晶状体囊

Objective: Approach the method of posterior chamber intraocular lens implant and suture throught microincision in the complication of phacoemulsification and in the aphakic eye postcataract.

目的：探讨小切口后房型人工晶状体植入并缝线固定术在白内障超声乳化术中后囊膜破裂及白内障术后无晶状体眼中的应用。

During a postoperative healing period following surgery, the anterior capsular remnant fuses to the posterior capsule of the bag by fibrosis (30) about haptics (36) on the implanted lens while the ciliary muscle is maintained in its relaxed state by a cycloplegic to prevent dislocation of the lens, and the lens is deflected rearwardly by the fibrosing anterior capsular remnant to a distant vision position against the elastic posterior capsule (24) of the bag in which the posterior capsule is stretched rearwardly.

在手术后的治愈期间，当睫状肌被睫状肌麻痹剂维持在其舒张状态时，植入晶状体上的触觉连接件（36）周围的纤维化（30）使前囊残边熔结到囊袋的后囊上，以防止晶状体错位。晶状体在纤维化的前囊残边作用下克服囊袋弹性后囊（24）而向后偏移到一个远视觉位置，在该位置上，后囊被向后拉伸。

RESULTS: There were significant differences in capsular opacification occurrence rate and degree between group 1 and group 2. The difference was also associated with surgical methods and lens types.

结果：单纯摘除组与人工晶状体植入组，人工晶状体植入中，不同的手术方法及不同的人工晶状体类型其后囊膜混浊发生的频率及程度均存在较大差异。

Methods Advanced generation silicone IOL was implanted with injector in group A (102 eyes) and the PMMA IOL, implanted in group B (108 eyes) as the control. The changes of visual acuity, corneal astigmatism, anterior chamber flare, corneal edema, location of IOL, pos terior capsular opaqueness and other operation complications were observed.

对白内障超声乳化吸除术102眼行新一代硅胶推注式人工晶状体植入术，108眼行PMMA人工晶状体植入术；并对两组患者术后视力、术前术后角膜散光、术后前房闪辉、术后角膜水肿、人工晶状体位置、后囊混浊的变化及其它手术并发症进行观察。

Results The rupture of posterior capsule, broken ciliary zonule, prolapse of vitreous during surgery trauma after surgery, type and material of intraocular lens were mainly causes of posterior chamber IOL dislocation. Pupillary dilatation with 1% tropicamide was achieved on 2 of 23eyes, Simple-replace of the IOL was performed succesfully on 10 eyes, anterior IOLs were implanted on 4 eyes, posterior IOLs were implanted on 4 eyes, and the IOL was removed on 3 eye.

结果 手术中后囊膜破裂、悬韧带离断、玻璃体脱出、手术后外伤及人工晶状体的材料和类型是后房型人工晶状体脱位的主要原因。23眼中2眼用1%托吡卡胺扩瞳后自行复位；10眼单纯手术复位成功；4眼更换前房型人工晶状体；4眼更换后房型人工晶状体；3眼取出人工晶状体后未再植入。

RESULT: 1.Ouabain act on lens sodium-pump,under the LM,lens anterior capsular membrane discontinuous,epithelium cells clustered,occluding zonule seperated,lens fiber layers fractured.Under the EM,cells totally hollowed,mitochondria swelling,myelin figure appeared.RT-PCR examine the expression condition of αsubunit of sodium pump on mRNA level,α1、α2 and α3-isoform are all decreased.2.Digoxin act on lens sodium-pump,under the LM,lens cell oedema,linkage distructed,extensive exfoliation.Under the EM,plasma appeared little half-transparant hollow region,mitochondria swelling and ridge disappeared. RT-PCR examine,α1、α2 and α3-isoform are all decreased.3.Amphotericin B act on lens sodium-pump,under the LM,lens epithelium cells linked tightly,arranged in-line,lens fiber layers arranged tightly and regularily.Under the EM,abbundant cellular organes,exuberant cells function indicated. RT-PCR examine the expression condition of αsubunit of sodium pump on mRNA level,α1 and α3-isoform are increased significantly,demonstrated isoform-specific action.4D-thyroxine act on lens sodium-pump,under the LM,lens plasmalemma integrated,cells arranged tightly and regularily.Under the EM,nucleus fission appeared,desmosome half-desmosome and tensile microfilaments linked the cells. RT-PCR examine,α2 and α3-isoform are increased, also demonstrated isoform-specific action.5.Vitamin E act on lens sodium-pump,under the LM,lens anterior capsular membrane continuous and smooth,epithelium cells tightly linked,lens fiber layers appearede hollow region occasionally.Under the EM,lateral membrane high density belt appeared,abundant nucleolus. RT-PCR examine,onlyα1-isoform are increased, demonstrated significantly isoform-specific action.6.DMSO act on lens sodium-pump,under the LM,lens anterior capsular membrane slightly thicker,cells linkage partly distructed.Under the EM,plasmalemma denaturation,mitochondria swelling.RT-PCR examine,α1、α2 and α3-isoform are all altered slightly and haven't significant meanning.

