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Efficacy and safety of adalimumab as monotherapy in patients with rheumatoid arthritis for whom preious disease modifying antirheumatic drug treatment has failed.

"早期类风湿性关节炎病人腕关节的MRI可以帮助预测6年时的功能,可能在早期阶段用来制订治疗方案",作者写道,"MRI骨水肿是预测功能最显著的因子,很可能是因为它既有反映关节炎症的能力,又有预测骨侵蚀的能力"。

Results Solid arthrodesis of all surgically fused levels was achieved in 65 of 80 patients, and therefore the overall rate of pseudarthrosis was 19% for the primary procedure.

80个患者中有65个首次手术即取得关节的牢固融合,因此,手术的假关节形成率是19%。

The results show that: This tablet can decrease the rat"s footpad swell induced by Freud"s, inhibit the permeability of the blood capillary in inflammatory joint and decrease the 11-2 level in serum while increasing the rat"s body weight,(2) It can lower the rat"s temperature and the permeability of the blood capillary in inflammatory joint induced by collagen and inhibit the delayed type hypersensitivity,It can lower the stickiness of full blood and the accumulation of erythrocyte obviously inblood stasis model rats,lt can inhibit the formation of hemolysin and decrease the index of carbon granule clearance in mice, It can lower the permeability of celiac blood capillary and inhibit the granulomatous hyperplasia by sc cotton ,It can inhibit the pain induced by acetic acid and raise the pain threshold value of heat stimulation.

结果表明:关络通片能明显降低佐剂性关节炎大鼠左右足趾肿胀度,降低大鼠炎症关节的通透性,抑制其IL-2含量,对大鼠体重增长缓慢有一定的改善作用;能改善Ⅱ型胶原诱导性关节炎大鼠的表征指标及炎症关节的通透性,对其迟发型超敏反应有一定的抑制作用;对血瘀模型大鼠,能显著性降低其全血粘度、血浆粘度、红细胞压积;能抑制小鼠的溶血素抗体生成,抑制小鼠网状内皮系统的吞噬能力,具有一定的抑制机体免疫功能的作用,能抑制小鼠腹腔毛细血管通透性增高,抑制大鼠棉球肉芽组织增生,具有一定的抗炎作用;能抑制小鼠醋酸扭体反应、提高小鼠热板痛阈值,具有一定的镇痛作用。

Results among 15 cases, eight cases of Loose bodies about right keen joint;three cases of left keen joint;three cases of both keen joint ;one case of pilosity dissociates bodies;two cases with joint effusion ;six cases with soft tissue swelling.16-slice SCT with 3D reconstruction demonstrated stereoscopic morphology of normal and lesions clearly with MPR correctly demonstrated details and density ,shape and size of lesions.conclusions Sixteen-slice SCT with 3D and MPR techniques can provide valuable spatial information of diseases in bones and joints of wrist and foot which correlated well with that of pathological anatomy .

结果 15例患者中,右侧膝关节游离体8例,左侧3例,双侧3例,多发游离体1例;其中2例伴有关节积液,6例有关节周围软组织肿胀。16层螺旋CT的3-D图像可清晰显示游离体的立体形态,MPR图像则可以多平面,多角度地观察游离体的大小、形态、密度、位置,对病变显示满意。结论多层螺旋CT重建能提供骨关节病变非常有价值的空间关系信息,其表现接近病理解剖,临床应用价值大,有利于临床医师选择治疗方案、制订手术计划。

Anti-CCII antibody level was higher in experiment group than that in the normal group by ELISA(P.001). Besides, typical arthritis pathology was showed by roentgenography and histopathology.

与正常对照组相比,实验组大鼠脚踝与脚趾均有明显的肿胀;ELISA结果显示:实验组大鼠血清中抗CCII抗体水平较正常对照组明显高(P.001); X线摄片结果和病理学分析结果显示,实验组大鼠的关节呈现典型的RA关节样病变和病理组织学特征。

Storm window units should have weatherstripping at all joints, be made of strong, durable materials, and have interlocking or overlapping joints.

暴风窗口单位应该有风雨所有关节,是强大的,持久的材料,并有联锁或重叠的关节的。

Objective To compare the effects of hip arthroplasty and AO compressive cannular in treatment of the displaced fracture of femoral neck in elderly.Methods From 1995.5 to 2004.11, 78 elderly patients of over 65 years old with displaced femoral neck fracture were operated with hip arthroplasty and AO compressive cannular.

目的 比较人工关节置换术与AO加压空心螺钉术治疗老年人有移位股骨颈骨折的疗效方法将1995年5月~2004年11月我院收治的78例年龄在65周岁以上的有移位的新鲜股骨颈骨折患者进行回顾性研究,将病例分 A、B两组,A组为人工关节置换组,B组为AO加压空心螺钉治疗组。

Although both pain and tear size influence glenohumeral kinematics in symptomatic shoulders, only tear size is an independent predictor of humeral migration

尽管疼痛和撕裂的尺寸影响有症状的肩关节的运动,仅仅撕裂的尺寸可以作为肩关节移位的一个预测指标。

objective to investigate the treatment effect of wolter crook plate on distal clavicle fracture and acromioclavicular dislocation.methods thirty two patients underwent surgical repairs with wolter crook plate.results twenty seven cases were followed up for 12 months.according to karlsson,the excellent result was found in 19 cases;good in 8 cases;poor in 0 case.no complications such as infection,non union,plate failure,or redislocation after removal of the plate was found.conclusion the implant of wolter crook plate provides sufficient stability to allow active shoulder exercises immediately after surgery,which is worthy of clinical practice.

对32例锁骨远端骨折及肩锁关节脱位患者采用wolter钢板内固定治疗。结果本组27例获得随访,平均随访时间12个月,根据karlsson疗效评定标准:优19例;良8例;差0例。未出现感染、骨不连、钢板断裂以及内固定取出后再脱位等并发症。结论 wolter钢板固定能提供足够的生物力学稳定性,可允许患者进行早期功能锻炼,且肩关节功能恢复较好,有一定的临床推广应用价值。

Although the etiology and pathophysiology of LBP during pregnancy are poorly understood, one plausible hypothesis is that causes of LBP in pregnancy are multifactorial (i.e., biomechanical stress on ligaments and joints, muscle fatigue, and the effect of the hormone relaxin on joint laxity), with ≥1 factors dominating in an indiidual case.

尽管对孕期LBP的病因学及病理生理学了解甚少,有一个似乎可信的假说宣称:孕期LBP是多因素引起的(施加在韧带和关节的生物力学上的应力、肌肉疲劳及松弛肽的关节松弛作用),对单个对象来说,有不止一个因素交互作用。

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The objective is to subjugate and discourage the people, because that allows the elite to continue to rule unopposed.

其目的是压制和打击人民的积极性,因为这可以让实权派继续统治不会沦为反对派。

GOD,this is the second time you vanquished me!

天啊,这是第二次你打败了我!

So a kind of strong antagonism permeated in the relations of two countries.

所以两国这一时期的政治关系始终弥漫着一种强烈的对抗情绪。