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As noted above,membrane-stabilizers unexpectedly improved the heart function andprevented ER stress both in vivo and in cultured cells.We know that the membranestability depends on the sodium homeostasis in fact.To investigate whether ER stress isassociated with sodium channel action,which determins the membrane stability,wepretreated H9c2(2-1) cells with veratridine,a sodium channel activator.

上面的研究发现膜稳定剂在体内体外均抑制了内质网应激,并改善了心脏功能,而膜稳定作用实际上是维持细胞钠离子稳态的结果,为了研究内质网应激反应与钠离子活动的关系,我们用一种钠通道激活剂藜芦定刺激H9c2(2-1)细胞,30分钟时GRP78表达增加;24小时时PERK磷酸化和CHOP蛋白表达显著增加,说明钠离子通道过度激活诱发了内质网应激反应。

In today's world of images, attentive vigilance is required, since this temptation is great.

在今天这个重视形象的世界,需要时时警觉,因为这样的诱惑是相当大的。

It is happy to talk love with a smart person because he is humorous and voluble.

和聪明的人恋爱很快乐,因为他们很幽默,会说话,但也时时存在着危机,因为这样的人容易变心,和老实的人恋爱会很放心,但生活却也非常乏味。

In a tree there warble two white pigeons.A solitary dove changes its place now and then,and utters a monotonous noise.

两只白鸽在一棵树上鼓噪;另一只孤单的白鸽时时转换地方和发出单调的声音。

Whisk her off to your favorite restaurant, stare lovingly into her eyes, touch her hand or leg frequently while casually talking throughout the meal.

约会 带她奔向你最爱的餐厅,含情脉脉地直视她的双眸,在就餐过程中谈谈心,时时爱抚她的双手与双腿。

Ah, Wilhelm, to what does not my heart often compel me!

威廉啊,我的心时时渴望到她身边去!

May the sun always shine in your windowpane.

愿阳光时时照在您的玻璃窗上。

We must always keep ourselves within the bounds of discipline.

我们要时时用纪律约束自己。

We come back to live in the wonderfulness present; to plant our heart's garden with good seeds; and to make strong foundations of understanding and love.

请让我们回到美好的当下,时时将善的种子植入心田,以创造爱和了解的稳固的基石。

And the wristband definitely becomes a reminder for everyone of us that we should work hard, chase our dreams and help people around us.

同时,这个手环也时时提醒我们我们应当努力追逐梦想,同时要帮助周围人。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。