期

The author concludes that the last deglaciation climate variation in the proxy records for the east Asian monsoon has an asymmetric shape; the warming events are abrupt and the cooling events are gradual.

指出东亚季风区末次冰消期气候的不对称性即从暖期向冷期的渐变以及从冷期向暖期的突变过程。

Prophase may be divided into successive stages termed leptotene, zygotene, pachytene, diplotene, and diakinesis.

前期可被分为连续的阶段：细线期、偶线期、粗线期、双线期和终变期。

Methods: Cells which belonged to the G1-phase were sorted by Multiparameter flow cytometry according DNA diploidy in asynchronous MOLT-4 cell lines, cells were synchronized at the G1-S boundary by thymidine, and western blot analysis and multiparameter analysis of DNA versus protein content was performed to examine cyclin A、B1、D〓、Eexpression in sorted G1-phase MOLT-4 cells and synchronized by double thymidine block in G1/S phase.

以MOLT-4细胞为模型，应用流式细胞术分选出非同步化生长的G1/S转换期起始处的G1期细胞，用"双thymidine阻滞法"将细胞同步在G1/S转换期起始处的G1期，采用DNA/cyclins双参数分析法及免疫印记法，检测同步化及非同步化G1期细胞中cyclinA、B1、D〓、E的表达。

Firstly, place an expander under the normal skin of the cervical part and effuse. then form skin tube using the expanded flap. thirdly, the skin tube is transposed to the postauricle area.

手术分4期进行：ⅰ期在颈下部正常皮肤处埋置扩张器，注水扩张；ⅱ期取出扩张器，利用扩张皮瓣形成皮管；ⅲ期皮管转移至耳后；ⅳ期以皮管为供皮区，行外耳再造术。

MethodsFour stages are required in the whole process of ear reconstruction. Firstly, place an expander under the normal skin of the cervical part and effuse. Then form skin tube using the expanded flap. Thirdly, the skin tube is transposed to the postauricle area. At last, conduct ear reconstruction utilizing the skin tube.

手术分4期进行：Ⅰ期在颈下部正常皮肤处埋置扩张器，注水扩张；Ⅱ期取出扩张器，利用扩张皮瓣形成皮管；Ⅲ期皮管转移至耳后；Ⅳ期以皮管为供皮区，行外耳再造术。

Based on the brand life cycle theory and the complexity of the market,this article proposes that a medicine brand life cycle consists of five phases,i.e.,the precursor,appearance,cognizance,famousness and decline.It also analyses the feature of each phase and the relevant marketing strategy f...

文章从品牌生命周期理论出发，结合药品市场的复杂性，提出了药品品牌生命周期，将其分为前导期、产生期、知晓期、知名期、衰退期五个阶段，分析了各个阶段特点，并针对每个阶段提出了相应的药品营销策略。

Further we divided the stand phase into three phases including loading response phase, mid stand phase and push off phase. In the loading response phase flat foot group presented higher frontal plane and saggital plane motion at rearfoot. In the mid stand phase they had higher midfoot motion at frontal plane.

将站立期细分成承重反应期、站立中期、推进期，则发现在承重反应期后足冠状面及矢状面活动角度大於正常足，站立中期中足冠状面活动角度大於正常足，推进期后足矢状面活动角度少於正常足。

The frequency of spontaneous UP/DOWN transitions could be entrained to a regular interval by repetitive sound stimuli with intervals ranging 3-12 sec, in which each sound stimulus effectively induced a UP-to-DOWN transition.

外界声音刺激（白噪声，0.1-35 KHz）能调制神经元自发的高电、低电位期的传递节律：当声音刺激落在高电位期时，每一次声音刺激都会使细胞膜电位由高电位期向低电位期转变，并当声音刺激间隔在3-12秒范围内时，自发的高、低电位期的转变节律就同步于声音刺激的重复率，即跟随效应。

Prehypertensive subjects versus normotensive subjects had significantly higher body mass index and subscapular skinfold, systolic and diastolic blood pressures, and triglycerides beginning in childhood; higher glucose in adolescence; and higher low-density lipoprotein cholesterol, fasting insulin, and insulin resistance index in adulthood. Hypertensive subjects versus normotensive subjects had higher adiposity measures, SBP and DBP, glucose, and triglycerides beginning in childhood; higher insulin and insulin resistant index in childhood and adulthood; and lower high-density lipoprotein, cholesterol in adulthood.

与正常血压者相比，高血压前期者其幼年期基础体重指数、肩胛下皮肤皱褶厚度、收缩压和舒张压、甘油三脂等指标更高；在青春期血糖水平更高；在成年期低密度脂蛋白胆固醇、空腹胰岛素、胰岛素抵抗指数更高；与正常血压者相比，高血压者在幼年时基础水平的肥胖积分、SBP 和DBP、血糖、甘油三脂等更高；在幼年期和成年期胰岛素和胰岛素抵抗指数水平均更高；在成年期高密度脂蛋白胆固醇水平更低。

In this paper, we studied M. meretrix ferritin, cathepsin B and caspase genes, which are involved in clam larval shell formation, nutrition, metabolism and apoptosis, respectively. We have cloned the three genes, investigated the temporal and spatial expression profile both at gene and protein level in trochophore (L1), D-veliger (L2), pediveliger (L3) and postlarvae (L4). The potential roles of these proteins were analyzed with specific inhibitors during larval development. Firstly, embryos were found developed into trochophore-like larvae with no shell if cultured at gastrula stage in artificial seawater without iron. Shell-like structures were formed only in the presence of iron. The larvae which had been transferred at L1 stage into ASW developed normal shell. This indicated that iron and iron associated protein are important for larval shell formation. The EST sequence which is homologous with ferritin, which is a principal iron metabolic protein, was selected from the M. meretrix cDNA library. The full-length of ferritin subunit cDNA was cloned by RACE. The results of real-time PCR revealed that the MmeFer mRNA expression changed before and after the larval shell formation.

本论文以文蛤幼虫为研究对象，分别对文蛤幼虫发育过程中贝壳形成相关的铁蛋白、营养及变态相关的组织蛋白酶B及变态过程中细胞凋亡相关的caspase三个基因进行了克隆，分析了基因及编码蛋白在担轮幼虫期(L1)、D形幼虫期(L2)、壳顶幼虫期(L3)和稚贝期(L4)的时空表达特征，解析了其可能的功能，并研究了相应酶类的特异性抑制剂作用对幼虫发育过程的影响，进行了目标蛋白的功能验证，详述如下：研究结果显示，在文蛤胚胎发育到原肠胚时放入不含铁离子的人工海水中培养，发育成无壳的畸形，随着人工海水中铁离子添加浓度的升高，幼虫长出壳状组织接近正常状态；而发育到L1期幼虫放入不含铁离子的人工海水中培养却可以发育出正常的壳，推测铁和铁代谢相关蛋白在幼虫贝壳初始形成有重要的作用。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