时基

Results We can induce MSCs into osteoblasts which can express gene col Ⅰ and ALP. Through analysis growth curve, we demostrateed the diphosphonate or assemble flavone of drynaria rhizome with 10^(-4)~10^(-6)mmolL^(-1) had the inhibition on the osteomast; it with 10^(-8)mmolL^(-1) had a promotion on the osteoblast; it with 10^(-10)~10^(-12)mmolL^(-1) had a restraint on osteoblast. Conclusion Through gene analysis, we found the diphosphonate or assemble flavone of drynaria rhizome can have the promotion on the osteoblast.

结果 骨髓基质细胞经过4周诱导可转化为表达colⅠ和ALP的成骨细胞，经过生长曲线分析，二磷酸盐和骨碎补总黄酮10^(-4)~10^(-6)mmolL^(-1)时，对诱导后的成骨细胞有抑制作用；10^(-8)molL^(-1)有促进作用；10^(-10)~10^(-12)mmolL^(-1)不明显，其中10^(-8)mmolL^(-1)作用最强；基因分析后，发现二磷酸盐和骨碎补总黄酮促进成骨细胞表达colⅠ和ALP，且两者合用效果大于单独用药。

The results showed that, the accuracy of emotional recognition and preference for emotional judgment did not differ between the dysphoric and nondysphoric individuals. However, the dysphoric individuals tended to respond to non-positive facial emotions with negative cognitive-conceptual and affective schemas.

而在同等脸部情绪之辨识与判断表现的基准上，忧郁倾向个体在面对负向、甚至所有非正向之脸部情绪讯息时，明显展现认知概念与情绪向度上的负向认知基模反应倾向。

Cm^2 of nitromethane electroreduction appeared at -0.89 V and the reaction activation energy was 12.3 kJ/mol.

SCE时，硝基甲烷还原为甲基羟胺的电流达14.9mA/平方公分，其反应表观活化能为12.3kJ/mol。

Specifically, itcontains 8 chapters.In chapter 1, the formation, structures, properties and the futureprospect of liposome were thoroughly reviewed;In chapter 2, the stibility and permeability of phopholipid -eleostericacid liposome were studied together with the effect of polymerizationof eleostearic acid. This membrane system was very sensitive to 〓,the effect of 〓 was clarified to increase the aggregation/fusion ofliposomes and made the permeability of mixed liposomes much higher;In chapter 3, two polymerizable conjugated diyne bolaamphiphiles were synthesized. They could form very stable mixed liposome, andthe diyne could be polymerized by UV light in bilayer liposomes, as aresult, the stability of mixed liposome against solvent or surfactantafter polymerization were enhanced. In chapter 4, two kinds of amphiphilic amino acids were synthesized andstable liposomes were formed therefrom After the condensationpolymerization of amino acid in bilayer liposomes, stable polypeptide liposomes were obtained, which had lower phase transition temperatureand higher permeability.In chapter 5, four kinds of glycolipids were synthesized and theiraggregation behavior in water was comparied. When incorporated intophospholipid bilayer membranes, they could increase the phase transitiontemperatures and inhibit the aggregation and fusion of mixedliposomesat lower temperature.In chapter 6 and 7, three kinds of steroidal bolaamphiphiles withdifferent chain lengths were synthesized. Incorporation of steroidalmoiety to the center of lipid bilayer membrane obviously increased themobility of lipid membrane and shifted Tc to lower temperature side incomparasion with cholesterol. The bolaamphiphile which was shorter thanthe hosted lipid bilayer membrane thickness influenced the lipid packingmore obviously.

全文共分8章：第一章对脂质体的形成、结构、性质及展望进行了较为详细的文献综述；第二章研究了磷脂-桐酸脂质体的稳定性，通透能力及桐酸的聚合对这些性质的影响；磷脂-桐酸混合脂质体为一类对〓灵敏的脂质体，〓的作用首先是使脂质体集聚然后使脂质体融合，并加速内包荧光物的释放；第三章通过合成两种可聚合共轭双炔双极性双亲分子DDCA，DDOL，研究了共双炔分子在双分子层脂质体膜上的聚合及对脂质体性质的影响，聚合可以提高脂质体相对于溶剂及表面活性剂的稳定性；第四章合成了两类氨基酸为极性基团的双亲分子，它们均可以在超声下形成稳定的脂质体结构；氨基酸基团可以在脂质体上进行缩聚反应，若聚合后脂质体表面仍有足够的亲水能力，则可得到稳定的多肽型脂质体；聚合后脂质体的相变温度降低，通透能力增加；第五章合成了四种亲水基团为单糖基的双亲分子GL-l，GL-2，GL-3， GL-4，研究了它们在水中的分散情况、集合体形态与分子结构的关系；在DMPC双分子层膜中加入糖脂分子可以使脂质体的相变温度提高，阻止脂质体在低温放置时的集聚与融合；第六章-第七章合成了三种不同碳链长度的双极性含胆甾环双亲分子 CL-1，CL-2，CL-3；它们可以象胆固醇一样与磷脂混合形成稳定脂质体，胆甾环基团位于脂质体双分子层膜的中间；与胆固醇的作用相反，它们可以增加磷脂双分子层膜的流动性，降低混合脂质体的相变温度；三种分子的作用与其碳链长度和磷脂双分子层膜的厚度有关，比膜厚度短的分子影响最大。

