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An infectious viral disease occurring in dogs, characterized by loss of appetite, a catarrhal discharge from the eyes and nose, vomiting, fever, lethargy, partial paralysis caused by destruction of myelinated nerve tissue, and sometimes death.

犬热病发生在狗身上的一种传染性病毒引起的疾病,主要特征是:无食物欲,眼鼻处有黏液,呕吐,发烧,昏睡,由于有髓鞘的神经组织受到损害而部分麻痹,有时会导致死亡

Results MRI findings of central neurocytoma are specific in 5 cases. The ganglioglioma was found in the tempora and occipital lobe in 7 cases,in the brainstem in 1 case, cystic-solid tumor was observed in 5 cases with extramural nodule in 3 cases, obviously thickened gyri were revealed in 1 cases and central necrosis in 2 cases.The 3 cases of Lhermitte-Duclos disease include the specific molecular layer imaging features.

结果 5例中枢神经细胞瘤有一定的MRI特征,3例诊断正确。8例神经节细胞胶质瘤中,7例位于或主要位于颞、枕叶,1例位于桥脑和延髓,表现为囊实性者5例,实性部分位于囊外的有3例,呈实性表现为局部脑回增厚者1例,囊变坏死明显者2例。3例小脑发育不良性节细胞瘤有特征性的条纹状或分层状表现。

RESULT: 1.Ouabain act on lens sodium-pump,under the LM,lens anterior capsular membrane discontinuous,epithelium cells clustered,occluding zonule seperated,lens fiber layers fractured.Under the EM,cells totally hollowed,mitochondria swelling,myelin figure appeared.RT-PCR examine the expression condition of αsubunit of sodium pump on mRNA level,α1、α2 and α3-isoform are all decreased.2.Digoxin act on lens sodium-pump,under the LM,lens cell oedema,linkage distructed,extensive exfoliation.Under the EM,plasma appeared little half-transparant hollow region,mitochondria swelling and ridge disappeared. RT-PCR examine,α1、α2 and α3-isoform are all decreased.3.Amphotericin B act on lens sodium-pump,under the LM,lens epithelium cells linked tightly,arranged in-line,lens fiber layers arranged tightly and regularily.Under the EM,abbundant cellular organes,exuberant cells function indicated. RT-PCR examine the expression condition of αsubunit of sodium pump on mRNA level,α1 and α3-isoform are increased significantly,demonstrated isoform-specific action.4D-thyroxine act on lens sodium-pump,under the LM,lens plasmalemma integrated,cells arranged tightly and regularily.Under the EM,nucleus fission appeared,desmosome half-desmosome and tensile microfilaments linked the cells. RT-PCR examine,α2 and α3-isoform are increased, also demonstrated isoform-specific action.5.Vitamin E act on lens sodium-pump,under the LM,lens anterior capsular membrane continuous and smooth,epithelium cells tightly linked,lens fiber layers appearede hollow region occasionally.Under the EM,lateral membrane high density belt appeared,abundant nucleolus. RT-PCR examine,onlyα1-isoform are increased, demonstrated significantly isoform-specific action.6.DMSO act on lens sodium-pump,under the LM,lens anterior capsular membrane slightly thicker,cells linkage partly distructed.Under the EM,plasmalemma denaturation,mitochondria swelling.RT-PCR examine,α1、α2 and α3-isoform are all altered slightly and haven't significant meanning.

结果:1、哇巴因作用于晶状体钠泵后,光镜下晶状体前囊膜断裂、上皮细胞聚积、闭合连接分离、纤维板层裂隙,电镜下全层细胞空泡化、线粒体肿胀出现髓样结构,RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达均减弱。2、地高辛作用于晶状体钠泵后,光镜下晶状体细胞水肿、细胞连接破坏、广泛剥离,电镜下胞质见少许半透明空化区、线粒体肿胀嵴消失,RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达均减弱。3、两性霉素B作用于晶状体钠泵后,光镜下晶状体上皮细胞紧密连接、线状排列、纤维板层紧密规整,电镜下细胞器丰富、细胞功能旺盛,RT-PCR法检测α1及α3表达显著增强、具有一定的重整异构作用特异性。4、D甲状腺素作用于晶状体钠泵后,光镜下晶状体质膜完整、细胞排列紧密规整,电镜下胞核见分裂像、细胞间有桥粒、半桥粒及张力微丝,RT-PCR法检测α2及α3表达均增强、亦有一定的重整异构作用特异性。5、维生素E作用于晶状体钠泵后,光镜下晶状体前囊膜连续光滑、上皮细胞紧密连接、纤维板层偶见空化,电镜下囊侧膜内有高电子密度带、细胞核仁丰富,RT-PCR法检测仅有α1的表达显著增强、具有极强的重整异构作用特异性。6、二甲基亚砜作用于晶状体钠泵后,光镜下晶状体前囊膜轻度增厚、细胞连接部分破坏,电镜下质膜变性、线粒体肿胀,RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达无显著改变。

Methylene blue-basic magenta staining and electron microscopy Regenerating nerve were arranged in bundles in group A and B, there were minifascicle formation and a large amount of proliferated collagen in between the minifascicled, no cicatrices form, regenerating vasa spread randomly, electron microscopy show a large number of myelinated and unmyelinated fiber arranged in buddies.

