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星形细胞

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Objective To study the significance of IL-6 mRNA expression in astrocytomas and its relation with pathological grade in astrocytoma.

目的 研究IL-6mRNA在星形细胞瘤中的表达及其与星形细胞瘤病理分级的关系。

The mean tumor volume at the time of GKS was 2.5 cm3. In 10 cases a tumor specimen was obtained either by open surgery or stereotactic biopsy, securing the diagnosis of pilocytic astrocytoma in five patients and nonpilocytic astrocytoma in five others.

开始GKS治疗时的平均体积是2.5 cm3.10例的肿瘤标本通过开放手术或立体定向的活检获得,得出的诊断是:5例毛细胞性星形细胞瘤,5例为非毛细胞性星形细胞瘤。

The mean tumor olume at the time of GKS was 2.5 cm3. In 10 cases a tumor specimen was obtained either by open surgery or stereotactic biopsy, securing the diagnosis of pilocytic astrocytoma in fie patients and nonpilocytic astrocytoma in fie others.

开始GKS治疗时的平均体积是2.5 cm3.10例的肿瘤标本通过开放手术或立体定向的活检获得,得出的诊断是:5例毛细胞性星形细胞瘤,5例为非毛细胞性星形细胞瘤。

Results Ependymoma and astrocytoma are the most common spinal cord gliomas.The rate of radical resection was higher in ependymoma than in astrocytoma cases.

结果脊髓胶质瘤以室管膜瘤和星形细胞瘤为主,其中以室管膜瘤居多而且手术全切率较高,星形细胞瘤手术全切率较低。

Positive Fas expression was found in astrocytic tumor cells, endothelial cells and gliosis cells.

星形细胞瘤中Fas阳性表达可见于肿瘤细胞、血管内皮细胞及增生的星形细胞

Results 1. The expression of P53, KI-67, hTERT and ToPo II a protein was higher in astrocytoma than that in nomal brain tissue, the expression of these markers was obversely correlated to the grade of astrocytoma (P.05). The expression of Fas was higher in astrocytoma than that in nomal brain tissue, on the contrary, expression of P16 was lower in astrocytoma than that in nomal brain tissue.

结果 1、星形细胞瘤中P53、KI-67、hTERT与ToPoⅡα蛋白表达阳性率高于正常脑组织,P53、KI-67、hTERT与ToPoⅡα蛋白表达与星形细胞瘤的病理组织学分级呈显著正相关(P.05);Fas蛋白在星形细胞瘤中的表达高于正常脑组织,而P16蛋白表达低于正常脑组织,Fas、P16蛋白表达与组织学分级无显著相关性。

The distribution of PA I-1 protein was mainly in tumor cells of high-grade astrocytomas, particularly abundant in areas of vascular proliferation and in tumor cells surrounding necr otic foci, whereas it was only weekly expressed in low-grade astrocytomas.

PAI-1蛋白主要分布在高级别星形细胞瘤的瘤细胞和内皮细胞,尤以血管增殖部位和坏死灶周围较为显著,低级别星形细胞瘤呈低表达。

Stupp R, Mason WP, van den Bent MJ, et al: Concomitant and adjuvant temozolomide and radiotherapy for newly diagnosed glioblastoma multiforme: conclusive results of a randomized phase III trial by the EORTC Brain and RT Groups and YCIC Clinical Trials Group.

星形细胞瘤则为5~10年。毛细胞性星形细胞瘤则为正常寿命。许多脑膜瘤[1]和垂体腺瘤[2]的病人一直没有症状。这些肿瘤被偶然发现,或在死于其它疾病后尸检发现肿瘤。

There was some significant correlation between the measured value of LDH and trypan blue staining.

方法用计算机控制,以不同压力牵张损伤培养于硅胶膜培养皿上的大鼠星形细胞,并于牵张损伤后立即予以1小时低氧应激,用乳酸脱氢酶和台盼蓝定量检测星形细胞在不同条件下和不同时相点的损伤程度。

The results showed that among the parameters clinically used by the pathologists in the diagnoses of astrocytomas,tumor size,giant tumor cell number/high power fieldand mitoses/30HPF were closely related to the DI and PI of the...

结果发现,病理学工作者在星形胶质细胞瘤诊断时所依据的各种参数中,肿瘤体积、每高倍视野瘤巨细胞数和每30个高倍视野中核分裂数与星形细胞瘤DI及PI密切相关,肿瘤平均直径越大、瘤巨细胞数和核分裂数越多,则DI和PI值越高。

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