanted MSCs were not immune rejected,and did not initiate specific immune response during the second transplant.

MSCs异种移植未见明显的免疫排斥，不诱导机体产牛特异件免疫应答，多次移植可以改善功能恢复。

The number of CD〓 and CD〓 lymphocytes subpopulation and IgA, IgM, IgG antibody-producing cells, the ratios of CD〓 and CD〓 T-cell in the cecal tonsils and Harderian glands, the content of IgA, IgM, IgG in tear, tracheal fluid, intestinal fluid and bile of CIAV-infected chicks vaccinated with ND vaccine were significantly decreased compared with vaccinated control chicks 7～28 days PV.

CIAV感染雏鸡ND免疫后28天内，哈德尔腺、盲肠扁桃体以及泪液、气管液、肠液、胆汁的上述各项免疫学指标，均不同程度的明显低于未感染CIAV的ND免疫雏鸡，表明CIAV感染雏鸡呼吸道和消化道局部粘膜对ND疫苗的细胞和体液免疫应答机能下降。

D immunoglobulin is administered to Rh-negative,unsensitized patients to prevent isoimmunization.

为避免同种免疫，给未致敏的Rh血型阴性患者注射D免疫球蛋白。

Observe the influence of combination therapy with microwave ablationand peritumoral injection of immature dendritic cells on survival and tumor growth in mice.Observe clinical safety of combination therapy with MWA and adoptive immunotherapy of dendritic cells and eJector cells.Research the change of percentage of lymphocyte subsets and concentration of cytokine in peripheral blood after combination therapy.Initially observe the short-term result of combination therapy.

目的摸索微波消融治疗时有效灭活肿瘤细胞并释放肿瘤抗原的温控和能量条件；观察肝癌消融后局部注射未成熟树突状细胞对荷瘤小鼠生存期及肿瘤生长的影响；观察肝癌微波消融联合树突状细胞疫苗及效应细胞综合过继免疫治疗的临床安全性，研究微波联合细胞免疫治疗后近期外周血淋巴亚群比例及细胞因子浓度的变化，初步探讨细胞免疫治疗对肝癌微波消融后近期复发率的影响。

GnRH-ir fibers distribute in the various brain region from the olfactory bulb to the cerebellum. They are especially abundant in the hypothalamus, the preoptic area and the ventral telecephalon. The immunopositive reaction in precocious fish is evidently stronger than that in unprecocious fish, and there is only very weak reaction in the gonadal undeveloped fish. The differences are most obvious in the hypothalamus, but not in other areas.

性早熟大黄鱼的神经内分泌细胞对GnRH抗血清的免疫阳性反应明显，无论在细胞的数量和免疫强度都比未早熟鱼多和强，在性腺尚未发育的幼鱼脑中仅有弱的免疫阳性，这种差异在下丘脑外侧结节核及视前核处最为明显，在其它GnRH阳性部位则差异不显著。

Indirect immunofluorescence was used to observe the distribution of fibronectin in human oocyte and 2-cell to morulae embryos.

纤维粘连蛋白均匀分布在体外未受精人卵母细胞和受精后人胚胎早期发育的不同阶段的卵裂球表面，各时期的免疫荧光强度未见明显差别。透明带未见纤维粘连蛋白表达。

According to correlative literatures, the diagnosis and treatment of bronchiolitis obliterans syndrome in three patients with hematological malignancies after allo-HSCT were analyzed. The function of haematopoiesis re-established successfully. The acute graft versus host disease did not occur in these patients except one patient occurred grade Ⅱ aGVHD, and the chronic graft versus host disease occurred in the 5th, 6th and 6th months after allo-HSCT respectively, but the cGVHD was recrudescent after treatment. The bronchiolitis obliterans syndrome occurred in the 9th, 7th and 11th months after allo-HSCT respectively, and they received the treatment of immunosuppressive, immune human serum globulin, azithromycin and to breathe in β2 receptor agonist and budesonide.

结合相关文献，对3例恶性血液病患者异基因造血干细胞移植后发生闭塞性细支气管炎综合征的临床特点和诊断治疗进行分析。3例患者移植后造血功能均顺利重建，2例未发生急性移植物抗宿主病，1例发生II度急性移植物抗宿主病；3例患者分别于移植后5，6，6个月发生广泛型慢性移植物抗宿主病，经治疗后病情仍有反复；3例患者分别于移植后9，7，11个月发生闭塞性细支气管炎综合征，给予免疫抑制剂、静脉免疫球蛋白、阿奇霉素及局部使用β2受体激动剂及布地奈德吸入治疗，2例在治疗4周后病情有所改善，另1例病情无改善。

However, as the name（read－only memory）implies, CD disks cannot be written onorchanged in any way.

然而，正如其名字所指出的那样，CD盘不能写，也不能用任何方式改变其内容。

Galvanizes steel pallet is mainly export which suits standard packing of European Union, the North America. galvanizes steel pallet is suitable to heavy rack. Pallet surface can design plate type, corrugated and the gap form, satisfies the different requirements.

镀锌钢托盘多用于出口，替代木托盘，免薰蒸，符合欧盟、北美各国对出口货物包装材料的法令要求；喷涂钢托盘适用于重载上货架之用，托盘表面根据需要制作成平板状、波纹状及间隔形式，满足不同的使用要求。