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Recent studies found that ischemic brain damage is resulted from many reasons such as functional rearrangement of glia cells, an ion balance disorder, lipide peroxidation induced by free radicals, and changes of neurotransmitters.

许多继发性因素,如缺血后神经胶质细胞功能的重新安排,离子平衡紊乱,自由基引起的脂质过氧化损伤,以及神经递质的改变等可诱导神经细胞死亡,继而导致脑损伤,但有关缺血性细胞死亡机制目前还无定论。

Neu- roleptics such as Haloperidol and Tiapide might increase theta waves of the anterior and medius areas of the head of brain electrical back- ground activity of children with TS, and affect their memory func- tion, but not affect their intelligence, personality and behavior.

氟哌啶醇和泰必利等精神抑制药物可能使TS患儿头前中部区域的脑电背景活动θ波增多;并对TS患儿的记忆功能可能产生一定的影响,但对TS患儿的智力、个性和行为无明显影响。

By using the several neuroradiologic skills, we can be offered the richable, nonaggressive, direct information to the clinical and experimental neurology researcher, make progresses of the two courses tightly.

利用多项神经影像学技术,优化检查序列,可为临床及实验性脑卒中研究提供丰富的、无创性的、直接的信息,使神经科临床治疗与影像学诊断紧密地结合起来。

Mutant mice than in wild-type controls, and tetrodotoxin or bicuculline application abolished the difference between the genotypes. Studies on human oligodendroglioma cells revealed that GABA played a protective role on Ca〓 overload induced by OGD or glutamate and phaclofen, GABA〓 receptor antagonist, could significantly block the protection.

结果表明:①电凝大脑中动脉后Ca〓2.3-/-鼠脑梗死率和缺血后运动障碍明显重于Ca〓2.3+/+鼠;②Ca〓2.3-/-鼠海马脑片CA1区缺氧后钙超载明显高于Ca〓2.3+/+鼠;③Na〓通道阻滞剂TTX和GABA〓受体阻断剂bicuculline可显著缩小遗传表型之间的差异;④GABA对缺氧无糖及谷氨酸所致的人胶质细胞瘤细胞Ca〓超载有明显的保护作用,此作用可被GABA〓受体阻断剂phaclofen拮抗。

Results: The results showed that NOS positive neurons existed in all the auditory afferent nucleus while NOS negative neu-rons existed in the superior olivary nucleus. Most of NOS positive neurons in CNC were located in the posterior ventral cochlear nu-cleus ,which were round or oval bipolar neurons. NOS positive neurons were also found in potine widely.

结果:在脑桥的各级听觉传入核团,均有NOS阳性神经元,而上橄榄复合体无NOS阳性神经元;耳蜗核内NOS阳性神经元,主要集中在后腹侧核,为圆形或椭圆型双极神经元;下丘的臂内侧核NOS阳性神经元呈小的、圆形细胞。

Methods Eight cases of cerebral sparganosis treated at Huashan Hospital between 1982 and 1997 were analyzed retrospectively.

结果本病的病理特点为:1蚴虫虫体为实体,无体腔,具特征性体壁;2蚴虫虫体内散在分布的同心圆性圆形或椭圆形的石灰小体及单个肌纤维;3脑内有新旧不一的多发性小脓肿。

Methods: NG108-15 cells were cultured in vitro at 37℃in a humidified atmospherecontaining 5%CO_2. Aβ_(25~35) fragment was dissolved with deionized distilledwater and aged for 4 days at 37℃. The cells were exposured to 5μmol/LAβ_(25~35) for 24h to establish the cell model. Twelve rabbits were divided intotwo groups at random, and garaged with MWD or physiological saline controlrespectively for 7 days to collect two kinds of cerebrospinal fluid, theyare CSF from rabbits treated with MWD and CSF from rabbits treated withphysiological saline.

NG108-15细胞在37℃、体积分数为5%的CO_2培养箱中培养,Aβ_(25~35)溶解于双蒸水中,置于37℃培养箱中老化4d,使其寡聚,毒性增强,细胞被置于浓度为5μmol/L的Aβ_(25~35)中作用24h,建立起AD细胞模型。12只清洁级大耳白家兔购于华中科技大学同济医学院动物中心,将其随机分成两组,分别给与等量的加味温胆汤和生理盐水灌胃7d,末次给药后1h内用水合氯醛将给药组白兔麻醉,1.2ml/kg,无菌条件下用7号注射针头从枕骨大孔处垂直进针,抽取清亮含药脑脊液。

Three days after local cerebral infarction , the amounts of catecholamine-containing varicosities and the concentrations of CA in the varicosities in cortices of both sides were markedly reduced, and an aggregation of a large amount of CA granules which were of different fluorescent feature from tha...

局壮性脑梗塞三天后,双侧大脑皮质内CA膨体的数量与膨体内CA的浓度均显著减少,梗塞灶边缘区可见大量CA颗粒聚集,其荧光特征与正常皮质内的CA颗粒不同;双侧大脑皮质内的去甲肾上腺素含量显著减少,多巴胺含量无明显变化。

DATA SYNTHESIS: From the synthesis materials we found that there was little progress on the drug treatment of muscular spasm of cerebral palsy in recent years. The main drugs for treatment still were valium, baclofen, tizanidine, anhydrous alcohol, phenol, A-type borulinus toxin etc. common used drugs.

资料综合:综合资料发现近几年脑性瘫痪肌痉挛的药物治疗进展不多,治疗的主要药物仍然是苯甲二氮草、巴氯芬、替扎尼定、无水乙醇、苯酚、A型肉毒毒素等常用药物,给药的途径主要有口服、鞘内注射或肌肉注射。

Methods Clinical data of 104 cases with SCI by shown on CT and MRI in our hospital from 2004 to 2005 were presented retrospectively with literature review.Results There were 239 cerebral infarctions in this group.

分析我院从2004~2005年确诊的104例经头颅CT和MRI扫描证实的无症状脑梗死的临床资料,并进行相关文献复习。

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