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Unusual findings included lobar consolidation, hilar adenopathy, cystic lesions, pleural effusion and atelectasis, etc.

少见的表现有大叶实变、肺门淋巴结增大、肺囊性病变、胸腔积液及肺不张等。

The positive expression both of p14ARF and mtp53 protein in NSCLC tissues were significantly different from that in nonmal lung tissues and tissues adjacent to the cancer (P.01).The expression of p14ARF protein was correlated with pathological degree(P<0.01),but it was uncorrelated with pathological staging,lymphaden metabasis and vessel invasion(P>0.05).The expression of mtp53 protein was correlated with clinical pathology staging,pathological degree and vessel invasion(P<0.05 or P<0.01),but it was uncorrelated with lymphaden metabasis(P>0.05).(2) The coexpression of p14ARF and mtp53 was 36.7%,their consistency was 38.8%,but the expression of p14ARF protein were negatively correlated with the expression of mtp53 protein(r=-0.3553,P<0.001).Conclusion The results suggest that the decrease of p14ARF and the increase of mtp53 protein may play an important role in the genesis and development of NSCLC.

结果 (1)在正常肺组织、癌旁组织和NSCLC中p14ARF蛋白的阳性表达率分别为93.3%、83.3%、55.1%,mtp53蛋白的阳性表达率分别为6.7%、44.4%、79.6%;p14ARF蛋白和mtp53蛋白在NSCLC中的表达与正常肺组织和癌旁组织比较均有显著性差异(P<0.01);p14ARF蛋白表达与临床病理分期、有无淋巴结转移、有无脉管浸润无关(P>0.05),而与病理分化程度有关(P<0.01);mtp53蛋白表达与临床病理分期、病理分化程度(P<0.01)及有无脉管浸润(P<0.05)有关,而与有无淋巴结转移无关(P>0.05);(2)在NSCLC中,pl4ARF与mtp53蛋白共表达为36.7%,一致性为38.8%,二者表达呈负相关(r=-0.3553,P<0.001)。

The DGGO had centrally distributed with lobular central node, acinose node or mass. 26 cases were the diseases with abnormity of extravascular fluid overload, including 21 cases' pulmonary edema and 5 cases' contusion of lung. The DGGO had distributed pulmonary pendulous region or relative pendulous region.

以肺内血管外体液量增加为主的疾病有肺水肿21例及肺挫伤5例,肺水肿性磨玻璃影具有沿下垂部分布的趋势,可伴有心影增大及胸腔积液;而肺挫伤性磨玻璃影与外伤部位相关,且在外伤区肺内也具有沿下垂部分布的趋势。

Results: we estalished ideal copd models in stort time. there existed the expression of nos in both the normal lung tissue and the lung tissue of copd,mainly orienrared in the cytoplasm of cell.the immunohistochemical result indicated that inos increased significantly ,in comparison with the control group, in bronchiolar mycoderma epithelial and enos remakably decreased in pulmonary blood vessel.

结果:联合应用烟熏和ppe在较短的时间内建立了较理想的copd模型;一氧化氮合酶在正常肺组织与copd的肺组织均有表达,主要定位在细胞浆内;免疫组化结果表明模型组inos在支气管黏膜上皮呈强阳性表达,肺血管enos表达明显减弱,与健康对照组比较有显著性(p.01)。

The intersegmental veins can be considered as the main tributary of pulmonary segmental veins and it commonlly located in the inferior, interior and posterior side of the corresponding segmental bronchi.

肺段动脉与支气管紧密伴行,并有基本一致的分支和分布,多位于支气管的上、外或前方;肺段静脉不与支气管分支一致,可分段内支与段间支,后者可视为肺段静脉的主干,多位于肺段支气管的下、内或后方。

The Western blot results were consistent with those of immunohistochemical method. CONCLUSION: p38 MAPK expression increases in alveolar and airway epithelial cells in LPS induced acute lung injury rat models. The activation of p38 MAPK is found in most lung tissues, suggesting that p38 MAPK participates in the signal transduction in inflammatory and noninflammatory cells.

LPS诱发的大鼠急性肺损伤模型中,磷酸化p38 MAPK在气道和肺组织内表达增加,p38 MAPK的激活见于肺组织内多数细胞,提示肺内炎性和非炎性细胞均有p38 MAPK信号分子的激活。

Result: A 77-year-old female presented at our hospital for blurred vision in her right eye. The intraocular pressure was 46 mmHg and slit lamp examination showed a protruding mass with papillomatous appearance near pupil margin. On chest X-ray examination, only prominent left hilum was noted. Iris tumor excisional biopsy was performed. Pathology investigation of the surgical specimen revealed carcinoma and immunohistochemical study demonstrated thyroid transcription factor-1 (TTF-1) positive. Chest-computed tomography showed left upper lung tumor and primary pulmonary adenocarcinoma was confirmed after CT-guided biopsy. She was placed under treatment with Genfitinib. Recurrent iris tumor mass was noted during follow-up, and chest CT revealed shrinkage of adenocarcinoma.

结果:一位七十七岁女性因右眼视力模糊至本院就诊,当时眼压为46毫米汞柱,细隙灯检查发现虹膜靠近瞳孔边缘有一乳突状肿块,胸部X光摄影仅见左肺门稍明显并未发现明显病灶,患者接受虹膜肿瘤切除手术,病理报告显示为恶性肿瘤,且免疫组织染色为thyroid transcription factor-l阳性,进一步的胸部电脑断层显示左上肺肿瘤,经电脑断层指引之切片检查证实为原发性肺腺癌,她接受Genfitinib药物治疗,后续追踪发现虹膜肿瘤复发,胸部电脑断层扫描显示肿瘤体积缩小。

Methods 36 pulmonary tuberculosis patients who had operative indications were treated by video-assisted thoracoscopy combined with chest minimal incision surgery,including 18 cases of pulmonary wedge resection, 15 cases of pulmonary lobectomy and 3 cases of compound pulmonectomy.

方法对36例有手术指征的肺结核患者运用电视胸腔镜辅助小切口进行肺切除术,其中肺楔形切除术18例、肺叶切除术15例、复合肺切除术3例。

Results The respiration dysfunction caused by oil acid could be prominently improved by ulinastain. There was only a little expression of hemeoxygenase-1 in the lung of Group A, but the expression increased in Group B and significatively increased in Group C.

结果:乌司他丁能显著改善油酸所致急性肺损伤所致的呼吸窘迫;肺组织血红素氧化酶-1在对照组仅有少量表达,急性肺损伤组表达增多,乌司他丁干预组表达明显增强。

Methods Before the total correction of TOF was performed, the collateral arteries were transcatheter closured in 3 cases with huge aorta pulmonary collateral arteries (2 cases with PDA occluder, 1 case with coil).

术前介入治疗:3例有巨大体肺侧支的重症TOF在根治术前予以侧支血管堵塞术,其中2例采用国产动脉导管未闭封堵器堵闭体肺侧支血管,1例采用可控弹簧圈栓塞体肺侧支血管。

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