Three components of peroxide in the activator amongwhich have the different decomposed temperatures made the Vinyl-ester resinsolidified heat discharge increased that gained a bigger solidified degree. Theactivator-adopted quantity can dramatically affect the casting samples performance:eg. When use 1.0-1.4 portions of activator, the casing sample can reach its maximumTensile strength and Bend strength; when use more activator, the polymeric meshworkcontracted which embrittle the casing sample and reduce the dynamic performance; Inthe Pultrusion processing, when CF composed of about 60vo1%, more demould agentcan bring the better processing but degrade the CFRP, normally use around 1.2 portion.

采用具有不同分解温度的三组分有机过氧化物引发剂，乙烯基酯树脂的固化反应放热量增加，固化程度提高；引发剂用量对浇注体的性能影响很大，在用量为 1.0~1.4 份时，浇注体拉伸强度剂弯曲强度达到最高，过多的引发剂使聚合网络减小，浇注体变脆，力学性能降低；在拉挤成型工艺中，碳纤维的体积含量一般为 60%左右，脱模剂增加使加工性能好转但会使复合材料性能下降，一般用量为 1.2 份。

A clear cause-and-effect relationship between excessive myocardial MMP-1 activity, increased mysial collagen degradation, and progression to systolic HF has been shown experimentally through the use of transgenic models and the use of pharmacological MMP activators.53,54 In addition, experimental evidence has been provided showing that following chronic neurohormonal activation, increased synthesis and release of MMPs into the local extracellular matrix of the cardiomyocyte occurs,55 which in turn could contribute to endomysial and perimysial collagen degradation and disruption.

一个明显的因果过多的心肌MMP-1关系活动， mysial增加胶原蛋白的降解和进展收缩性心力衰竭已被证明试验，通过使用转基因模型和使用的MMP药理作用此外，activators.53，54实验证据下面被提供显示慢性神经激活时，增加的MMPs合成和释放到当地的细胞外基质的心肌细胞发生，55反过来有助于人肌内膜和 perimysial胶原退化和破坏。

Subsequently,enol methylation of P in basic condition completed the synthesis of malyngamide O.Applied this route to the synthesis of malyngamides Q and R,the chiral unsaturated acid was connected with the vinyl chloride part by amidation,then the resulting product was converted into the corresponding aldehyde,followed by aldol condensation of the aldehyde with the chlorotitanium enolate of pyrrolidone to complete the skeleton of malyngamides Q and R,then the synthesis of them was completed via enol methylation in acid condition.

该合成路线拓展应用到malyngamides Q和R的合成时，首先用酰胺键将手性不饱和脂肪酸和烯氯片段连接，再转化成相应的醛，与乙酰基吡咯酮进行TiCl_4催化的aldol反应即得到malyngamides Q和R的骨架结构，再经过酸催化的烯醇甲基化反应完成了Q和R的全合成。

The 23-year-old WAG showed off her toned figure and enviably flat stomach in a black bikini while on holiday with son Kai in Barbados.

这位23岁的新妈咪在和儿子Kai在巴巴多斯岛度假时，身着黑色比基尼，大秀自己健康的肤色和平坦的小腹。

When methoxyethanol was used as the solvent,tantalum ethoxide can be chemically modified with acetic acid to producetantalum alkxo-acylate precursor, and therefore the hydrolysis of 〓can be slowed down.

在以乙二醇单甲醚为溶剂时，乙醇钽与醋酸作用生成乙醇钽的乙酰基配位化合物，可以减弱水解反应的进行。

Leaves fasciculate, basally gradually narrowed into a long petiole; leaf blade narrowly oblong-lanceolate to lanceolate, 45--55 × 2--5 cm, glabrous, turning blackish when dry.

束状的叶，基部逐渐狭窄成长叶柄；叶片披针形狭长圆形的到披针形， 45-55 * 2-5 厘米，无毛，干燥时变微黑。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。