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Photofragment translational spectroscopy is an ideal tool to investigate photodissociation dynamics under collision-free conditions through which one can obtain the total center of mass translational distribution, angular distribution, and the branching ratios for different possible product channels by measuring the angle-resolved time of flight spectra of photofragments. Information about photodissociation processes such as dissociative lifetime of parent molecule, the orientation of transition dipole moment, and the symmetry change of the highly excited states can be deduced from the translational energy distribution and angular distribution.

碎片平动能谱方法是在无碰撞条件下研究光解动力学的一种理想方法,它通过测量光致碎片在不同角度的时间飞渡谱(Time of Flight,简称TOF),可以得到光解碎片质心系的平动能分布、角分布和不同解离通道之间的分支比等,由此可以推知母分子的解离寿命、跃迁偶极距的取向以及激发态分子的对称性变化等过渡态的动力学信息。

Light holds between its hands The white hill and black oaks, The path that goes o, The tree that stays; Light is a stone that breathes By the sleepwalking river, Light: a girl stretching, A dark bundle dawning; Light shapes the breeze in the curtains, Makes a living body from each hour, Enters the room and slips out, Barefoot, on the edge of a knife; Light is born a woman in a mirror, Naked under diaphanous leaves, Chained by a look, Dissolved in a wink; It touches the fruit and the unbodied, It is a pitcher from which the eye drinks clarities, A flame cut in blossom, a candle watching Where the blackwinged butterfly burns; Light opens the folds of the sheets And the creases of puberty, Glows in the fireplace, its flame becomes shadows That climb the walls, yearning ivy; Light does not absolve or condemn, Is neither just or unjust, Light with impalpable hands raises The buildings of symmetry; Light escapes through a passage of mirrors And returns to light: Is a hand that invents itself, An eye that sees itself in its own inventions.

光 双手拥着白色山峦与黑色橡树林,前行的路,停留的树;光是梦游的河旁呼吸的石光:一个女孩舒展,一束暗色破晓。光勾勒出帘中微风的形状,每时每刻造出一个鲜活的身体,光著脚,踩著刀刃;蹑入房间,又溜走;光是镜中诞生的女人,裸露在透明的叶底,被目光锁定,瞬间消逝;它触摸著果实和无形,眼睛在它的水罐饮著清晰,火焰绽放如花,蜡烛目睹黑翅的蝴蝶燃烧光展开被单的折皱与青春期的皱痕在壁炉里光芒焕发,它的火焰成影在墙上攀爬,怀恋著长春藤光既不赦免也不谴责无公平与不公平而言光,用无法察觉的双手举起对称的建筑;光在镜子的通道里逃遁返回于光:一只发明自己的手,一只在自己的发明中看到自己的眼。

Recently, many foreign researchers found that the tetrodotoxin-resistant voltage-gated sodium channel, Nav1.8, which is expressed only by unmyelinated small-diameter sensory neurons associated with nociception in dorsal root ganglion and trigeminal ganglion, is involved in pain pathways and play a key role. Thus it provides a new idea in pain research.

近年来,国外众多学者发现河豚毒素(tetrodotoxin,TTX)不敏感型(TTX-resistant,TTX-R)电压门控钠通道Na_v1.8与疼痛的关系极为密切,其仅分布在背根神经节(dorsal root ganglion,DRG)和三叉神经节(trigeminal ganglion,TG)中的与伤害性感受密切相关的无髓鞘的小直径感觉神经元胞体上,它为疼痛的研究提供了新的思路。

Adopting the system and method in the invention tessellates to exchange the data according to bit and realizes the function of executing non-blocking exchange according to the bit in time slot; the invention is able to output any input bit on the appointed position of all needed outputting channel, which not only improves the flexibility of the data exchange, but also decreases the cost and has high cost performance.

采用本发明的系统及方法,细化到将数据按照比特进行交换,并且实现了按照时隙中的比特进行无阻塞交换的功能,可以让任意一个输入的比特在所有需要输出通道上的指定位置输出;不仅提高了数据交换的灵活性,而且降低了成本,性价比高。

The results showed that (1) all the arteries tested had tachyphylaxis to peptidergic agonists;(2) the desensitization of the arteries tested to catecholamines was uneasy except BA;(3) the desensitizations to AⅡ, AVP and PE were homologous;(4) the endothelium-EDRF -cGMP pathway had no contribution to the tachyphylaxis of PA to AⅡ and AVP;(5) membrane receptor cycling (internaliation and re-insertion) contributed only in part to homologous desensitization;(6) there was no change in the function of voltage-dependent Ca〓 channel during desensitization to AⅡ and AVP;(7) some changes in G protein occurred during homologous desensitization;(8) the most surprising finding was that the caudal arterial smooth muscle of stroke-prone spontaneously hypertensive rat showed tachyphylaxis to α〓-adrenoceptor agonist PE, while the tachyphylaxis of pulmonary artery of SHR was not changed compared with that of Wistar rat.

脱敏是消除效应的一种有效方式。因此,研究不同血管对不同激动剂脱敏的差异及阐明脱敏的机制,有助于阐明血管活动个性化的机制。研究表明:血管对肽类激动剂的脱敏方式为快速脱敏,而对儿茶酚胺类激动剂不易脱敏;血管对肽类激动剂和儿茶酚胺类激动剂表现为同源脱敏;内皮-NO-cGMP通路不参与肺动脉对AⅡ和AVP的快速脱敏;用PAO抑制膜受体的内在化只能短暂抑制脱敏的发展,提示用膜受体数目的下调说不能完全解释同源脱敏;血管对AⅡ和AVP脱敏后VSMC细胞膜电压依赖性钙通道功能无改变;CA对AVP脱敏后GTPγS的量-效曲线下移,说明有G蛋白的变化,但这种变化并非G蛋白的亲和性改变;SHRsp之CA平滑肌对AⅡ和AVP的快速脱敏并未减弱,但对PE却表现为快速脱敏,这是我们首次发现的一个非常有趣的现象。

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Lao Qiu is the Chairman of China Qiuyang Translation Group and the head master of the Confucius School. He has committed himself to the research and promotion of the classics of China.

老秋先生为中国秋阳翻译集团的董事长和孔子商学院的院长,致力于国学的研究和推广。