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The present study provides the first autoradiographic evidence of age-dependent regional changes in the density of serotonin (5-HT) transporters in offspring following prenatal exposure to fluoxetine.

放射自显影研究:孕期暴露于氟西汀引起大鼠后代脑5-羟色胺转运体的位点和年龄相关的改变。

The changes of density of epidermal keratinocyte and the amount and distribution of melanin in the epidermal KC were observed by histological, histochemical and autoradiographic techniques.

为了观察全厚皮片移植对过度色素沉着的影响,用豚鼠作实验对象,采用组织学、组织化学及放射自显影技术,观察豚鼠表皮内角朊细胞的密度、角朊细胞内黑色素颗粒的数量及分布形式的变化。

Autoradiographic studies have demonstrated that adenosine A1 and A2 receptors are expressed in the spinal dorsal horn, both on the post-synaptic SG neurons and the central terminals of the primary afferent neurons.

放射自显影的结果表明A_1和A_2受体都分布在脊髓背角,包括突触后SG神经元和初级传入神经元的中枢突,而A_1受体集中分布于胶状质。

The present study proides the first autoradiographic eidence of age-dependent regional changes in the density of serotonin (5-HT) transporters in offspring following prenatal exposure to fluoxetine.

放射自显影研究:孕期暴露于氟西汀引起大鼠后代脑5-羟色胺转运体的位点和年龄相关的改变。

The quantitative autoradiographic 2-(14C)-deoxy-D- glucose methods were used to assess the local cerebral glucose utilization in 46 brain structures in rats suffering from heatstroke.

利用2-(14C)-去氧葡萄糖自动放射显影定量法,分析了大白鼠热中风后脑部46个神经核的葡萄糖代谢率。

At the same time, intracellular DNA was extracted and subjected to Southern blot, hybridized with a ~(32)P-labeled HBV probe and autoradiographed. The intensity of the autoradiographic bands was quantitated by densitometric scans of computer and ED_(50) was calculated.

然后以2.2.15细胞培养为基础,用不同浓度的β-L-D4A进行干预后,经ELISA检测上清液中HBsAg及HBeAg的含量,提取病毒DNA后进行Southern印迹、~(32)P标记HBV探针杂交、放射自显影,经计算机图像处理进行定量分析,求出50%抑制的药物浓度,即EC_(50)。

Results:β-L-D4A was successfully synthesized and confirmed by IR, NMR and MS. Autoradiographic bands showed similar for supernatant and intracellular HBV DNA. Episomal HBV DNA was inhibited in a dose-dependent manner. EC50 of 3 -L-D4A was 0.2 μM. The experiment of cytotoxicity gained its IC_(50) 200 μM.

结果经一系列步骤合成的化合物β-L-D4A经红外光谱、质谱和核磁共振谱鉴定正确;2.2.15细胞培养上清液病毒DNA的Southern印迹、自显影结果显示药物对病毒的抑制呈明显的浓度依赖性,计算出EC_(50)为0.2μM;细胞毒性实验显示IC_(50)为200μM。

The localization of the S-labelled AVP4-8 binding sites in the rat hippocampus was studied by using autoradiographic approach via observing the selective damages of hi_p-pocampal neurons by neurotoxins,and the developmental regulation of the hippocampalAVP4-8 receptor by pretreatment with exogenous AVP4-8 was observed.

本文利用放射自显影方法结合神经毒对海马神经元的选择性损毁观察AVP4_。结合点在大鼠海马内的分布和定位;利用外源性AVP,_a对新生大鼠的处理,观察海马AVP4_。

Using a 3H-labelled 7.3kb fragment of 18S and 28S rRNA g enes as a probe and by chromosomal in situ hybridization,it was demonstrated tha t the autoradiographic silver grains to be located along entire p+ part of the m arker chromosome.

应用3H标记的7.3kb长的rRNA基因探针进行染色体原位杂交,自显影银颗粒沿整个p+区域分布,p+上的银颗粒数是正常近端着丝粒染色体短臂上银颗粒平均数的5倍。

Silver behenate nanocrystals exhibit higher properties, such as sensitivity and maximum density than microcrystals for thermographic or photothermographic systems.

在热敏和光敏感热显影体系,纳米级山嵛酸银晶体比微米级山嵛酸银晶体表现出更高的感光度和影像密度。

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