显像剂

On the basis of the avidity of lesional macrophages for polysaccharide-containing supramolecular structures such as nanoparticles, we have developed a new positron emission tomography agent with optimized pharmacokinetics to allow in vivo imaging at tracer concentrations.

基于病变巨噬细胞和含多糖的超分子结构，如纳米颗粒的亲和性，我门研发出一种新的PET显像剂，该显像剂具有最优化的药代动力学，在示踪浓度时可在体显像。

Methods: TOCA was labeled with (superscript 99m)Tc using HYNIC as bifunctional chelator, EDDA and trieine as coligand. The nude mice bearing human small cell lung cancer underwent static whole body planar imaging after the injection of (superscript 99m)Tc-HYNIC-TOCA or (superscript 99m)Tc-P829. ROIs were drawn and the radioactivity ratios of target to non-target were calculated in every planar imaging. The dynamic biodistribution study was operated in Kunming mice and the percent uptake ratios of two imaging agents in different tissue at different time were measured.

以HYNIC为双功能螯合剂(bifunctional chelator， BFC)，乙二胺－N，N'-二乙酸和三甲基甘氨酸为协同配体进行TO-CA的(上标 99m)Tc标记；以(上标 99m)Tc-HYNIC-TOCA和(上标 99m)Tc-P829为显像剂，对荷人类小细胞肺癌裸鼠进行显像，通过感兴趣区技术进行半定量分析，计算并比较两种显像剂的靶/非靶比值；在昆明鼠体内进行动态生物学分布实验，测定并比较不同时点两种显像剂在各脏器的克组织百分摄取率。

The finding of cancer halt radiophone in those cancers that hit them module sure support wage targets for take therapies and new imagery agents in the identified communication transduction pathways they ingest and immunotherapy targets by the new proteins and peptides that are created by mutations, translocations, and conjunction anomalies bicentric to the oncogenic advancement in these cancer halt cells.

癌症在各种癌症有他们必将有助于为药物治疗和新确定的信号显像剂的目标他们利用转导通路，并以新颖的蛋白质和多肽免疫指标这也造成了突变，易位和剪接异常中心在这些癌症干细胞致癌进展。

Semiquantitative cerebral blood flow imaging is help of diagnose and treatment of children autism.

99mTcECD显像剂脑血流灌注显像对儿童孤独症的诊断和治疗有一定的帮助。

Autoradiography of aortas demonstrated uptake of the agent into macrophage-rich atheromata identified by Oil Red O staining of lipid deposits.

以油红O染色确定脂质沉积处的动脉粥样硬化瘤，放射自显影技术显示该瘤中富含巨噬细胞并摄取显像剂，荧光镜和流式细胞仪显示主动脉的细胞中主要是巨噬细胞摄取显像剂。

The value of 4,9-diaza-2, 3, 10, 10-tetramethydodecan-2, 11-dione dioxime (HL91) tagged with 99Tcm on detecting the hypoxic brain tissue surrounding the hypertensive cerebral hemorrhage nidus, which represents the penumbra is still waited for confirmation.

采用99Tcm标记的缺氧显像剂4，9-二氮-2，3，10，10-四甲基十二烷-2，11-二酮肟(HL91)检测血肿周围可逆性损伤组织来反映半暗带是否可行，有待证实。

Copper pyruvaldehyde bis（N -methylthiosemicarbazone） complex, or Cu-PTSM, belonging to a class of neutral, lipophilic complexes ,is a positron emission tomography radiopharmaceutical that can be used to evaluate blood flow in the heart, brain, and tumors without following any side effect .

Cu-PTSM是中性亲脂性复合物，用于PET显像的放射性药物由于该制剂很容易扩散到细胞内，因此注射Cu-PTSM后可以了解心、脑和肿瘤部位的血流灌注状况，它不伴有副反应的发生，且合成比较容易，所以是一种非常有途的新型PET显像剂。

copper pyruvaldehyde bis（n -methylthiosemicarbazone） complex, or cu-ptsm, belonging to a class of neutral, lipophilic complexes ,is a positron emission tomography radiopharmaceutical that can be used to evaluate blood flow in the heart, brain, and tumors without following any side effect .cu-ptsm has been demonstrated the ability of rapid diffusion into cells.also because it can be synthesized,it is a potential tracer for pet imaging.

作者单位：610041 四川成都，四川大学华西医院核医学科 cu-ptsm是一种中性亲脂性复合物，用于pet显像的放射性药物。由于该制剂很容易扩散到细胞内，因此注射cu-ptsm后可以了解心、脑和肿瘤部位的血流灌注状况，它不伴有副反应的发生，且合成比较容易，所以是一种非常有前途的新型pet显像剂。

This review discusses the recent development of SERT imaging agents and the research trends for the future.

本文综述了近年来SERT显像剂的最新研究进展，并指出了今后该类显像剂的发展趋势。

These showed that there was an accumulation of agent in strangulated ischemic bowel segment in strangulated loop group and mesenteric venous occlusion group.All results suggest that radionuclide visualization with SPECT could be a valuable method for early diagnosis of acute intestinal strangulation of strangulated loop type and mesenteric venous occlusion type.

本实验结果提示：闭袢型和静脉阻塞型绞窄缺血肠段早期有显像剂的聚集；SPECT的核素显像技术可作为早期诊断闭袢型和肠系膜静脉阻塞型肠梗阻有价值的辅助手段。

Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气，收缩臀部肌肉；拱起身体，尽量抬起头来，右腿伸直朝向天花板（膝微屈，以避免肌肉紧张）。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

粮食产品的运输费用与5月份相比没有变化，但却比去年同期高8％。