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This study aimed at observing the effect of PingFei Mixture treating cachexia and researching the mechanism of that effect in cytokine level.

研究晚期非小细胞肺癌恶病质的治疗是提高患者生活质量的最直接途径,在延长带瘤生存方面有重要意义。

Seeds mostly glossy black or iridescent gray, less often brown, orbicular-reniform, minute, often tuberculate, without caruncle.

种子多数黑色的或虹彩灰色的有光泽的,较少通常棕色,肾形圆形,小,通常具瘤,没有种阜。

Within the fibroid two cystic areas are seen with minimal blood flow consistent with degenerative changes.

纤维瘤内两处囊性区被发现有符合退行性病变的极小的血流量。

objective:study female the yin false wet you of clinical pathology characteristics and discriminate judgment.method:rightness 69example sufferer of clinical and laboratory check the data carry on analysis.result:pcv and small labium seamy side the most familiar(91.3%) skin external appearance with floss form familiar(62.3%) be located on a roe of fish form a time it;(33.33%)organization pathology show the upper part in the ji layer to fill the air a sex net basket a form empty bubble cell kind change;the acetic acid experiment a rate;(97.17%)human milk head lump virus second type examination feminine gender.conclusion:pcvhave a clinical characteristics of show the zhao, acetic acid of experiment hpv examination have importance value towards discriminate analysis.

目的:探讨女阴假性湿疣的临床病理特点及鉴别判断。方法:对69例患者的临床及实验室检查资料进行分析。结果:女阴假性湿疣及小阴唇内侧最为常见(91.3%)皮肤外观以绒毛状常见(62.3%)位于鱼子状次之(33.33%);组织病理示棘层中上部弥漫性网篮状空泡细胞样改变;醋酸的试验率(97.17%);人乳头瘤病毒亚型检测阴性。结论:女阴假性湿疣具有显著的临床特点,醋酸的试验hpv检测对鉴别分析有重要价值。

The ELISA titre was 1:2000.By cell fusion, 46 hybridoma cell lines were screened,and 10 lines were cloned with limited dilution method.16 lines secreting anti-bFGF monoclonal antibody were been developed, and 2 lines targeted fusion protein. Sensitive ELISA and dot-ELISA for bFGF was developed with this mAb. The detection limit of them were 0.1 ng/well and 0.5 ng/well. The expression level of anti-bFGF mAb by different rebuilt engineering cells were identified by western blot and to direct rebuild recombiment engineering cell. The dose and character of anti-bFGF mAb inhibiting bFGF biology activity were searched by 3T3 cell line. Searching 20 tissue of liver cancer, liver cancer cell lines and general tissue of liver, finding bFGF were highly expressed in tissues of liver cancer and liver cancer cell lines. Affinity chromatography purifying bFGF was set up by mAb binging CNBr-pepharose 4B, and the purification was 95%. We found that the titer of anti-bFGF antibody was very high in serum of neuropathic amyotrophia.

应用细胞融合制备46株杂交瘤,对其中10株进行克隆化,获得bFGF特异单抗16株,2株针对融合蛋白;应用该单抗建立了0.1ng/孔灵敏度的ELISA,0.5ng/孔敏度的斑点ELISA;用Western-blotting鉴别了经改造不同工程菌蛋白表达,指导重组工程菌改造;用3T3细胞培养研究了单抗抑制bFGF生物学活性的剂量和特点;合作研究了20例肝癌、肝癌细胞株和正常肝组织,发现前者bFGF高表达;应用单抗偶联CNBr-sepharose 4B建立了小量免疫亲和层析纯化bFGF,纯度达到95%;发现神经性肌萎缩患者血清中含有高滴度的bFGF抗体,已有10多家单位引用单抗或进行合作。

When MR imaging shows thickening and enhancement of the pituitary stalk and associated leptomeningeal disease as in this case, sarcoidosis is a very strong possibility, along with meningitis, particularly fungal.

