有病毒的

First, after contracting flu, has the complication risk high crowd, including 6 months to 5 year-old babies and infants; 60 year-old above old person; Contracts the chronic pulmonary tuberculosis, cardiovascular illness to get sick, the nephrosis, the liver disease, the nosohemia or the metabolic illness get sick the adult and the child; Has the immunosuppression condition adult and the child, including because of takes immunosuppression which the medicine or the AIDS virus infection cause; Contracts the adult who and the child for a long time nervous system illness gets sick (for example cognition barrier, spinal cord damage, epilepsy or other nerve muscle illness sickness and so on); Accepts the aspirin treatment for a long time child and young people (6 months to 18 years old); Lives for a long time in the home for the elderly, the sanatorium and other chronic illness sickness nursing organization personnel; Preparation female who is pregnant in flu season.

一是患流感后发生并发症风险较高的人群，包括6个月到5岁的婴幼儿；60岁以上的老人；患有慢性肺病、心血管疾病、肾病、肝病、血液病或代谢性疾病的成人和儿童；有免疫抑制状况的成人和儿童，包括因服用药物或艾滋病病毒感染而导致的免疫抑制；长期患有神经系统疾病的成人和儿童(如认知障碍、脊髓损伤、癫痫或其他神经肌肉疾病等)；长期接受阿司匹林治疗的儿童和青少年(6个月到18岁)；长期居住在敬老院、疗养院和其他慢性疾病护理机构的人员；准备在流感季节怀孕的女性。

Second, residues in the reactive site of the inhibitor were replaced by the consensus substrate recognition sequence of furin, namely, Arg at P_1, Lys at P_2, Arg at P_4 and Arg at P_6. In addition, the P_7 residue Asp was substituted with Ala to avoid possible electrostatic interference with furin inhibition. Finally, the extra N and C terminal residues beyond the doubly conjugated disulfide loops were further truncated. However, all resultant synthetic peptides were found to be temporary inhibitors of furin and kexin during a prolonged incubation, with the scissile peptide bond between P1 and P'1 cleaved to different extents by the enzymes.

高活性、低分子量的furin酶抑制剂有可能发展成为新型的抗细菌内毒素和抗病毒感染的药物，我们以绿豆胰蛋白酶抑制剂Lys片段长链22肽为模板，设计了一系列能抑制furin和kexin活性的突变体，采用如下三种方法逐步优化：一、去除Lys片段长链三对二硫键中的一对，用Ser替换Cys，减少可能存在的二硫键错误配对；二、抑制剂的活性中心根据furin底物的专一性逐步改变，即P1、P2、P4和P6位分别变为Arg、Lys、Arg和Arg，同时为了避免P7 Asp和P6 Arg之间可能存在的相互作用，将P7位Asp替换为Ala；三、将两对二硫键形成的双环的外面5个氨基酸残基去除。

To prevent such an outbreak from happening, it is imperative that administrators refrain from logging onto a suspect machine using their own accounts. Logging on using the workstation's local administrator account can also have the same effect; most corporate workstations are ghosted from the same image and could have the same local admin account and password.

要防止此类病毒爆发事件的发生，紧急的办法是不要实用管理员自己的用户名和密码登陆系统，用工作站的本地管理员用户一样也会有此类事件发生，很多的工作站的系统都是通过同一个镜像文件并利用ghost方式进行的安装，因此用户名和密码相同也是肯定的

MethodsThe activity of macrophage cell in abdomen cavity and NK cell in spleen and the SIgA contents in saliva were detected, and the survival rate of mice which had been infected by influenza virus FM 1 were observed after the powder of Le IFN α/supplement material mixture had been insufflated in mice buccal cavity.

一些研究表明，人体的干扰素受体，主要分布在口腔、腭咽及鼻腔黏膜部，只要少量的IFN同上述部位的受体结合，即可发挥IFN的生物活性[1] ，同时也有不少以人的αIFN通过口腔途径给药用于抗病毒和免疫调节的动物实验[2 ] 。

The rate of other index overpassed rearranged objectives. Of which, the rate of VCT was 111.45%, the rate of receiving anti virus treatment was 108.42%, the rate of programs activities of government and non-government was 133.83%. At least there was one teacher trained living skills about AIDS. The fulfilling rate of the number of middle schools of developing living skill education about AIDS was 125.73%. The fulfilling rate of the number of middle school students educated about living skills was 147.53%.

