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Results: The most common locations of PIP were at the margin of both lower lobes and associated with local pleural thickening and adhesion. The density of nodule in which CT attenuation value was 15~60 HU (26.9±13.5HU) was lower than that of PLC. Most of them were round/round-like and irregular in shape. The interior density of lesion was inhomogeneous. The presence of calcification or multiple cavitations, straight margin sign, hole sign and without hilar and mediastinal adenopathy were of great significance in the diagnosis of such kind of disease.

结果:炎性假瘤多位于两肺下叶,邻近胸膜增厚、粘连,病灶密度偏低(平扫CT值15~60HU,平均26.9±13.5HU),与周围型肺癌比较有统计学差异,其形态以圆形/类圆形和不规则形多见,病灶内密度多不均匀,可见钙化及多发空洞,边缘呈平直状、周围见毛玻璃样改变及肺门纵隔无淋巴结肿大等征象对本病的CT诊断有意义。

The main performance characteristics of the observation group were restrictive lung function damage to dysfunction of pulmonary ventilation.

肺功能异常的检出率,观察组与对照组之间的差异有统计学意义(χ^2=38.07, P.01),主要表现为观察组肺功能损害特征以限制性肺通气功能障碍为主。

The results suggest that TP can inhibit lung tumorogenesis caused by estrogen and urethan and that TP will be of great significance in preventing lung tumor.

结果提示茶多酚对药物联合诱导的肺肿瘤发生有抑制作用,在肺肿瘤预防上有重要意义。

Methods Sonographic charactistics of 133 cases with pleural or pulmonary diseases were analyzed retrospectively,and the results were compared with those of chest X-ray film,including 107 cases of tuberculous pleurisy,21 cases of malignant tumor of lung and pleura,1 case of lobar pneumonia,2 cases of inflammatory pseudotumor and 2 cases of hemopneumothorax.

结果 129例(97%)有胸腔积液,表现三类型。21例肿瘤病例中14例(67%)发现肿块,1例中心型肺癌和1例大叶性肺炎呈肺实变表现,类似肝脏声像图表现,血气胸有外伤史,39例(29%)B超漏诊肺内同时存在的病变。

Results There were all 129 cases(97%) with hydrothorax,which showed as 3 types.14 cases (67%) from 21 cases of tumor were found with lumps;1 case of central type of lung cancer and 1 case of lobar pneumonia had shown an appearance of consolidation of lung and the similar sonographic appearance to liver;the cases of hemopneumothorax the medical record of surgical trauma.

结果 129例(97%)有胸腔积液,表现为三种类型。21例肿瘤病例中14例(67%)发现肿块,1例中心型肺癌和1例大叶性肺炎呈肺实变表现,类似肝脏声像图表现,血气胸有外伤史,39例(29%)B超漏诊肺内同时存在的病变。

Results:31 cases (34.8%) had bronchovascular shadows with the small spot shadows;32 cases (35.9%) had clouded shadows;26 cases (29.2%) had patchy shadows and pulmonary cyst; We also can find pneumothorax, hydropneumothorax, mediastinal emphysema, subcutaneous emphysema, fracture of costal bone.

结果:肺纹理有改变伴有小斑点状阴影31例(34 8%);出现云雾状及磨玻璃状阴影32例(35 2 %);有大片模糊的较高密度影和肺囊肿影2 6例(2 9 2 %);另外还发现气胸、液气胸、纵隔气肿、皮下气肿及肋骨骨折等。

Results:31 cases (34.8%) had brochovacular shadows with the small spot shaows;32 cases (35.9%)had clouded shadow; 26 cases (29.2%) had patchy shadows and pulmonary cyst ;We alse can find pneumothorax,hydropneumothorax,mediastinal emphysema,subcutaneous emphysema,fracture of costal bone.

结果:肺纹理有改变伴有小斑点状阴影37例(37%);出现云雾状及磨玻璃状阴影48例(48%);有大片状模糊的较高密度影和肺囊肿15例(15%);另外还发现气胸、液气胸、纵隔气肿、皮下气肿及肋骨骨折等。

Although the pathogenesis is not very clear, new understandings about development of pulmonary fibrosis has appeared in company with impenetration of cell biology research and molecular biology research. In a word, research of pulmonary fibrosis gradually appears to be integrated and multidisciplinary crossover.

尽管肺纤维化发病机制目前尚不完全清楚,但随着细胞生物学和分子生物学研究不断深入,对肺纤维化的发生、发展机制有了许多新得认识,肺纤维化机制的研究正逐渐走向整体化和多学科交叉方向。

Finally, we established rat model of PF induced by bleomycetin, and observed the interventional action of phenol total base to model. The analysis of experimental result including pathematologic and tissue biochemical indicator showed phenol total base of plumula nelumbinis have some therapeutic action to rat model of PF induced by BLM.

通过病理学观测及组织生化指标的检测(SOD、MAD、GSH一PX、Hyp),说明莲子心酚性总碱对博莱霉素致大鼠肺纤维化有一定治疗作用,可能的作用机制:降低肺纤维时胶原含量;抑制肺成纤维细胞的增殖;抗自由基和抗脂质过氧化作用及提高了机体内GSH一Px含量。

Imaging from micro-CT of rats could reflect radiologic changes of pulmonary fibrosis in different stages.Sign of linear opacities is a mark which suggests the formation of moderate or severe pulmonary fibrosis and sign of bullae or pneumothorax is a cue of the formation of severe pulmonary fibrosis.

Micro-CT能显示大鼠PF不同阶段的影像学改变,线状影可作为鉴别Ⅱ~Ⅲ级肺纤维化形成的标志,肺大泡或气胸对Ⅲ级肺纤维化形成有提示作用。

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