星形细胞

Objective To investigate the significance of p16 in survival analysis of patients with astrocytoma.

目的探讨p16在星形胶质细胞瘤患者生存分析中的意义。

Purpose:To investigate the expression of Bcl-2 and P16 in brain astrocytoma with their grade of pathological organization.

目的：探讨Bcl-2和P16的表达与脑星形胶质细胞瘤的病理组织学分级的关系。

Objective To study the relationship between GFAP and the malignant degree of astrocytoma.

目的 研究胶原纤维酸性蛋白与星形胶质细胞瘤恶性程度的关系。

The processes of astrocytes in most areas of the brain were thicker and the cell bodies of them were bigger.

而在其他大多数区域包括上面提到的核团中的星形胶质细胞的突起较粗，胞体较大。

These results suggest that astrocytes participate in the functional activity of the central nervous system.

这些结果揭示星形胶质细胞是中枢神经系统功能活动的重要参与者。

RESULTSdiabetic rats showed typical symptoms involving elevated serum glucose and weight loss (2)The rats in DM+VaD group reacted slower and made more error numbers in Y-maze than the rats in VaD group did, with a prolonged total reacting time in a whole day.(3)More neurons with serious damages, such as edema, ischemia or pyknosis could be found in DM+VaD group than in VaD group. More disarrangement of cone neurons, obvious glia proliferation, and more neuron apoptosis were found in CA area of hippocampus. CONCLUSIONS (1)2-VO in STZ-induced diabetic rats succeeded in establishing VaD animal models.(2) The cognitive dysfunction induced by VaD rats had been deteriorated by diabetes mellitus.(3)Morphology evidences proved that diabetes mellitus aggravated brain damages induced by VaD.PART II Effect of diabetes mellitus on the cholinergic nervous systemin CA1 area of hippocampus of VaDOBJECTIVE To estimate the role of cholinergic nervous system in hippocampus during the process of cognitive dysfunction aggravated by diabetes mellitus in DM+VaD group. METHODS Observe the changes of ChAT protein by immunohistochemistry stain. Chose three rats randomly from each group at each pointat two week, four week, and eight week, then sepa

经腹腔注射链脲佐菌素诱导慢性实验性糖尿病，1周后永久性结扎双侧颈总动脉(2-VO)制作VaD模型记录术后2周、4周和8周各组大鼠的体重及血糖；应用Y-迷宫检测空间定向学第二军医大学博士论文中…丈摘…要1ia；一色恤~﹁染澎糕行HE染色观察组织病理学孪叱；胶质细胞原纤维酸性蛋白protellZ，Cf冰尸标记观察星形胶质细舱的激活情况、橄声软公点娜育票票众糯黑橄居端粗默孺篇筑价井袱第二部分糖尿病对血管性痴呆大鼠海马c心区胆碱能神经系统的影响探讨海马CAI区胆碱能神经系统在糖尿病加重确D一大鼠认知障碍中所实验动物及分组同第一部分，应用免疫组织化学染色方法现察海马CAI{介狱牛第晕军l袭拔常博粗{论义

Objective To observe and analyze the expression of fasciculation and elongation protein zeta-1 (FEZ1) gene in purified type-1 astrocytes (T1A) and type-2 astrocytes (T2A).

目的 探讨轴突成束和延伸蛋白ζ-1（FEZ1）基因在1型和2型星形胶质细胞（T1A、T2A）中的表达差异，及其在新生SD大鼠中枢神经系统中的表达。

Under electron microscopic observation, capillaries of SFO are fenestrated ones, the endothelium of them are short of the tight junction, their basement membrane are not intact, the gaps between the endothelium and basement membrane are widened, to which the gaps within the endothelium are opened, the end feet of astrocytes surrond the capillaries not completely, and on the luminal surface of the endothelium some small vesicles are adhere to it, all of which suggesting SFO short of blood brain barrier .

在电镜下观察，穹窿下器的毛细血管为窗性毛细血管，内皮缺乏紧密连接结构，基膜薄而不完整，内皮与基膜之间的间隙宽大，内皮裂隙可通向此间隙，毛细血管内皮腔面可见贴壁小泡，星形胶质细胞脚板未完整包围毛细血管，这些结构特点提示SFO的血脑屏障不完整。

Under electron microscopic observation, capillaries of SFO are fenestrated ones, the endothelium of them are short of the tight junction,their basem ent membrane are not intact, the gaps between the endothelium and basement membrane are widened, to which the gaps within the endothelium are opened, the end feet of astrocytes surrond the capillaries not completely, and on the luminal surface of the endothelium some small vesicles are adhere to it, all of which suggesting SFO short of blood brain barrier.

在电镜下观察，穹窿下器的毛细血管为窗性毛细血管，内皮缺乏紧密连接结构，基膜薄而不完整，内皮与基膜之间的间隙宽大，内皮裂隙可通向此间隙，毛细血管内皮腔面可见贴壁小泡，星形胶质细胞脚板未完整包围毛细血管，这些结构特点提示SFO的血脑屏障不完整。

Antibody of mouse against rat of glial fibrilla acidic protein used to labeling astrocytes of the brain and antibody of rabbit against rat of c-fos labeling c-fos protein in the brain. The second fluorescence antibodies were FITC and Cy3, respectively. Observations of the results and quantitative analysis were conducted with LSCM.

在本实验中，我们应用免疫组织化学的双标方法，用小鼠抗大鼠胶质原纤维酸性蛋白标记大鼠脑内的星形胶质细胞，用兔抗大鼠c-fos标记大鼠脑内的c-fos蛋白，分别应用FITC和Cy3标记的荧光二抗来显示，最后用激光扫描共聚焦显微镜进行观察并定量分析。

We have no common name for a mime of Sophron or Xenarchus and a Socratic Conversation; and we should still be without one even if the imitation in the two instances were in trimeters or elegiacs or some other kind of verse--though it is the way with people to tack on 'poet' to the name of a metre, and talk of elegiac-poets and epic-poets, thinking that they call them poets not by reason of the imitative nature of their work, but indiscriminately by reason of the metre they write in.

索夫农 、森那库斯和苏格拉底式的对话采用的模仿没有一个公共的名称；三音步诗、挽歌体或其他类型的诗的模仿也没有——人们把&诗人&这一名词和格律名称结合到一起，称之为挽歌体诗人或者史诗诗人，他们被称为诗人，似乎只是因为遵守格律写作，而非他们作品的模仿本质。

The relationship between communicative competence and grammar teaching should be that of the ends and the means.

交际能力和语法的关系应该是目标与途径的关系。