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The percentage of TGF-β〓 positive cell in the pancreatic cancer tissue (43.8±5.2)% was significantly higher than that in adjacent pancreatic tissue (28.7±3.6)%, P<0.05. The worse the cancer cells differentiated and lymphy node metastasis, the more over-expression of TGF-β〓. 2. The percentage of Tr positive cell in the pancreatic cancer tissue (41±4)% was significantly higher than that in adjacent pancreatic tissue (23±3)%, P<0.05. The worse the cancer cells differentiated and lymphy node metastasis, the more over-expression of Tr, but the expression of Tr protein was not correlated with lymphy node metastasis (P>0.05). 3. The percentage of β-GCD positive cell in the pancreatic cancer tissue (62.5± 4.1)% was significantly higher than that in adjacent pancreatic tissue (33.5±2.8)%, P<0.05. The worse the cancer cells differentiated and lymphy node metastasis, the more over-expression of β-GCD in pancreatic cancer tissue, but the expression of β-GCD protein was not correlated with lymphy node metastasis. P>0.05. 4. the expression of β-GCD was significantly correlated with TGF-β〓 and Tr in the pancreatic cancer tissue.

结果如下:1、胰腺癌组织TGF-β〓阳性细胞百分率(43.8±5.2)%明显高于癌旁胰腺组织(28.7±3.6)%,P<0.05;且癌细胞分化愈差或有淋巴结转移TGF-β〓过度表达愈多。2、胰腺癌组织Tr阳性细胞百分率(41±4)%,明显高于癌旁胰腺组织(23±3)%,P<0.05;且不同分化程度胰腺癌组织Tr表达强度不同,分化程度愈低,表达强度愈高,P<0.05;但胰腺癌Tr表达强度与淋巴结是否转移无关,P>0.05.3、对于胰腺癌组织TGF-β〓和Tr表达,检测胰腺癌组织(32例)β-GCD阳性细胞百分率分别为(62.5±4.1)%或(62±4)%,分别明显高于癌旁胰腺组织β-GCD阳性细胞百分率(33.5±2.8)%或(43±3)%,P<0.05;不同分化程度胰腺癌组织β-GCD表达强度不同,分化程度越低,表达强度越高,P<0.05;但胰腺癌组织β-GCD表达强度与淋巴结是否转移无关,P>0.05.4、TGF-β〓、Tr和β-GCD在胰腺癌组织中的表达随着分化程度的改变,呈现一致性的关系,而且TGF-β〓与淋巴结转移有关,Tr和β-GCD与淋巴结是否转移无关。

Results Contrast CT or MRI showed prominent irregular circular or nodular enhancement in 14 of 16 cases (64%),can not distinguished from postopertative changes, radioinjury, tumor residue or recurrence.Among them, 9 cases showed tumor residue or recurrence based on significantly increased FDG uptake, 5 were confirmed by pathologic study. The other 5 cases of cerebral necrosis and 2 cases with postoperative cerebral malacia demonstrated FDG uptake defects.

结果 16例中87.5%(14例)CT和MRI表现不规则环形或结节状明显强化,不能准确作出手术后改变和放射治疗后脑损伤、残存肿瘤或肿瘤复发的诊断;其中9例残存肿瘤或肿瘤复发病灶18F-FDG PET影像表现为葡萄糖代谢明显增高,有5例得到手术病理证实;另5例术后放射治疗后脑损伤患者和2例术后软化灶18F-FDG PET影像均显示局部病变区为放射性分布缺损或明显低下。

The flexor hallucis longus was about (3.24±2.32) mm lateral to the center of metatarsophalangeal joint. Dorsal skin of big toe was innervated by saphenous nerve, superficial and deep fibular nerve.

(1)正常与外翻足的比较中,伸肌腱的位置在足横纹及止点处无明显的差异,在跖附关节及跖趾关节处,外翻足的伸肌腱明显外移(P.05):长屈肌腱也明显外移(P.05)。

Morphometrical analysis of irradiated arteries exhibited the decreased percent area stenosis compared with the control both in 14Gy and 28Gy radiation group. This effect was not observed in 7Gy group and the adverse effect was seen in 3. 5Gy group.

形态学分析显示与对照组相比,14Gy剂量组和28Gy剂量组的狭窄面积百分数明显减小,7Gy剂量组不明显,而3.5Gy剂量组狭窄面积百分数明显增加。56Gy剂量放射治疗后出现副作用。

Compared with the control group, the number of TRAP(superscript +) multinuclear cells, TRAP activity and the percentage of bone surface in lutein middle-dose group and lutein high-dose group significantly decreased (P.05). But the expression of RANK mRNA significantly increased (P.05) by treated in different doses of lutein.

