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At 8 weeks postoperatively, the grafts were mostly substituted by new cells, and the artificial ligament was completely parceled by the synovial membrane, but there were still some gaps; The combined tendon exhibited no loose or disfiguration, the infiltrative inflammatory cells disappeared. The cells in grafts were close to normal cells in anterior cruciate ligament, but fibrocytes arranged in disorder and fibers showed a verticality.

移植后第8周,移植物大部分组织被新长入的细胞替代,人工韧带被滑膜完全包裹,浸润的炎症细胞基本消失,部分接触面已融合,但部分面仍有间隙;联合肌腱无变形和松弛,移植物内细胞形态,数量接近正常前交叉韧带,但纤维细胞排列杂乱,纤维有了一定的纵向性。

Results: The PCNA mean labelling index was 48.84%± 13.63%, and the apoptotic labelling index was12.26‰± 5.20‰. The Kaplan-Meier survival curves showed that the postoperative survival time of the patient was shorter when the tumor infiltrated to the adventitia of esophagus,with lymph node metastasis, without keratinization, PI ≥ 40% or AI<10‰. Using forward multivariate Cox regression analysis, only the parameters of pN category and PI could be verified as independent prognostic factors.

结果:36例手术切除的食管鳞癌组织平均PCNA表达指数(PCNAlabellingindex,PI)为48.84%±13.63%,细胞凋亡指数(apoptosisindex,AI)为12.26‰±5.20‰;PI升高与患者年龄小、分化程度低、有淋巴结转移和肿瘤进行性浸润呈正相关,而AI升高与分化程度高、角化明显呈正相关;绘制Kaplan-Meier生存曲线,发现病变侵及食管外膜、有淋巴结转移、无角化、PI≥40%或AI<10‰的患者术后生存率明显降低;COX比例风险模型分析,发现只有淋巴结转移和PI是影响预后的独立因素。

Results:(1)Among 40 rats, 36 rats were successfully established and the rate of success is 90 percent;(2)All the successfully established models demonstrated polydipsia, polyuria and the body weight was not increased. 6 rats suffered cataract after 3 months, and 4 rats died in 6 months;(3)There was an approximately 61% loss of retinal ganglion cells in the central retina and the thickness of retina thinner under microscope ( P 0.01 ).(4) Electroscope changes include the thinner of retina, disorganization of the membranous disc of the rod cells and the thickness of basal membrane of vessal.(5)In normal group, 1 month dibetes mellitus and 1 month treatmen group, there was no expression of ERK1/ERK2 on the retina tissues. In 3 month diabetes mellitus group, the expression of ERK1/ERK2 was positive.

结果:①40只建模大鼠中36只建模成功,建模成功率为90%;②建模成功的大鼠都表现出多饮、多尿、消瘦、体重不增的表现,有6只大鼠在3个月后出现白内障,有4只大鼠在喂养接近至6个月时死亡;③HE染色光镜下6个月大鼠后极部视网膜节细胞层细胞数明显减少,减少约61%(P.01),后极部视网膜明显变薄(P.01);④电镜观察,视网膜变薄,视杆细胞膜盘紊乱,血管基底膜增厚等表现;⑤正常组、糖尿病组和治疗组1个月大鼠视网膜中未见ERK1/ERK2的表达,糖尿病组视网膜组织中3个月时可见少量表达,ERK1/ERK2表达部位为神经节细胞层和内核层;6个月时表达强阳性,部位表达不仅见于内核层、神经节细胞层,色素上皮层也见表达。

The females incubated at 33 , their ovarium has powerful cortex, the germinal epithlium produce oocyte, its medulla degenerate into ovarian cavity. During sexual differentiation, mitochondria and smooth endoplasmic reticulum in cells of ovary increase in quantity, they disintegrate after sexual differentiation. There are a lot of big grana in cells of ovary before sexual differentiation, in the course of sexual differentiation the quantity of the big grana decrease, while small grana increase and peakafter sexual differentiation. The males incubation at 26 , cortices of their testes degenerate into a thin albuginea. Medulla are formed by testicular cords in which scatter spermatogonium.

33℃下孵化的小龟卵巢皮质发达,由原始生殖细胞产生卵原细胞,髓质退化成为卵巢腔,分化时卵巢细胞的超微结构显示线粒体和内质网的数量大大增加,它们在分化结束后解体,分化前细胞内有较多的大颗粒,在分化中大颗粒减少,小颗粒增多,在分化后小颗粒达到最多。26℃下孵化的小龟精巢皮质退化成为一层薄的白膜,髓质有许多睾丸管构成,管腔内有散落排列的精原细胞。

IAs to the uniformity of MAO Coatings and efficiency of MAO Process, assumption aboat breakdown was brought up. From microcosmic viewpoint, the Al_2O_3/Al interface was accidented. Because of skin effect, protuberant region is electric-charge-rich (electron-pool) region and concave region electric-charge-pool (electron-rich) region at the anode-positive-loaded half cycle.

对微弧氧化的击穿放电机制,提出了一种基于趋肤效应的假设:氧化膜和铝基体的界面凹凸不平,在微观上有许多尖端和凹区,由于电荷在铝表面有趋肤效应,尖端形成富电荷区而微观凹区形成贫电荷区。

The leaf epidermis structures of 6 species of Rhododendron had been observed under LM and SEM. The results show that all share together common features as follows: the leaf blades are typical back-abdomen bifacial types, the upper epidermis are formed by two or three layer bigger cells which inside layer cell is bigger than outside one, and the upper epidermis are covered with thicker cuticle.

