明显

3NE、MTT、LDH、ET-1、ICAM-1 and Tie-2experiment show: in the process of oxygen glucose deprivation/reoxygenation ,BMEC have subjected great damagement, I/R groups have significant differences compared with NC groups (p.05);polymorphonuclear leukocyte can aggregrate this injury, I/R+PMN groups have significant differences compared with I/R groups (p.05); after Sivelestat Sodium treatment, the effect of I/R injury has been decreased, I/R+PMN+Siv groups have significant differences compared with I/R+PMN groups (p.05), and NE、MTT、LDH experiment show that the three dose groups there was a significant dose-effect relationship.

3测定NE、MTT、LDH、ET-1、ICAM-1、Tie-2 mRNA均显示：氧糖剥夺/复氧复糖过程能对BMEC造成损伤，I/R组与NC组比较有明显的统计学差异(p.05)；中性粒细胞能加重对BMEC的损伤，I/R组与I/R+PMN组之间比较亦有统计学差异(p.05)；西维来司钠处理后，血管内皮细胞的损伤明显减轻，I/R+PMN组与I/R+PMN+SIR组比较有统计学差异(p.05)，并且NE测定以及MTT、LDH实验提示在西维来司钠三个剂量组之间存在明显的量-效关系，其对BMEC的保护作用有剂量依赖性。

After this research work, we know that: HMCM-22 is a better catalyst of selecting naphthalene alkylation; Surface modification of zeolite Y is effective, but the effect of zeolite 3 is not evident and surface modification doesn"t suits mordenite; Surface modification doesn"t affect the frameworks and inner environments of zeolites, but only reduces diameter of orifice and overlays surface acidities; t-butanol is not suitable for alkylating agent of the reaction using modified zeolites as catalyst; Solvents with smaller molecular size are advantageous for naphthalene alkylation reaction using modified zeolites as catalyst, such as cyclohexane is better than decalin.

通过本论文的研究，我们知道：HMCM-22是萘择形烷基化反应较好的沸石之一；Y沸石的外表面改性效果较好，β沸石则效果不明显，而丝光沸石则不适于外表面改性；外表面改性不改变沸石的骨架结构和孔道内部环境，仅减小孔口直径和覆盖外表面酸性位；叔丁醇不适于作外表面改性沸石催化的反应的烷基化试剂，其反应活性很低，且选择性无明显提升；分子较小的溶剂更适于外表面改性沸石催化的反应，环己烷就明显好于十氢萘。

Double positive rate was about 80%. Albumin increasingly expressed following induction, but alpha-fetoprotein decreasingly expressed. Simultaneously, c-kit mRNA levels were significantly reduced. No significant changes were found in keratin-19 levels.

细胞诱导后肝细胞标志物白蛋白表达明显增加，而作为不成熟肝细胞的经典标志物甲胎蛋白表达减少，同时干细胞标志物 c-kit mRNA水平也明显下降，角蛋白19水平无明显变化。

However, there were a great number of inflammatory cells, epithelial proliferation, partial breakage and defluvium of the airway epithelium in the bronchus, below the vessel mucous membrane and around lung tissues in the model control group.

正常对照组小鼠气道无明显炎症改变；模型对照组小鼠支气管、血管粘膜下和周围肺组织有明显炎症细胞浸润、气道上皮增生、气道黏液增多、气道上皮部分断裂脱落；细胞移植组小鼠气道炎症明显减轻。

Result］the total operative effective rate of double-tube diastematomyelia amounted to 86% during a follow-up period of 6 months to 15 years,more significant in patients with pain.the scores of neural function and ptncsep were significantly improved.

结果］双管型脊髓纵裂通过手术后观察和6个月～15年(平均2年6个月)的随访发现，临床神经功能评分及 ptncsep术后有明显改变，尤其是疼痛为主诉的患者恢复最为明显，手术的总有效率可达86%；单管型脊髓纵裂手术前后无明显变化。

Result］The total operative effective rate of double-tube diastematomyelia amounted to 86% during a follow-up period of 6 months to 15 years,more significant in patients with pain.The scores of neural function and PTNCSEP were significantly improved. But patients with single-tube diastematomyelia had no obvious change after operation.

结果］双管型脊髓纵裂通过手术后观察和6个月～15年(平均2年6个月)的随访发现，临床神经功能评分及 PTNCSEP术后有明显改变，尤其是疼痛为主诉的患者恢复最为明显，手术的总有效率可达86%；单管型脊髓纵裂手术前后无明显变化。

Eighthly, evolution of economic structure contributes little to economic growth of Shaanxi Province, regional economy in Shaanxi Province develops offbalance, the county-level economy takes on backwardness and urbanization rate is inferior to national average level and average world standard and lags behind obviously industrialization.

第八，经济社会结构演化对陕西省经济增长的贡献率低但较稳定，陕西省区域经济发展不平衡，县域经济落后，城镇化率低于全国平均水平和世界平均标准，并明显滞后于工业化水平；公有经济比重明显高于民营经济，民营经济比重明显低于全国平均水平；开发区作用日益增大。

However, electropuncture group had obviously better curative effect than filiform needle group and there was very significant difference between the two groups in total effective rate. The time used to relieve symptoms in electropuncture was shorter than filiform needle group.

但在同样取穴和疗程情况下，则电针组的疗程明显优于单纯毫针组，其总有效率比较有显著性差异；且症状减轻所需时间亦明显较单纯毫针组短；在病例的治愈率方面亦明显优于单纯毫针组，其治愈率比较有非常显著性差异。

These findings were consistent with the results of E20 cerebral cortex. iNOS was detected in E14 brain and There were no evidence changes of expression of iNOS in the encephalocoele group compared with the control group.

在Western blot分析中，发现与对照组比较，E14脑膨出组胎鼠大脑皮质中nNOS蛋白表达明显减少，eNOS蛋白表达水平明显增加，与E20结果相一致；在E14胎鼠大脑皮质中检测到iNOS蛋白微量表达，但脑膨出组与对照组比较无明显差异，E20胎鼠大脑皮质中未检测到iNOS表达。

Expression of Caspase-3 and bcl-2 protein In E20 cerebral cortex, the expression of cleaved Caspase-3 in the encephalocoele group are higher than that in control group, and the expression of bcl-2 in the encephalocoele group are lower than that in control group. These findings were consistent with the results of the western blot analysis in E14 Brain.

四、Western-blot检测E14、E20胎鼠大脑皮质中caspase-3、bcl-2蛋白的表达 1、用Western-blot方法检测不同组E20胎鼠大脑皮质中caspase-3、bcl-2蛋白表达水平，结果表明对照组、给药无畸形组、脊柱裂组胎鼠大脑皮质中caspase-3、bcl-2蛋白表达水平无明显改变，而脑膨出组胎鼠大脑皮质中caspase-3蛋白活化片段表达水平明显增加，bcl-2蛋白表达水平明显减少。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