结果：1、哇巴因作用于晶状体钠泵后，光镜下晶状体前囊膜断裂、上皮细胞聚积、闭合连接分离、纤维板层裂隙，电镜下全层细胞空泡化、线粒体肿胀出现髓样结构，RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达均减弱。2、地高辛作用于晶状体钠泵后，光镜下晶状体细胞水肿、细胞连接破坏、广泛剥离，电镜下胞质见少许半透明空化区、线粒体肿胀嵴消失，RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达均减弱。3、两性霉素B作用于晶状体钠泵后，光镜下晶状体上皮细胞紧密连接、线状排列、纤维板层紧密规整，电镜下细胞器丰富、细胞功能旺盛，RT-PCR法检测α1及α3表达显著增强、具有一定的重整异构作用特异性。4、D甲状腺素作用于晶状体钠泵后，光镜下晶状体质膜完整、细胞排列紧密规整，电镜下胞核见分裂像、细胞间有桥粒、半桥粒及张力微丝，RT-PCR法检测α2及α3表达均增强、亦有一定的重整异构作用特异性。5、维生素E作用于晶状体钠泵后，光镜下晶状体前囊膜连续光滑、上皮细胞紧密连接、纤维板层偶见空化，电镜下囊侧膜内有高电子密度带、细胞核仁丰富，RT-PCR法检测仅有α1的表达显著增强、具有极强的重整异构作用特异性。6、二甲基亚砜作用于晶状体钠泵后，光镜下晶状体前囊膜轻度增厚、细胞连接部分破坏，电镜下质膜变性、线粒体肿胀，RT-PCR法检测晶状体钠泵α亚单位α1、α2及α3三种重整异构体在mRNA水平的表达无显著改变。

4Histological examination of the capsular bags: It could be seen in group 4 that a small amount of LECs at the capsular equator proliferated and migrated to the posterior capsule, forming a thin soemmering ring in the periphery of the capsular bags, forming thin fibromembrane which embodied monolay metaplastic fibroblast-like cells in the center of the capsular bags, or with no cells or cortical material in the center of the capsular bags.

囊袋组织学检查：HSV-TK+GCV组可见少量赤道部晶状体上皮细胞(lens epithelial cells， LECs)增殖并向后囊膜迁移，在囊袋外周部形成稀薄的soemmering环，在中央部无细胞和皮质，或仅形成单细胞层纤维膜。

Methods 16 epithelials of lens anterior capsules of diabetic senile cataract were divided into two groups,15 were stained with HE and examined with light microscopy.1 was examined with transmissional electron microscope. The same examination in 16 epithelials of lens anterior capsule in senile cataract was carried out.

收集16例糖尿病患者的老年性白内障眼的晶状体前囊膜上皮分为两组，15例进行HE染色，光学显微镜观察，1例制片电镜观察；对照组取16例老年性白内障眼的晶状体前囊膜上皮分为3组，15例进行HE染色，光学显微镜观察，1例制片电镜观察。

With the innovation of the intraocular lens design, the researches to reduce PCOs after phacoemulsification with transplanting the IOLs attracts the oculists' attention and causes some progresses which express in the new IOLs' design improving the quality of capsular bend formation.

目前，通过人工晶状体（intraocular lens，IOL）设计的革新，以减少白内障超乳联合人工晶状体植入手术后后囊混浊的研究是令人瞩目的，并已经取得一些进展，这主要表现在新的人工晶状体设计改善了囊袋弯曲结构的品质。

Incision into a capsule, especially that of the crystalline lens of the eye, as to remove cataracts by surgery.

囊切开术，晶状体切开术指被膜或囊的切割，尤指眼球晶状体的切割，如通过外科手术摘除白内障

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。