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We screened a set of Lewis base organocatalysts derived from chiral pipecolinic acid and tert-butanesulfinamide for the reduction of-N-Cbz-1- phenylpropenamine, including newly designed ones and some of those previously developed in our lab. However, only moderate stereoselectivities, albeit high yields were obtained.

在本课题组前期研究的基础上,我们筛选并设计了一系列以手性哌啶酸和叔丁基亚磺酰胺为母体的有机小分子路易斯碱催化剂,它们能催化三氯氢硅对-N-苄氧羰基-1-苯基丙烯胺的不对称还原,获得很高的收率和中等的对选择性,并且具有很好的底物普适性。

Starting from chiral proline, pipecolinic acid, piperazine-2-carboxylic acid and 1,2-diphenyl amino alcohol, a series of structurally simple and easily prepared amides were developed as highly effective Lewis basic organocatalysts for the asymmetric reduction of imines with trichlorosilane as the reducing agent, which promoted the reduction of N-aryl imines with high yields and excellent enantioselectivities with an unprecedented substrate spectrum.

本文分别由手性脯氨酸、哌啶酸、哌嗪酸以及氨基醇出发,设计和合成了一系列结构新颖、合成简便、性能优良的酰胺类有机小分子路易斯碱催化剂,以廉价的三氯氢硅为氢源,用这些催化剂催化亚胺不对称还原,得到了非常优良的收率、对选择性和前所未有的底物普适性。

Typical metal supports for use in the preparation of printing plates for planographic printing, wherein an image-wise hydrophility-hydrophobity differentiation is produced, are so-called "bimetal" and "trimetal" metal supports, which are built up by superposed metal layers or sheets differing in wettability by water.

典型的金属支持在为平版印刷,其中一个像明智的亲水性,hydrophobity分化制作印版准备利用,这是所谓的&双金属&和&trimetal&金属的支持,这些全部由金属层或重叠了张在不同水润湿。

Prior to electrophoresis, the analytes were purified and preconcentrated by solid phase extraction from plasma.

血清样品通过固相萃取预处理和浓缩,对体的固相萃取回收率在82.9%~90.7%,相对标准偏差RSD%均小于7 %。

The effect of silicon atom in substrate on the reaction rate and the stereoselectivity of enzymatic reactions was revealed by comparison of horse liver alcohol dehydrogenase-catalyzed stereoselective dehydrogenation of the three isomers of acetyltrimethyl propanone and their carbon analogues in aqueous/organic biphasic systems.

本项目通过对比在水-有机溶剂两相系统中,马肝醇脱氢酶催化三甲基硅烷丙酮的三个异构体及其碳类似物的光学选择性脱氢反应,揭示了底物中的硅原子对酶反应速度、立体选择性的影响规律,成功地合成了高对体纯度的手性有机硅醇,并实现了辅酶的再生。

Using THz absorption spectra can distinguish different kinds of amino acids, enantiomers and racemic compounds and structure isomers.

这一研究对建立氨基酸THz谱数据库,及其在氨基酸的手性对体、结构和成分的区别方面有很重要的理论与实践意义。

The purpose of the present work is to find one or two epoxide hydrolase-producing microorganism with high enantioselectivity towards racemic epoxides from the nature and to make researches on the characterization and application of the enzymes.

本研究的目的就是要从自然界中寻找到一到两株能高对选择性地拆分外消旋环氧化物的环氧化物水解酶产生菌,并对酶的性质和应用进行研究。

On the white steps an obscene word, scrawled by some boy with a piece of brick, stood out clearly in the moonlight, and I erased it, drawing my shoe raspingly along the stone.

白色大理石台阶上有哪个男孩用砖头涂了一个脏字眼儿,在月光里分外触目,于是我把它擦了,在五头上把鞋子刮得沙沙作响。

On the white steps an obscene word, scrawled by some boy with a piece of brick, stood out clearly in the moonlight, and I erased it, drawing my shoe raspingly along the stone.

白色大理石台阶上有哪个男孩用砖头涂了一个脏字眼儿,在月光里分外触目,于是我把它擦了,在石头上把鞋子刮得沙沙作响。

All looked colder and darker in that visionary hollow than in reality: and the strange little figure there gazing at me, with a white face and arms specking the gloom, and glittering eyes of fear moving where au rora-can.

在虚幻的像中,一切都显得比现实中更冷落、更阴沉。那个陌生的小家伙瞅着我,白白的脸上和胳膊上都蒙上了斑驳的阴影,在—切都凝滞时,唯有那双明亮恐惧的眼睛在闪动,看上去真像是一个幽灵。

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But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊!不用提了。提到肉,真是糟透了。

Tristan, I have nowhere to send this letter and no reason to believe you wish to receive it.

Tristan ,我不知道把这信寄到哪里,也不知道你是否想收到它。