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Focusing on the PGE enrichment mechanism in the basic-ultrabasic intrusions in the Panxi rift, firstly, through the interpretation of TM photograph, data processing of regional geochemical exploration and geophysical prospecting results of gravity, magnetic force and seism, we analyzed the controlling effect of structure and magmatic movement on the PGE mineralization; Secondly, through the study of volcanic apparatus, petrography, measurement of comprehensive geochemical section, isotope tracing and dating of typical PGE-rich melanocratic rock series, we discussed the sources of the PGE-bearing mafic-ultramafic intrusions and basalts, their timing, evolvement sequences, the geochemical processes of magma crystallization and fractionation, and the relationship between magma evolution and structural development; Finally, through the analysis of PGE and chalcophile elements concentrations in the melanocratic rock series and the contrastive study with the Noril''sk magmatic Ni-Cu-PGE sulfide deposit, its related continental flood basalts and Siberia Traps, we discussed PGE mineralization characteristics and its enrichment mechanisms in the melanocratic rock series in the Panxi rift.

本项目首先围绕川西地区主要的PGE矿床及伴生矿的地质环境和有关的地质构造背景，通过TM卫片解译、区域化探和重、磁及地震物探资料分析，总体把握构造及岩浆活动对PGE成矿的控制作用；然后通过对典型富PGE暗色岩套的火山机构地质构造、岩石岩相学、地球化学、同位素定年和示踪等方面的工作，分析本区基性－超基性含矿岩体与喷出岩之间的成岩物质来源、侵入时代及演化序列，研究该区同一岩浆房分异结晶的地球化学过程及其随构造发展的耦合关系；最后通过对暗色岩套PGE地球化学剖面分析以及与俄罗斯诺里尔斯克陆内裂谷溢流型玄武岩中PGE矿化的岩石－构造环境对比研究，探讨该区暗色岩套中的矿化特点和富集部位及其PGE富集机制。

The conclusions are as follows:(1) Neologisms in each Huayu region can be classified into two major categories:self-originated and others-originated,among which the new-born words are "absolute new words" and the inherited word are "relative new words",and there are also others-originated elements in the morphemic and sense systems of new words;(2) Variation can be seen in the morpheme,formation,building and sense of new words in Huayu regions,besides individuals of new words;(3) Aggregation of current new words and compound words with one common morpheme and a same construction,together with the aggregation of synonyms and that of different senses in polysemies,reflect the relevance of the systems of new words in Huayu regions in their variation;(4) Regular participation of hinting sense of a formation element in forming and building new words is an important way of producing new sense of morpheme,and an important reason for the current emergence of words with more than one new senses;(5) Compared with ordinary words,the productivity of ways of word formation in forming new words both in general and of a particular class will change and new ways of word formation appear in Huayu regions;(6) The semantic collocation of the verbal morpheme of new verbs in a phrase has a great influence on the location of its structural center,and the complex syntactic behaviors of new verbs are related to the different processes of argument integration;(7) The processes of building new words with the same meaning differ in levels of approaches to motivation cognition,perspectives of motivation cognition,morpheme motivation and morpheme expression,etc.;(8) The lexical interaction in Huayu regions results in lexical subsystem intersections of current new words across two,three and four regions.

本文的主要结论是：(1)各华语区新词均可分为&自源新词&和&他源新词&两大类，其中的新生词和传承词分属&绝对新词&和&相对新词&，新词语的词素、词义系统中也含有他源成分；(2)除词语个体外，华语区新词在词素、构词、造词、词义等方面均体现了某种程度的变异：(3)通用词语聚合、同素同构词聚合、同义异形词聚合与一词多义聚合集中反映了各华语区新词语系统在变异中的关联；(4)构词单位经常提示词义参与构造新词是产生新语素义的重要途径，也是当代多新义词现象的重要成因；(5)相对于一般词语，构词方式在新词语中的总能产性和在某一词类中所体现的能产性都有所变化，华语区也产生了新的构词方式；(6)新动词的动素在短语中的语义搭配对结构核心的位置有很大影响，新动词的复杂句法表现与不同的论元整合过程有关；(7)同义新词造词过程的差异包括理据认知途径、理据认知角度、词素理据和词素表达等不同层面；(8)华语区的词汇互动形成了双区、三区和四区通用新词等词汇子系统交集，作为华语核心，普通话所含纳的通用词语多于各区域变体。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病，不管是急性淋巴性白血病或是急性骨髓性白血病，在染色体11q23部位有染色体易位的情况；这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是，单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%；并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且，这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后，而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖，遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以，白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

UV-B radiation decreased significantly thequantity of bacteria,actinomyces and fung.UV-B rediation affected significantly the quantity of azotobacter, nitrobacter,denitrifying bacteria, cellulose decomposing bacteria and phosphate decomposing bacteria,but these effects depended ondevelopmental stages of spring wheat.The population qua...

UV－B辐射能显著降低细菌总数以及放线菌和真菌数量；UV－B辐射对好氧性自生固氮菌、亚硝酸细菌、反硝化细菌、好氧性纤维素分解菌和解磷细菌数量也有显著的影响，但这种影响具有生育期之间的差异，春小麦根际土壤微生物种群数量与土壤营养成分有关。

Medication nonadherence is a growing concern to clinicians, healthcare systems, and other stakeholders because of mounting evidence that it is prevalent and associated with adverse outcomes and higher costs of care.