结节病为一种不明原因的炎性病变,可以影像多个系统,包括中枢神经系统,女性多见,大于10:1,黑人比白人更多见,15%病人累及中枢神经系统,5%有神经症状,脑神经功能障碍和尿崩症是最常见的神经系统结节病的临床表现,MR改变包括脑膜增厚及强化,孤立性肿块或多发性小,散在的脑膜或实质病变,此例病例中MR图像出现增厚强化的垂体蒂伴有软脑膜病变,强烈提示结节病,伴随脑膜炎尤其是真菌性,通常T2表现为低信号,虽然这些也能够在霉菌病/淋巴瘤/脑膜瘤中看到。

Of the 19 cases,19 fetus were found,MRI confirmed 14 cases considered or suspected as fetal corpus callosum agenesis by US(8 cases are completed agenesis of corpus collosom-CACC,6 cases are partial agenesis of corpus collosom-PACC, and 5 cases had took on autopsy),however 3 cases are mild enlargement of lateral cerebral ventricle and 2 cases are leukodystrophy.In these cases,MRI confirmed a Dandy-Walker syndrome and a lipoma of corpus callosum suspected by US,detect a Dandy-Walker syndrome and a microcephalus made missed diagnoses by US.The fetal corpus callosum and additional cerebral anomalies were shown more clearly on MR T_2-weighted images.

胎儿胼胝体长度与额枕径的比值在24~36孕龄阶段相对较恒定。2、19例孕妇共检出胎儿19个,MRI证实超声疑诊的胎儿胼胝体发育不全14例(完全型胼胝体发育不全8例,部分型胼胝体发育不全6例,有胎儿尸检结果对照者5例),3例为单纯侧脑室轻度扩张,2例考虑脑白质发育不良,合并Dandy—Walker综合征1例,胼胝体脂肪瘤1例,检出超声漏诊合并Dandy-Walker综合征1例及脑小畸形1例。

Berbamine extracted from Chinese herb might be a promising candidate of new drug for clinical anticancer treatment, especially for bcr-abl〓 diseases.

我们认为,从中草药小檗属植物中提取的小檗胺在体外及体内均有显著的抗白血病作用,且抗瘤谱广,有望成为一种新型的广谱抗白血病药物,尤其在bcr/abl表达阳性白血病的治疗中发挥作用。

The results presented in this paper indicated that sodium salt of 3,7-bishemis uccinate of 7-hydroxycholesterol (RS 634) at the dose of 45mg/kg/day (×7,ip) could increase DNA, RNA and protein syntheses in bone marrow cells and protein synthesis in liver,spleen and serum, but no markedly effects on DNA and RNA synthesis in liver and spleen of mice bearing EAC were observed, In the subacute test on rats RS 034 (400mg/kg/day, x30 ip) showed no evident effects on the number of RBC, WBC and the percentage of lym...

本文报告的结果表明7β-羟基胆固醇双琥珀酸单酯钠(RS 024)在有效抗肿瘤剂量下(45mg/kg/day,×7ip)对荷瘤小鼠骨髓细胞DNA、RNA和蛋白质合成有促进作用,对肝、脾的DNA、RNA合成无显著影响,但能促进肝,脾中及血清蛋白质合成。按400mg/kg/day连续给药30天,对大鼠红细胞、白细胞数及淋巴细胞百分率无明显影响。提示该药在有效抗癌剂量下毒性较小,并在一定程度上对免疫功能有增强作用。

Department of Haemotology,Zhongda Hospital,Southeast University,Nanjing210009,China)Abstract:Cytokine induced killeris a new kind of immune cells which have non MHC restric-tion,highly proliferation and cytotoxicity.Their activities are superior to lymphokine activated killer cells.Immunotherapy of CIK cells can significantly improve clinical symptoms,but hardly have any side effects.

摘要] 细胞因子诱导的杀伤细胞(cytokine induced killer,CIK)是一种非MHC限制性的新型免疫活性细胞,其增殖能力强、杀瘤活性高、副作用小,优于淋巴因子激活的杀伤细胞,对于提高患者自身抗肿瘤免疫能力有重要作用。

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It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发,分析对称连杆曲线上鲍尔点的产生条件,提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品,年生产总值3000万美元,产品价廉物美、选料上乘、质量保证,深受国内外客户的青睐

The eˉtiology of hemospermia is complicate,but almost of hemospermia are benign.

血精的原因很,以良性病变为主。