易位的

Objective To study the genetic effect of balanced chromosomal translocation.

目的 研究染色体平衡易位的遗传效应。

Under the γ-rays radiation,the abnormal structure of BM chromosomes mainly showed as chromosome translocation,deficiency and inversion,etc.,among which the translocation was mutual and simple one;and the deficiency was intercalary and apical one.

在电离辐射作用下，野蚕染色体结构异常的表现主要为易位、缺失、倒位等，其中易位的类型为相互易位和简单易位；缺失的类型为中间缺失和顶端缺失。

B. The rook for castling has been moved.

B。参与易位的车被移动过。

In the studies on transferring and identifying alien chro-mosomes into wheat,the combined use of mitotic and meioticchromosome N-banding is also successfully practiced in deter-mination of T.durum-H.villosa amphipoid,five wheatalien disomic additions with H.villosa chromosomes,〓〓,alien sulstitution line with chromosome 〓 andsome translocation lines.

在外源染色体导入、鉴定研究中，利用根尖有丝分裂中期染色体和花粉母细胞减数分裂中期Ⅰ染色体的N-分带，快速、准确地鉴定了硬粒小麦一簇毛麦双二倍体、普通小麦一簇毛麦异耐加系V〓、V〓、V〓、V〓和V〓，普通小麦一簇毛麦异代换系V〓以及一些具有易位的杂种后代。

Majority of acute leukemias in infant, either acute lymphoblastic leukemia or acute myeloblastic leukemia, posses a chromosomal translocation affecting the 11q23 chromosome region which specifically inoles the mixed-lineage leukemia gene.1-3 Most pediatric leukemias with MLL rearrangement clearly hae a remarkably short latency.1,4 MLL gene rearrangement is also associated with secondary leukemias of patients preiously treated with the topoisomerase II inhibitors.4 The latency of these secondary leukemias is similarly ery short.4 Of note, the concordance rate of leukemia with MLL rearrangement in infant monozygotic twins approximates to 100%,1,4 and identical breakpoint in the MLL gene was shared in these pairs of identical twin infants with concordant ALL.1,4 Moreoer, the unique and clonotypic MLL fusion gene was detectable in neonatal blood spots for Guthrie cards from non-twined indiiduals who subsequently deeloped ALL.1,4 These obserations indicate not only that MLL fusion is generated in utero but also that MLL fusion proteins could be capable of inducing leukemic transformation with few, if any, secondary mutations.2,3,4 Greaes et al speculate that an MLL fusion protein somehow promotes rapid transition to full-blown disease in patients ia ery rapid clonal expansion, genetic instability, or inhibition of DNA damage repair.4 In general, for clonal expansion of malignancies, tumor cells often hae acquired strategies that escape immune sureillance of the hosts.5,6 Immune escape mechanisms also contribute to the failure of graft-ersus-leukemia effect after allogeneic hematopoietic stem cell transplantation.7 Therefore, leukemia cells could acquire some immune escape mechanisms during leukemogenesis.

绪论 绝大多数的婴儿白血病，不管是急性淋巴性白血病或是急性骨髓性白血病，在染色体11q23部位有染色体易位的情况；这个部位的染色体易位牵连了混合谱系白血病基因。大多数具有MLL基因重排的儿童白血病潜伏期明显短很多。MLL基因重排也和经拓扑异构酶II抑制剂治疗后的继发性白血病有关。这些继发性白血病的潜伏期类似地都非常的短。很重要的是，单卵双胞胎婴儿同时患有或同时免于MLL基因重排阳性的白血病的一致性接近100%；并且同样患有ALL的同卵双胞胎的MLL基因的断裂点是一致的。而且，这种独特的克隆特异性的MLL融合基因能够从那些得ALL的非双生个体出生时的血斑标本中检测到。这些发现表明MLL融合基因产生在胎儿还在子宫的是后，而且MLL融合蛋白能过和其他的基因突变一起诱导白血病的产生。Greaes 等推测MLL融合蛋白在某种情况下同过快速克隆增殖，遗传的不稳定性或是DNA损伤修复的抑制促使疾病迅速地全面爆发。恶性肿瘤细胞的克隆增殖通常已经获得了逃避机体免疫监视的能力。免疫逃避机制也归因于异体外周血干细胞移植后移植物抗白血病作用的失效。所以，白血病细胞在白血病的产生过程中可能获得了某些免疫逃脱机制。

He also performs a translocation of the wheel to prove there is no hidden axle drive.

他还演奏了易位的车轮证明并无隐轴传动。

Objective:To investigate the effects of Chinese medicine DaHuang et al on bacterial translocation in obstructive jaundice in rats.

目的 ：探讨大黄等中药对梗阻性黄疸大鼠肠道细菌易位的影响。

The transposal material must priority protect and research.

7对与一些具有易位的特殊材料应以重点保护和研究利用。

Use them to attack the uncastled enemy king along the e-file.

用它们去进攻对方位于e-线的未易位的王。

Surprisingly, DEPTOR is highly overexpressed in a subset of multiple myelomas harboring cyclin D1/D3 or c-MAF/MAFB translocations.

令人意外的是，在包含cyclin D1/D3或c-MAF/MAFB易位的多发性骨髓瘤亚群中，DEPTOR高度过表达。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。