有影响的

The hypermethylation of 5 CpG in promoter region serves as a mechanism of the inactivation of RASSF1A gene. This mechanism has been widely confirmed in multiple tumorgenesis including prostate carcinoma cell line DU145. Object Our study is to disclose the epigenic mechanism of the carcinogenesis of prostate cancer. Including: 1. We use demethylation agents in combination with chemotherapeutic drugs, to disclose whether demethylation agents can enhance the anticancer effect of chemotherapeutic drugs. 2. to study whether demethylation drugs can affect the methylation level of RASSF1A gene in.

目的 本研究旨在探讨前列腺癌的表遗传学发生发展机制，包括： 1、甲基化抑制剂与多种化疗药物联合应用，探讨二者间的协同作用，增强化疗药物疗效； 2、体外应用甲基化抑制剂对前列腺癌细胞DU145的RASSF1A基因甲基化水平的影响； 3、体外应用甲基化抑制剂对前列腺癌细胞DU145的RASSF1A基因及蛋白表达的影响，以期为进一步深入探索通过改变抑癌基因的甲基化而为前列腺癌发生机制和基因治疗提供有意义的数据和理论依据。

Results: None of 12 recipients developed acute transfusion related hemolysis during infusion of stem cells. Both major and minor ABO incompatibility had no adverse effects on engraftment and recovery of platelets. However, the major ABO-incompatible group showed trends of slower erythropoietic recovery and 1 recipient in this group experienced delayed hemolysis.

结果：12例ABO血型不合的allo-HSCT受者在输入造血干细胞悬液时无1例发生急性溶血和输血相关性溶血，主要不合和次要不合对allo-HSCT骨髓植活和血小板恢复均无影响，但主要不合组红系恢复有延迟的趋势，有1例发生迟发性溶血。

This paper especially discusses the origin and development of accounting behavior,the subject and object of ac- counting behavior,the influenced factor and aim of accounting behavior.Based on these,the essence of accounting behavior is concluded as follows:influenced by the internal and exter- nal environment and prompted by the objective of accounting behavior,it is dynamic and ob- jective accounting practical activity which the subjec...

在讨论了会计行为的产生与发展、会计行为主体和客体及其相互关系、会计行为的目标、会计行为的影响因素及要求后，以此为基础，概括出会计行为的本质——会计行为主体受内、外环境的影响，在会计行为目标的驱动下，运用现代会计管理的理论和方法作用于会计管理客体能动的有目的的会计实践活动。

Some factors, like expression stage in adenovirus and expression level in influenza, is also prominent in some viruses. In HPV and HIV, the hydropathy of the protein also plays its role, although not the main factor.

某些选择因素如腺病毒中基因的表达时相、流感病毒中基因的表达水平是比较明显地影响病毒密码子选择的因素，而在HPV和HIV基因所编码的蛋白的疏水性尽管对于病毒的密码子使用有影响，但不是最主要的因素。

Since the most significant difference happened between the middle phase of expiration and the middle phase of inspiration, this result implies that it is the intrapulmonary pressure and the cardiac volume, but not the relative position of the heart and electrodes, which cause the variation of the amplitude of QRS complex.

在一些情况下需要消除呼吸的影响，如高分辨心电图中的波形对齐［1］。这就要求对呼吸影响QRS波形的机制有深入的了解。有些研究通过数学模拟和观察体表电位图，认为呼吸造成心电图变异的主要原因是由心脏与电极的相对位置改变造成的［2，3］，并据此作了一些补偿方案。

Despite my inventable sadness at the fact of my leaving,I am glad indeed that your time and mine intersected for a period,enanbling me to share my thoughts with you,for what they are worth.

虽然离别无可避免地让我伤感，但我真的很高兴我们的时间有交汇的这一段，这让我和你们分享许多想法——不管它们是否对你有影响。

Secondly, there are bigger value at risk by Historical Simulation Method of risk-factors free, represented investitive net value are NT 10,000,000, maximum loss of 5﹪probability will greater than NT 2,816,827 or NT 2,344,946. So used considering VAR－Bootstrap of risk factors were more appropriated model, because model of considering risk factors were able to accurate estimate reality value at risk.