利用光学显微镜和扫描电子显微镜观察了6种杜鹃属植物的叶片结构,结果表明,它们具有共同形态结构特征:典型的异面叶,上表皮由2~3层细胞组成,内大外小或内、外等大,有较厚的角质膜,无气孔器分布;下表皮均由1层细胞组成,排列紧密;栅栏组织由2层以上长柱形细胞组成,排列紧密;海绵组织细胞较短,排列较疏松,细胞间隙较大;均有表皮附属物。

Objective To study the relationship of endangium proliferation and the expression of metalloproteinases and tissue inhibitors of metalloproteinases after angioplasty of iliac artery in rabbits to investigate the probable mechanism of composite Danshen pill in prevention and treatment of restenosisMethods 30 white male rabbits of Japan (the average body weight was 25~30 kg)were randomly divided into 3 groups:normal control group,model group (intima destroyed by balloon and given hypercholesterol diet),CDP group (intima destroyed by balloon and given hypercholesterol diet plus drug CDP 150 mg/d),10 ones each groupResults The results of iliac artery angiogram and the analysis of pathology:there were lumens stenosis,thinner intima,smaller intima area,in CDP group compared with those in model group,and ratio of intima and tunica media thickness and area among each group (P<001)Immunohistochemistry analysis:the MMP2,MMP9,TIMP1,TIMP2 in model group significantly increased than those in control group (P<001)The CDP group had lower MMP2 and MMP9 expression,higher TIMP1 and TIMP2 expression,and increased MMP2/TIMP1,MMP9/TIMP2 than model group (P<001)The thickening of vascular neointima and stenosis degree of vascular lumen were relevant to MMP2 and MMP9 (r=0896,P<001)Conclusions MMP and TIMP play the very important role in the restenosis process of arteryCDP could inhibit the thickness of vascular neointima after balloon injury,the probable mechanism of which may be inhibiting collagen formation,smooth muscle immigration and decreasing hyperplasia of intima by interfering expression of MMPs and TIMPs

目的 研究兔髂动脉成形术后血管内膜增生和基质金属蛋白酶及其抑制物表达之间的关系,探讨复方丹参滴丸预防再狭窄的可能机制。方法健康成年二级雄性日本大耳白兔30只,平均体重25~30 kg。随机分为3组:正常对照组10只,模型组10只(球囊内膜剥脱加高胆固醇饮食),治疗组10只(球囊内膜剥脱加高胆固醇饮食以及复方丹参滴丸150 mg/d)。结果兔髂动脉造影、血管病理图像分析检测结果:①复方丹参滴丸组较模型组血管造影示管腔直径狭窄、内膜厚度减少、内膜面积减少、内膜厚度和中膜厚度比、面积比,各组之间有显著性差异(P<001)。②免疫组化分析:模型组MMP2、MMP9、TIMP1、TIMP2表达均高于对照组(P<001);复方丹参滴丸组MMP2、MMP9的表达低于模型组,而TIMP1、TIMP2的表达高于模型组;TIMP1/MMP2、TIMP2/MMP9明显增加,差异有显著性(P<001)。③内膜的增生以及管腔的狭窄程度与MMP2、MMP9有很好的相关性(r=0896,P<001)。结论 MMP和TIMP在再狭窄形成中起重要作用;复方丹参滴丸能够明显抑制血管损伤后的内膜增生,可能的机制是通过影响金属蛋白酶MMP2、MMP9及其抑制物TIMP1、TIMP2的表达从而抑制胶原的生成、平滑肌的迁移、增生,而减少内膜的增生。

The results showed that bulb height and flower size of 'Large Copper' were least, with longest white short soft hair on stem. Obvious characteristics of 'Toronto' were nacarat and lackluster membranous bulb scales, leaves with rufous stripe and base of perianth shape and colour. Obvious characteristic of 'Pink Impression' were taller plantlet, bigger flower, taller and wider leaves and edge of leaves with short hair.

结果表明:品种Large Copper的种球高度和花径均最小,茎上白色柔毛最长;品种Toronto的显著特征是种球的膜质鳞片为桔红色,无光泽,叶片上有红褐色条纹,花被片基部为黑色舌形;品种Pink Impression植株高,花大,叶片长而宽,叶缘有短毛。

Any of various swimming and diving birds of the family Podicipedidae, having a pointed bill and lobed, fleshy membranes along each toe.

科中能游泳并潜水的任一种鸟类,有尖尖的喙,脚趾间有蹼状的肉膜

Western blot was used to examine the phosphorylation of NR2A in rat hippocampus. Results Both Src and Fyn antisense ODNs could decrease the phosphorylation of NR2A induced by cerebral ischemia/reperfusion, while administration of Src antisense ODNs had more suppressive effect on the phosphorylation of NR2A than Fyn antisense ODNs.

对NR2亚基有磷酸化调节作用的是Src家族酪氨酸蛋白激酶(Src family of protein tyrosine kinase, Src PTKs),这是一类膜结合的非受体酪氨酸蛋白激酶;现已知Src家族成员中Src、Fyn、Yes、Lyn、Lck在中枢神经系统中均有表达。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

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双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。