诱导培养的破骨细胞形态特征明显;叶黄素中、高剂量组在细胞数量、TRAP活性上与对照组相比有明显统计学差异(P.05);叶黄素各剂量组在mRNA表达量上与对照组相比有明显统计学差异(P.05),且呈量效关系。

Compared with the control group, the number of TRAP+ multinuclear cells and TRAP activity of trans-resveratrol middle-dose group and trans-resveratrol high-dose group have significantly decreased (P.05). But the expression of RANK mRNA has significantly increased (P.05) being treated in different dose trans-resveratrol.

结果 诱导培养的破骨细胞形态特征明显;反式白藜芦醇中、高剂量组在细胞数量、TRAP活性上与对照组相比有明显统计学差异(P.05);反式白藜芦醇各剂量组在mRNA表达量上与对照组相比有明显统计学差异(P.05),且呈量效关系。

The four methods all can improve limbs function, activaties daily life, myodynamia, but no significant difference among four methods.

而针刺痉挛侧穴位强、弱刺激治疗前后临床痉挛指数、Ashworth评分未见明显改善,强、弱刺激之间也未见明显差别。4种不同方法对痉挛性偏瘫的肢体活动能力、日常生活能力、肌力均能起到改善作用,但是4种方法之间肢体活动能力、日常生活能力、肌力比较未见明显差别。

GA had no effect on SMA constriction induced by NE. The reactivity of SMA rings to myricetin was increased at 0, 0.5, 1 hour and 2 hours after shock, and it reached the peak at 2 hours, then it significantly decreased at 3 hours and 4 hours after shock.

结果 SMA血管环对NE的反应性表现为:休克0 h和0.5 h组明显高于正常对照组和其他休克时间点组,休克1 h和2 h组明显低于正常对照组和休克0 h和0.5 h组;18α-GA对NE诱导的SMA血管环收缩反应性无明显影响。

The experimental data demonstrated that there was a nasalward directional preference in oath OKN system under both close loop and open loop conditions, and the nasalward OKN gain evoked by stimulation of nasal retina was much higher than that at temporal retina. ms indicates that OKN nasalward preference is mairily derived from the nasal retina, i. e. the direct path1Vay of OKN dominates the indirect pathway in cat's OKN system. The gains of temporalward and nasalward OKN from temporal retina are much less than those of nasalward OKN from nasal retina. It is suggested that the indirect pathway of OKN in the cat only possesses a supplementary function, Which probably plays an important role in temporalward OKN eye-movments in relation to binocular vision.

实验结果显示:高速度刺激的闭环OKN反应及开环OKN反应均对鼻向运动刺激有明显的方向选择性;半侧视网膜刺激时,鼻侧半视网膜的鼻向OKN增益明显高于颞侧半视网膜的鼻向增益,说明猫的OKN眼动反应以跟踪鼻向运动为主,并且这种对鼻向运动刺激的选择性主要来源于鼻侧半视网膜,亦即来源于OKN直接通路;颞侧半视网膜的鼻、颞向眼动增益均明显低于鼻侧半视网膜的鼻向眼动增益,说明猫的OKN系统的间接通路在OKN眼动控制中起辅助作用,并可能主要对颞向OKN眼动起作用从而与双眼视觉功能相关。

Simultaneously 15 samples of normal nephric tissue were used as control.The sections from these samples were subjected to immunohistochemical analysis with antibodies directly against uPA and PAI-1 by LSAB method. In this study we adopt semiquantitative analysis to determined the expression of these molecules , and utilized the relevant data processing and statistical analysis to evaluate the correlation between their expression and the clinicopathological features of RCC.Results: 1. The positive rate of uPA and PAI-1 of uPA in RCC were 72%(36/50)and 56%(28/50), respectively.But in control group there was nearly

正常肾组织标本中几乎无阳性染色。2、uPA表达水平与患者年龄、性别、肿瘤病理分级无关(均P>0.05),与T分期、淋巴结转移有明显的相关性(r=0.684,P<0.05;r=0.789,P<0.05),uPA高表达多见于T_(3-4)、有转移的RCC.3、PAI-1的表达水平与患者年龄、性别、肿瘤病理分级和T分期无关(P>0.05),与淋巴结转移有明显的相关性(r=0.800,P<0.05),PAI-1高表达多见有转移的RCC.4、对uPA和PAI-1行相关性检验,uPA在RCC中的表达与PAI-1的表达呈明显正相关(r=0.168,P<0.05)。5、uPA和PAI-1的表达与淋巴结转移的关系以Logistic回归法进行分析,结果显示uPA与区域淋巴结转移密切相关,uPA是淋巴转移的危险因子(RR=2.718,95%CI=1.150~7.170,P=0.024),PAI-1则不是淋巴转移的危险因子(RR=1.599,95%CI=0.624~4.102,P=0.328)。

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