其中自愿咨询检测人次数的目标完成率为111.45%；接受抗病毒治疗的艾滋病患者数的目标完成率为121.37%；获得关怀与支持的HIV感染者／艾滋病患者及其家庭数的目标完成率为108.42%；政府部门与非政府机构主动开展的项目活动数的目标完成率为133.83%；至少有一位教师接受过艾滋病生活技能培训，并对中学生开展艾滋病生活技能教育的中学数的目标完成率为125.73%；接受生活技能教育的中学生数目标完成率为147.53%。

objective to assess the fulfillment of round 3 of global fund aids program in china in order to provide basis for selecting scientific preventive measures and making reasonable work plan.methods to analyze the core programs from reports of round 3 of global fund aids program in 72 counties of 7 provinces in mid part of china,and to assess it by combining specific investigated results.results up to dec 31,2006,fulfilling rate of receiving treatment for occasional infection,and the number of preventing aids patients as well as infected persons was 98.57%.the rate of other index overpassed rearranged objectives.of which,the rate of vct was 111.45%,the rate of receiving anti-virus treatment was 108.42%,the rate of programs activities of government and non-government was 133.83%.at least there was one teacher trained living skills about aids.the fulfilling rate of the number of middle schools of developing living skill education about aids was 125.73%.the fulfilling rate of the number of middle school students educated about living skills was 147.53%.conclusion the fulfillment of objective management of round 3 about aids,especially core index was effective.but there existed the problem that fulfilling rate of some index was too high,which would be corrected in the later phase.

对中国中部7个省72个县实施第三轮全球基金艾滋病项目的完成项目指标报表进行汇总，对其中10个核心项目进行分析。结果截至2006年12月31日，10个核心项目中，除接受机会性感染治疗和预防的艾滋病患者/感染者人数的完成率为98.57%，其他指标完成率均超过了预定目标。其中自愿咨询检测人次数的目标完成率为111.45%；接受抗病毒治疗的艾滋病患者数的目标完成率为121.37%；获得关怀与支持的hiv感染者/艾滋病患者及其家庭数的目标完成率为108.42%；政府部门与非政府机构主动开展的项目活动数的目标完成率为133.83%；至少有一位教师接受过艾滋病生活技能培训，并对中学生开展艾滋病生活技能教育的中学数的目标完成率为125.73%；接受生活技能教育的中学生数目标完成率为147.53%。结论第三轮艾滋病项目的目标管理，特别是核心指标的完成情况取得了比较理想的效果，但存在个别指标完成率过高的问题，将在后续阶段予以纠正。

I imagine there might be a world of mutating buildings, living silicon polymers, software programs evolving offline, adaptable cars, rooms stuffed with coevolutionary furniture, gnatbots for cleaning, manufactured biological viruses that cure your illnesses, neural jacks, cyborgian body parts, designer food crops, simulated personalities, and a vast ecology of computing devices in constant flux.

没准儿我们将面临一个世界，其中有变异建筑，活生生的硅聚合物，软件程序脱机进化，还有可修改的车辆、塞满共同进化的家具的房间，打扫卫生的蚊型机器人，能治病的人造生物病毒，神经性插座，生控体系统的身体部件，带标签的粮食作物，模拟个性，以及由不断变化的计算机设备组成的巨型生态。

Antibody-dependent enhancement of dengue virus infection and the unclear pathogenesis mechanism hamper the prevention and treatment of the disease. No efficient preventative and therapeutic drugs are available now, but much progress has been made in the last few years in the drug prevention and therapy of dengue fever.

抗体依赖的感染增强作用以及对病毒致病机制的尚未完全阐明均阻碍了登革热预防与治疗药物的发展应用，目前并无临床可用的特异性预防与治疗药物，但近年来，随着登革热发病机制以及治疗方法研究的不断深入，在登革热药物防治方面的研究有了新进展。

The cancer therapy and composition for using the same of the present invention involves administering a therapeutically effective and non-lethal amount of a pharmaceutical composition to mammals in need of such a therapy and more specifically humans suffering from cancerous neoplasms and to prevent the formation and elimination of the hostile cancer viability zone and more specifically the tumor micro-environment which can help treat metastatic tumors and at sites other than a primary tumor site with site specificity for malignant cells that is not restricted by the type of cancer cell, including damaged or necrotized cells and tissues.

使用本发明制剂的抗癌疗法和制剂可以在需要此类治疗的哺乳动物，更确切一点，受癌瘤折磨的人身上，使用疗效显著、剂量不致命的医药制剂。可以组织敌对癌瘤生存区的形成，并加以消除，更确切一点，消除癌瘤微环境，从而有助于治疗病毒转移性癌瘤；消除当场有针对性地治疗不受癌细胞类型限制的恶性细胞，如受损或坏死的细胞和组织。

These data suggest that the terminal hairpin structure and ITRs of PfDNV play a key role in the rescue and gene correction process: sequence at the junction of the terminal palindrome of PfDNV genome and the pUC119 can form typical Holliday structure, it can be cutted by the special endonuclease, then the exposed 3'hairpin structure serving for a self-primer to initiate viral DNA replication; and the intact extremity acting as a template to repair another altered end within inverted terminal repeats.

说明存在着一种拯救和基因修复机制，推测与PfDNV基因组末端结构（Hairpin、ITR）有密切关系：PfDNV基因组与pUC119质粒连接处可形成Holliday结构而被识别该结构的核酸内切酶所切割，游离下的基因组3'发夹结构作为引物起始复制，然后被置换链的完整的5'ITR作为模板修复部分缺失的另一端ITR，推测这个过程需要病毒NS蛋白以及细胞因子的参与。

Plunder melds and run with this jewel!

掠夺melds和运行与此宝石！

My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

此刻，也许正是在通往天国的路上，我体验着这白色的晕旋。