无脑的

The EAE rats were induced by injecting subcutaneously an emulsion of GPSCH and CFA. In addition, each rat received an intracutaneous injection of pertussis. Albumin in serum and CSF samples was examined on the days of 4,6,8,10,12,14,16,18 and 20 p.i.. The integrity of BBB was assessed by caculating CSF to serum albumin quotient. At the same time the brains, spinal cords, thymus and inguinal lymph nodes were removed for paraffin sections cutting. These sections were used for HE staining and ICAM-1 semiquantitative immunohistochemical staining. The results showed as follows:1. None of EAE rats on days 4,6 and 8 p.i. showed clinical signs whichbecame apparent on day 10 p.i.(2.33±0.76; n=6). On days 12 and 14 p.i.

检测p.i。第4天、6天、8天、10天、12天、14天、16天、18天、20天血清和CSF中ALB含量，其CSF／S ALB比值作为评价BBB损害的指标；同时段取动物脑、脊髓、胸腺和腹股沟淋巴结制成石蜡切片行HE染色和ICAM-1半定量免疫组化分析，结果显示如下： 1、EAE大鼠p.i.4-8天无任何临床表现；p.i.10天症状开始明显，症状评分为2.33±0.76(n=6)；p.i.12-14天为发病高峰期，症状评分为3.75±0.54(n=12)，病情由最初的活动减少，体重减轻逐渐发展为肢体无力、瘫痪，共济失调，甚至濒死状态；p.i.16天大部分动物症状开始缓解，评分为2.08±0.66(n=6)；p.i.20天疾病症状完全消失。

Most common CT finding is cerebral atrophy, followed by low density parenchymal lesions without mass effect.

最常见的CT表现是脑萎缩，并低密度的实质性病灶，无占位效应。

No effect of temperature was observed in 1 and 2 week-old rats.

温度对1周和2周龄乳鼠的海马脑片tau蛋白的表达无影响。

The patient showed atrophy in frontal and temporal lobe on regular MRI, significantly reduced amount of Nacetyl aspartic acid、cholineand creatinecompared with contralateral on MRS , remarkably decreased blood flow in the left temporal polar and front part of fontal lobe compared with contralateral on PWI. There were decreased association fibers between Broca and other regions meanwhile no association fibers were found between triangular area and wernicke region on DTI. The fibers projecting to opercular part of frontal lobe via archiform fibers were lessened. The mean FA and fibers of Broca and Wernick regions were less than that of the healthy subjects.

常规MRI显示左侧额叶及颞叶萎缩；磁共振波谱分析显示左侧颞叶和额叶N乙酰天门冬氨酸、胆碱、肌酸含量较对侧明显减低；磁共振灌注成像显示左侧颞极及额前部的血流量较对侧减低；弥散张量成像显示左Broca区与其他脑区间纤维联系减少，三角区与Wernicke区无纤维联络，左侧Wernicke区通过弓状纤维到达额叶岛盖部的纤维减少，Broca及Wernicke区平均FA及纤维束较正常人减少。

Results The TCD manifestations of patients with semicoma have no characteristic change.

结果 浅昏迷患者的TCD表现无特征性改变，当出现中度昏迷或深昏迷时，颅内幕上结构损害患者TCD表现与文献报告相似，颅内幕下结构损害、代谢及弥漫性脑病患者大脑中动脉血流速度改变不明显，但死亡的18例病人中有13例出现了收缩期末血流速低于舒张期末血流速。

Results The TCD manifestations of patients with semicoma have no characteristic change. In moderate or deep coma patients, who have intracranial supratentorial injury, the TCD manifestations are similar to related documents. The blood flow velocity of middle cerebral artery of patients with subtentorial brain injury or metabolic or diffused brain diseases have no obvious change. But in the 18 dead cases, there are 13 whose blood fiow velocity of end systolic stage are lower than those of end diastolic stage.

