易兴奋性

Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors. A form of apolipoprotein E, apoE4, contributes to the abnormal accumulation of A and tau, but probably also damages mitochondria and the cellular cytoskeleton. A , tau, apoE and -synuclein interact with many other molecules and modulate diverse signalling cascades that regulate neuronal activity and survival.

最后，易感神经元会萎缩直至死亡，原因可能有兴奋性中毒（神经递质对神经元表面受体的过度刺激引起），钙稳态失衡，炎症反应，能量和生长因子的耗尽。apoE4的产生可导致A肽和tau蛋白的异常聚合，可能也损害线粒体和细胞骨架。A肽、tau蛋白、apoE和突触核蛋白可与很多分子反应，也可调节不同信号级联反应，这些级联反应对于维持神经元活动性和生存性意义重大。

Transgenic expression of IL-1ra and degree of audiogenic seizure of P77PMC rats were observed after infection with pHSV-IL-1ra virus (〓 virus particles) by i. c. v injection and hippocampus injection. Results show: 1. Overexpression of IL-1ra by pHSV-IL-1ra significantly inhibited seizure attacks of P77PMC rat.

实验结果提示IL-1β可导致神经细胞NMDAR mRNA表达及受体活性增加，从而使其兴奋性增高；脑中内源性IL-1系统的异常很可能是形成P77PMC遗传癫痫易感大鼠惊厥易感性的重要因素之一；我们首次构建并鉴定了pHSV-IL-lra重组质粒，并成功地进行了脑内基因转移，使P77PMC大鼠的惊厥程度明显降低。

GABA is resitent to the toxicity of the excitory amino acids because it can promote the conduct of Cl-, prevent the depolarization of the postsynaptic inhibition effectively and the open of Ca2+-gated channel, reduce the metabolic rate of the ischemic nurons.

GABA可以拮抗兴奋性氨基酸的毒性作用，它主要通过促进氯离子的传导，有效的阻断突触后去极化及电压依赖性Ca2+通道的开放，降低正常灌注/缺血性神经元的代谢率和氧的消耗，从而使神经元易耐受缺血性损伤[9]。

The brain of migraine sufferers is therefore able to link an attack with precipitating stimuli such as tobacco, Julio Pascual concludes.

当前认为偏头痛患者存在控制头痛的神经元过度兴奋的状态，偏头痛患者神经元细胞膜上天生有特殊的离子通道，导致渗透性和易兴奋性高，烟草之类的触发因素会让偏头痛患者更易头痛。Julio Pascual总结道

Enhanced wind-up after secondary oesophageal hyperalgesia suggests that isceral pain hypersensitiity induced by central sensitisation results from increased central neuronal excitability.

继发性食管痛觉增敏后的易化效应增强，这表明了内脏痛觉高敏感是由中枢致敏诱发，而中枢致敏由中枢神经的兴奋性决定。

The absorption and distribution of chromium were studied in ryeusing nutrient culture technique and pot experiment.

采用不同浓度K2CrO4(0，0.4，0.8和1.2 mmol/L)的Hoagland营养液处理黑麦幼苗，测定铬在黑麦体内的亚细胞分布、铬化学形态及不同部位的积累。

By analyzing theory foundation of mathematical morphology in the digital image processing, researching morphology arithmetic of the binary Image, discussing two basic forms for the least structure element: dilation and erosion.

通过分析数学形态学在图像中的理论基础，研究二值图像的形态分析算法，探讨最小结构元素的两种基本形态：膨胀和腐蚀；分析了数学形态学复杂算法的基本原理，把数学形态学的部分并行处理理念引入到家实际应用中。