亚甲基蓝-碱性品红染色及电镜观察两组均见再生神经纤维呈束状分布,有多个神经束,每一个神经束内见大量密集、粗大的有髓神经纤维,神经束之间充满增生的胶原,未见瘫痕形成,再生血管散在分布。

Although each of the sensory and motor regions is myelinated and functions independently before a person is five years of age, the principal regions of the brain that underlie our ability to integrate visual, verbal and auditory information rapidly are not fully myelinated in most humans until five years of age and after.

虽然每一种感觉和运动的地区是有髓和职能的独立之前,一个人是5岁以下,主要地区的大脑理解我们的整合能力视觉,语言和听觉信息迅速没有得到充分的髓在大多数人,直至5岁以下和后。

In the end, we simulate the influence of eachmembrane parameter to the propagation velocity for myelinated fibers andunmyelinated fibers, respectively, which can enhance the usability of the twocomputational models.

最后,分别仿真了有髓及无髓神经纤维细胞膜各参数的变化对兴奋传递速度的影响,增强了两个计算模型的可应用性。

Myelinated fibers in big idameter AchE has significant difference among contents in 3 kinds of end branches of internal nerve muscular branch.

在腓肠肌内侧头神经肌支的三终支内,乙酰胆碱脂酶反应阴性的大直径有髓神经纤维含量均有显著性差异。

Nevertheless there have general positive expression of Wnt5a in cases of nonmalignant hematologic diseases.

在31例血液病标本及髓系白血病细胞株中,除ALL外,有明显的Wnt5a表达缺失或降低,而非恶性血液病例中Wnt5a表达普遍呈阳性,提示Wnt5a的表达下调可能与髓系白血病的发生有关。

The adipose derived stem cells of inbreds train of rat wereinduced to differentiate into schwann-like cells and the cells were injectedinto the acellular nerve allograff.The proliferation or adhersion of these cells on the graft were observed by inverted microscope or ScanningElectronic Microscope. Activity of cells were detected using MTT. 10mmnerve gap of inbreds train of rats in two group were bridged by tissue-engineered peripheral nerve or autogenous nerve, the effect wereappraised by naked eye, recovery rate of sciatic function index,nerve-electrophysiological, histology, Transmission ElectronMicroscopy and quantitative analysis of recovery rate of myelinated fiberpopulations,diameter of myelinated fiber and thickness of myelin sheat.

按照前述方法培养并诱导近交系大鼠脂肪干细胞向类Sehwann分化,将诱导分化的脂肪干细胞悬液注入已制备的去细胞同种异体神经支架管中,倒置显微镜观察细胞生长情况;扫描电镜下观察细胞在材料上附着情况;四唑盐比色试验测定细胞活性;取两组近交系大鼠,分别用组织工程化神经和自体神经桥接10mm神经缺损,通过大体观察、坐骨神经功能指数恢复率的测定、神经电生理的测定、组织学光镜观察、透射电镜观察、再生有髓神经纤维计数恢复率、神经纤维直径恢复率、髓鞘厚度恢复率的测定等指标评价实验效果。

Fig 1 At the experimental side, two weeks after operation (HE ×100) Many pieces of cartilage cells and spindle-shaped mesenchymal cells were found, by light microscope Fig 2 At the experimental side, twelve weeks after operation (HE ×100) Medullary cavity had formed, which contained hemoblasts and adipocytes, but the trabculae was not typical, by light microscope Fig 3 At the experimental side, twenty-four weeks after operation (HE ×100) The typical cancellous bone had formed, by light microscope Fig 4 At the control side, twenty-four weeks after operation (HE ×100) A large part of CXB was degraded, resorbed and replaced by fibrous tissue, but there was'not any new formed bone, by light mocroscope

图1 实验侧术后2周(HE ×100)镜下可见很多软骨细胞条索和团块生成及大量梭形间充质细胞图2 实验侧术后12周(HE ×100)镜下可见有髓腔形成,内含有造血和脂肪细胞,骨小梁尚不典型图3 实验侧术后24周(HE ×100)镜下可见形成典型的松质骨结构图4 对照侧术后24周(HE ×100)镜下可见大部分CXB被降解吸收,为纤维组织替代,无新骨形成

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On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面,更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值,分为几个相等的区间作为横轴,并将各区间内所测定值依所出现的次数累积而成的面积,用柱子排起来的图形,也叫做柱状图。

You rap, you know we are not so good at rapping, huh?

你唱吧,你也知道我们并不那么擅长说唱,对吧?