二、以未考量风险因子之历史模拟法及GARCH－拔靴法所估计风险值较大，表示投资净值一千万，有5﹪的机率可能的最大损失会大於2，816，827元或2，344，946元，因此，考量风险因子之VAR模型－拔靴法为较适当之模型，因有考量影响风险之因子，较能准确估计出实际之风险值。

The molecular weight of dextransucrase measured by SDS-PAGE was 170 kDa ,which was similar to the enzyme from Leuconostoc mesenteroides. The enzyme had an optimum temperature between 25and 30℃ and an optimum pH of 5.4. It was relatively stable in the range of pH 5.0 to 7.0, but the stability declined rapidly as soon as the temperature rose over 35℃.

以蔗糖为底物，酶促反应的最适温度为25～30℃，最适pH值为5.4，动力学常数Km值为10.43 mmol/L；酶活在pH 5.0～8.0较为稳定，在室温（25℃）保藏4 天仍有59%的酶活力，4℃保存7周酶活力仅下降一半，但在35℃以上失活很快；Ca2+对催化作用有较大的促进，Mg2+有微弱的促进作用，K+对催化反应无影响，Cu2+的抑制作用最强。

Most species' populations were decline in last fifty years, especially since the last 1980's, the populations such as Alpine Musk Deer, Przewalski's Gazelle and Red Deer etc. declined dramatically;(5) Desertification and grassland degredation are obviously affected by climate change on macrographic scale, anthropogenic activities is an important driving role for desertification, herbing, land-development and urbanization have majority impact to biodiversity spatial pattern and its loss.

祁连山区动物资源组成成分复杂，总体上缺乏自身特有的种类，哺乳动物区系特点不很突出，既包含了东部黄土高原和东南湿润地区的兽类成分，又不乏青藏高原特有种类，同时还与新疆的动物区系有一定的联系，近50年来尤其自上个世纪80年代以来，多数种类的种群数量呈下降趋势，其中以马麝、普氏原羚、马鹿等物种的数量下降的最为显著；（5）土地沙漠化和草地退化在宏观尺度上受气候因素影响较大，人类活动对荒漠化的加速发展起着重要的驱动作用，尤其是放牧、土地开发和城镇化建设对生物多样性资源减少以及空间分布格局影响较大。

Estrogen can cause fetal congenital heart defects, large vascular malformation, hydrocephalus, cerebral meningocele, visceral malformations, hydrocephalus, meningeal, bulging, visceral malformations, feminization of male fetus, penile deformity , cervical abnormalities, but also easy to cause miscarriage, stillbirth and ectopic pregnancy.

雌激素可引起胎儿先天性心脏缺陷，大血管畸形，脑积水，脑脊膜膨出，内脏畸形，脑积水，脑脊膜，膨出，内脏畸形，男胎女性化，阴茎畸形，宫颈畸形等，还易引起流产，死胎和异位妊娠。2、黄体酮可使妇胎生殖器男性化，出现阴蒂肥大，阴唇吻合等。3、先锋霉素：可通过胎盘屏障碍进入羊水中，对胎儿的安全性有影响。4、如有子宫收缩可引起先兆流产或先兆早产，应去医院请医生处方遵医嘱应用硫酸舒喘灵等舒缓平滑肌收缩的药物直至子宫收缩停止。

I will endeavour to find you some assistance.

我尽力帮你找人帮忙。

At first I only know bruck is the idol of American younglings, afterwards I returned back to Taiwan ,even in Beijing last year ,I saw her poster everywhere, I was so surprised at her charm.

起初我只晓得布鲁克雷德丝是美国少男少女崇拜的偶像，后来回台湾，甚至去年在北京，居然也四处看见她的海报，才惊讶她的魅力之大。