近年来，药物治疗依从性的缺失逐渐成为大夫，医疗保健系统，以及股东关注的焦点，因为不断增多的证据表明依从性的缺失与不良的后果以及高额的医疗支出有关。

Results Oxygen metabolism abnormality was found after trauma, and it was correlated with ISS, RTS, injured organ or region and number of injured organs, shock, systemic inflammatory response syndrome and respiratory complications. It was more intense in the patients with MODS. There was marked difference in the ratio of change in oxygen metabolism between MODS and NMODS groups. Oxygen deficiency metabolic variables tended to deteriorate in the nonsurvival group. More marked changes in metabolic variables indicated severer organ dysfunction, reaching their peak values before death.

结果 氧代谢水平在创伤后即发生异常，与创伤严重度评分、RTS、损伤器官部位与数量、低血容量性休克、全身炎症反应综合征以及是否并发呼吸系统合并症等有关；并发MODS患者氧代谢水平变化更为明显，与轻伤对照组和NMODS组比较相关氧代谢比值改变差异均有显著性；死亡组乏氧代谢指标常呈持续恶化趋势，其代谢水平改变越显著，预示器官功能损害程度越严重，往往于死亡前达到峰值。

The shorter of interruption duration, the more obvious interruption effects, and this support the motion opponency theroy. 3 The different intervals between priming and target were detected. Due to interruption of blank frame, the shorter interruption elicited positive proming effects, which is consistant with integration of temporal and spatial in the human brain. 4 The negative of the same direction is relationship to visual adaption and visual inertia effects.

本系列实验得到以下主要结果与结论：1插入空白图片，将导致特定运动方向的反转，而对二义的运动没有明显影响，反映了空白图片对正常视觉运动的阻断；2阻断时间越短，导致特定运动方向反转的几率越大，即阻断效应越明显，支持运动知觉对立理论；3考察不同间隔的启动——靶刺激，由于空白刺激的插入，启动——靶刺激间隔较短时引起的正性启动效应，与人脑系统对视觉信号的时间与空间整合和视觉惯性是一致的。4同向运动的负性倾斜效应与视觉适应有关。

The morbidity of penial erectile dysfunction in diabetic patients is five times higher than that in non-diabetic people, which is considered being associated with neural and vascular lesions by persisting hyperglycemia. Some workers at home and abroad have discussed clinically these men's sexual function with diabetes. The earliest description by traditional Chinese medicine was found in WAI TAI MI YAO: Diabetes has three types……when the kidney is involved then may manifest thirst but not drink a lot, edema only in the legs, wasted feet first happened and penial atrophy.

中文题名中药治疗糖尿病性阴茎勃起功能障碍作用机制的临床与实验研究副题名外文题名论文作者卢子杰导师许芝银教授学科专业中医外科学研究领域\研究方向学位级别博士学位授予单位南京中医药大学学位授予日期2002 论文页码总数110页关键词中医证候学糖尿病性阴茎勃起功能障碍降糖起萎合剂馆藏号BSLW /2003 /R277.5 /5 男性糖尿病患者的阴茎勃起功能障碍发病率是非糖尿病患者的5倍，目前认为与持续高血糖所致的神经和血管等病变有关。

The results of the ability of anti-oxidation scavenging DPPH free radical shows that polyhydroxy substituted N-benzoylserotonin derivatives (compound 1-10) have the generally better ability of anti-oxidation than control group, in which the IC50 of compound 1-10 ranges 8.75 to 18.02 μg/ml and the IC50 of trolox is 13.04 μg/ml. The abilities of anti-oxidation of compound 1, 4, 5, 7, and 10 are all better than the control group, trolox. Among all, compound 10 has the best ability of anti-oxidation (IC50 is 8.75 μg/ml). This study also discovers that the ability of scavenging DPPH free radical is strongly related to the number and the position of hydroxyl.

在清除DPPH自由基的抗氧化能力结果显示，相较於对照组水溶性维生素E之IC50值13.04 μg/ml，多羟基取代之N-色洛冬宁苯甲醯胺衍生物（化合物 1 ~ 10），皆具有相当不错的抗氧化能力，十种醯胺化合物的 IC50值介於8.75 ~ 18.02 μg/ml之间，化合物1、4、5、7、10的抗氧化能力效果皆优於对照组水溶性维生素E的IC50值，其中又以化合物10的效果最佳(IC50值8.75 μg/ml)，而清除DPPH自由基的能力发现与羟基的数量及其位置有关。

The Tongfuxingshen liquid proctoclysis can promote the patients in unconscious state to conscious state, and improve the degree of coma and the scores of nervous functional defects,To observe the expression of HSP70, HO-1mRNA and the Cerebral vessels permeability, encephaledema in rat brain after experimental haemorrhagic stroke. Hemorrhagic stroke Sprague Dawley rat model was made by injecting collagenase type Ⅶ and hepathrom stereotaxically, Rats were randomly divided into fake operation group, model group and enema group, take orally group, in three time point (3 days, 5 days, 7 days) we observed the change of cerebral vessels permeability, encephaledema and HSP70 immunohistochemistry, HO-1mRNA hybridization in situ.

结果表明，通腑醒神液直肠滴注较灌胃起效快，能尽快促使昏迷患者神志清醒，意识清醒时间平均为4.94天，而灌胃组为6.9天，经统计学处理有极显著性差异；明显改善患者的昏迷程度，第8天治疗组Glasgow-Pittsburgh昏迷评分值平均为29.39分，对照组为26.60分，经统计学处理有极显著性差异；治疗后14天临床疗效比较，通腑醒神液直肠滴注组总显效为54.84%，总有效率为80.65%，而灌胃组总显效为43.33%，总有效率为66.67%，经统计学处理无差异性，可能为样本量过少有关，尚需进一步增加样本量评估。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