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The results show that all the hmgr genes from pigs, cattle and chickens are astable enzyme proteins with the same gene sequence characteristics and encoding protein and physical and chemical properties; all the amino acid sequences have a high degree of homology, containing two conservative HMG-CoA binding motifs and two NADPH binding motifs; all the amino acid sequences, containing signal peptide, are secreted proteins; they are all hydrophobic transmembrane proteins with five transmembrane domains; random coil and α-helix are the main structural elements in the HMGR polypeptide chain; all the predictions of three-dimensional structure are V- shaped; there are more closer evolution relationship between the HMGR gene from pigs and cattle.

结果表明:猪、牛和鸡HMGR基因序列特点及编码蛋白质理化性质基本相同,均属不稳定类酶蛋白;保守结构域氨基酸序列具有高度的同源性,均含有保守的2个β-羟基-β-甲基戊二酸单酰辅酶A结合基序和2个还原性烟酰胺腺嘌呤二核苷酸结合基序;均有信号肽,属分泌型蛋白质;属于跨膜的疏水性蛋白,均有5个跨膜结构域;无规则卷曲和α-螺旋是HMGR多肽链中的主要结构元件;三维结构预测都呈"V"字形;猪和牛HMGR基因的进化关系最近。

Stamens 5, usually inserted at base of corolla tube and adhering to stigma head to form gynostegium; filaments usually connate to form a tube enclosing ovaries; anthers 4-celled (Periplocoideae and Secamonoideae) or 2-celled, often with a membranous apical appendage; pollen tetrads contained loosely on a spatulate translator with a basal corpusculum, or pollen united into waxy pollinia, each attached through a caudicle to the retinaculum between adjacent anthers to form a pollinarium, pollinia 2 or 4 per pollinarium.

雄蕊5,着生于花冠筒的基部,与柱头贴生,和柱头粘生,形成合蕊柱;花丝通常合生成管包围子房;花药4室(Periplocoideae和Secamonoideae)或者2室的,通常有一膜质的顶端附属物;四合花粉松散地着生于匙形的载粉器上,具有着粉腺体,或者花粉合生成腊质的花粉块,通过花粉块柄与系接于着粉腺上,每个花药有花粉块2个或4个。

Alanine, glycine and glutamine, and present weak resonances of creatinine also; diabetes mellitus patients show hyperglycorrhachia and strong resonances for ketone bodies and glycine; patients with benign prostatic hypertrophy or urethral stone have high levels of creatinine; the genital tumor females can be distinguished with low pyruvate levels on the bases of /sup 1/H-NMR spectra.

以下乃是由上述样品族群之氢光谱所得之结论;孕妇的脑脊髓液具有低浓度的脊髓糖;胺基酸(如丙氨酸;麸氨酸和甘氨酸)和肌酸酐;有酮体生成,糖尿病患的脊髓液在氢核光谱显示高浓度的脊髓糖,另外有丙酮酸;乙醯乙酸盐和甘氨酸的强烈共振讯号,而具摄护腺肥大症或是尿道结石的病患,具有高浓度的肌酸酐在其CSF的氢光谱中。

The suspicion of cancer is increased by the following factors:(1) age (young patients are more susceptible);(2) sex, if the patient is a man (more women have thyroid cancer by a ratio of 2:1, but women have more thyroid disease by a ratio of about 8:1; thus, a man with a nodule should be regarded with greater suspicion);(3) a solitary nodule (multinodular lesions are usually benign unless there is a dominant cold nodule by thyroid scan);(4) a cold nodule on thyroid isotopic scanning (hot nodules are seldom cancerous);(5) a history of radiation exposure to the head, neck, or chest, especially in infancy and childhood (eg, for an enlarged thymus or enlarged tonsils, acne, or lymphoma);(6) radiographic evidence of fine, stippled psammomatous calcification or dense, homogeneous calcification;(7) recent or rapid enlargement; and (8) stony-hard consistency.

下列因素可增加癌的可疑性:(1)年龄;(2)性别,如果病人为男性(女性与男性的甲状腺癌比为2:1,但女性更多的是得甲状腺病,约为8:1,因此,男性有甲状腺结节时应考虑癌的可能性更大);(3)孤立小结(多结节病变一般为良性,除非甲状腺扫描时呈明显的冷结节);(4)甲状腺同位素扫描时发现冷结节;(5)有过头、颈、胸放射接触史,尤其是婴儿和儿童期(例如,因胸腺增大或扁桃体肿大、痤疮或淋巴瘤等);(6)X线片见细、斑点状、沙粒样钙化或致密、匀质钙化;(7)最近增大或快速增大;(8)质地石头样坚硬。

Likewise, most people infected by the suspect adenovirus do not appear to become seriously ill.

大多数有感冒或流感症状的人不会有什么危险,邮报的报道称,同样的,大多数感染了可疑腺病毒的人并没有表现出严重的症状。

The present study investigated the effects of a specific COX-2 inhabitor(NS-398) and a selected PPARγagonist on the proliferation and apoptosis of pancreatic cancer SW1990 cell line to examine whether the two non-celltoxicity agents have synergistic anticancer role, so as to establish the experimental bases for application PPARγagonist associating with specific COX-2 inhabitor in treating pancreatic cancer.

本课题研究特异性COX-2抑制剂NS-398和PPARγ激动剂罗格列酮对人胰腺腺癌细胞系SW1990增殖、凋亡的影响,旨在明确两种非细胞毒性药物对胰腺癌有无协同抗癌作用,为临床联合应用特异性COX-2抑制剂和PPARγ激动剂防治胰腺癌提供实验依据。

In vivo gene therapy of ovarian cancer by adenovirus-mediated thymidine kinase gene transduction and ganciclovir administration.

羟甲基无环鸟苷对携有单纯疱疹病毒胸腺嘧啶核苷激酶基因人卵巢癌裸鼠皮下移植瘤生长的抑制作用。

Antibiotic treatment of bubonic plague is usually effective, but pneumonic plague is difficult to be treated and even with antibiotic therapy death often occurs.

抗生素治疗一般对腺鼠疫有效,但难以治疗肺鼠疫,经常有抗生素治疗仍死亡的情况发生。

She had had an adenoidectomy at the age of 10 years.

她有一个腺样体切除术10岁的时候。

Moreover, Fyn kinase directly phosphorylated LKB1 on tyrosine 261 and 365 residues, and mutations of these sites resulted in LKB1 export into the cytoplasm and increased AMPK phosphorylation.

这是&能量主开关&磷酸化腺苷酸活化蛋白激酶在它们脂肪和肌肉组织中含量较少的结果。这些发现显示,这种酶有可能帮助开发一种减肥新药。

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On the other hand, the more important thing is because the urban housing is a kind of heterogeneity products.

另一方面,更重要的是由于城市住房是一种异质性产品。

Climate histogram is the fall that collects place measure calm value, cent serves as cross axle for a few equal interval, the area that the frequency that the value appears according to place is accumulated and becomes will be determined inside each interval, discharge the graph that rise with post, also be called histogram.

气候直方图是将所收集的降水量测定值,分为几个相等的区间作为横轴,并将各区间内所测定值依所出现的次数累积而成的面积,用柱子排起来的图形,也叫做柱状图。

You rap, you know we are not so good at rapping, huh?

你唱吧,你也知道我们并不那么擅长说唱,对吧?