结果 浅昏迷患者的TCD表现无特征性改变，当出现中度昏迷或深昏迷时，颅内幕上结构损害患者TCD表现与文献报告相似，颅内幕下结构损害、代谢及弥漫性脑病患者大脑中动脉血流速度改变不明显，但死亡的18例病人中有13例出现了收缩期末血流速低于舒张期末血流速。

At the same time, monitor the TCD characteristics, observe the frequency spectrum form and the blood flow velocity in cranial vessels. Results The TCD manifestations of patients with semicoma have no characteristic change. In moderate or deep coma patients, who have intracranial supratentorial injury, the TCD manifestations are similar to related documents.

结果 浅昏迷患者的TCD表现无特征性改变，当出现中度昏迷或深昏迷时，颅内幕上结构损害患者TCD表现与文献报告相似，颅内幕下结构损害、代谢及弥漫性脑病患者大脑中动脉血流速度改变不明显，但死亡的18例病人中有13例出现了收缩期末血流速低于舒张期末血流速。

The main peaks of the EEG power spectra were in delta and theta frequency range. In the stage of ethanol exposure, the rats exhibited much more act of attack than the control, the alpha waves of EEG decreased, while the delta waves increased. The EEG power spectra analysis showed the delta power increased and the theta power decreased. In the stage of ethanol withdrawal, the rats showed some withdrawal behaviors such as wet dog shakes, sniffing, groomingand tonic-clonic seizures for audiogenic stimulus. Spikes and spike-slow waves were found in the EEG. In power spectra analysis, the delta power decreased while the alpha and the theta power increased, the EEG frequency band moved to the high-frequency rang. These changes were found obviously on the sixth day and disappeared on the 1 Oth day after the ethanol was removed.

本研究发现：1、对照组大鼠行为无异常，伏核EEG以α节律为主，散在出现δ和θ节律；功率主峰在δ和θ频段范围，整个过程中未发现手术对伏核EEG及脑电功率谱有影响。2、在慢性饮酒过程中，大鼠攻击性行为增加，伏核 EEG的α节律明显减少，散在出现的高幅慢活动δ波逐渐增多，功率谱分析表明δ频段功率百分比明显增加，而θ频段功率百分比明显减少，总功率减少。3、停饮后，大鼠出现湿狗样抖动、打喷嚏等撤药综合症，并且高频声音刺激能引发惊厥；伏核EEG出现棘波和棘慢综合波，并持续增多，功率谱分析显示δ频段功率百分比 5 南京医科大学硕士学位论文逐渐减少，而0和以频段功率百分比逐渐增加，总功率增加。

Objective: Porcine enteric virus is a pathogen, which causing porcine enterovirus infection, such as porcine encephalomyelitis, reproductive failure, pneumonia, diarrhea, cardiopericarditis, myocarditis, dermal lesion, and so on . It is an important infection disease that can damage the pig-raising industries. In this study, porcine enterovirus was isolated and identificated in pocine kidney primary cell.

猪肠道病毒感染是由猪肠道病毒(Porcine enterovirus，PEV)所引起，有多种不同的临床表现，如猪脑脊髓灰质炎、生殖障碍、肺炎、下痢、心包炎和心肌炎、皮肤损伤及无症状等，是一种危害养猪业的重要传染病。

RESULTSThe branches of aortic arch are the left and right innominate artery in pate of mini-pig.

结果小型猪主动脉弓部向头颈部分支为左、右无名动脉；双侧颈内动脉均来自右无名动脉，故右无名动脉对脑底供血十分重要；双侧有沿脊柱向尾侧走行的折返动脉；胸主动脉背侧由胸6至胸14平面共发出8条肋间动脉，为胸腰脊髓的主要供血动脉；无腰大动脉。

It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发，分析对称连杆曲线上鲍尔点的产生条件，提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品，年生产总值3000万美元，产品价廉物美、选料上乘、质量保证，深受国内外客户的青睐