早幼粒细胞

Objective:To observe the therapeutic efficacy and side effect of all-trans retinoic acid combined with arsenic trioxide(As2O3)on newly-diagnosed patients with acute promyelocytic leukemia.

目的：观察全反式维甲酸联合三氧化二砷(As2O3)治疗初发急性早幼粒细胞白血病的疗效和不良反应。

AbstractObjectiveTo observe the therapeutic efficacy of all-trans retinoic acid combined with arsenic trioxide(As2O3) on acute promyelocytic leukemia.

中文摘要：摘要目的研究全反式维A酸联合三氧化二砷治疗急性早幼粒细胞性白血病可产生的协同作用。

Acute promyelocytic leukemia ; All-transrefinoic acid ; Arsenic

急性早幼粒细胞白血病；全反式维甲酸；砷剂

ABSTRACT］ Objective To observe the efficacy and side effects of combined therapy with alltrans retinoic acid, arsenic trioxide (As2O3) and chemotherapeutics for newly diagnosed acute promyelocytic leukemia.

急性早幼粒细胞白血病是急性髓系白血病中的一种独特类型(M3型)，以特异的染色体易位t(15，17)(q22，q21)为特征，形成PMLRARa融合基因，该融合基因是APL发病的分子基础和分子标志。

Objective To investigate the effect of oleanolic acid on the expression of bcl-2 and bax gene in HL60 cells.

目的 探讨齐墩果酸对人急性早幼粒细胞白血病HL60细胞bcl-2和bax基因表达的影响。

Objective To investigate the effect of butyric acid and its derivative tributyrin in combination with all-trans retinoic acid on differentiation induction of APL cells.

目的 研究丁酸类衍生物联合维甲酸对急性早幼粒细胞白血病患者原代培养细胞的诱导分化作用。

December 2005 by the Chinese Ministry of Health Group compilatory the "Modern Chinese medical papers election" was officially published ,"quick-impact cooling of Hope fast rule acute leukemia" published in the 508 p .

2005年12月由中国卫生部组编纂的"中国现代医学论文选"正式出版，"速效冷却的希望快统治急性早幼粒细胞白血病"，刊登在508页。

June 5, 2007 by the China Association physicians group compilatory the "modern medical technology and clinical application papers election" was officially published,"Quick-impact Tui Re Ling cured the acute leukemia quickly" published in the 139 p .

2007年6月5日，由中国医师协会编纂组的"现代医疗技术和临床应用论文选"正式出版，"速效，吊重玲治愈了急性早幼粒细胞白血病迅速"刊登在139页。

Methods 39 patients with APL were analyzed by cytogenetics and were performed by karyotype analysis with Rbanding techniques.

目的 探讨细胞遗传学在急性早幼粒细胞白血病的诊断及预后评估中的应用价值。

Objective To investigate the changes of reticulated platelets levels in patients with acute promyelocytic leukemia,and to provide some useful information about the recovery of hematogenesis for patients with APL during clinical treatment and whether platelets infusion is necessary.

目的 了解急性早幼粒细胞白血病患者外周血网织血小板水平的变化规律，为APL临床诊治过程中骨髓造血功能的恢复及掌握血小板输注时机与频率提供理论依据。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。