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To investigate whether syrinx should by treated before correction in patients with scoliosis complicated by syringomyelia without neurologic impairment.

探讨伴脊髓空洞症的脊柱侧凸患者在无神经症状且达到矫形指征时应否于矫形之前对脊髓空洞进行外科处理。

Results:(1) cerebrovascular syphilis 1 case,tabes dorsalis 2 cases;(2) Inall cases,Serum and cerebrospinal fluid syphilis antibody reaction showed positive; CSF protein content was increased significantly,and cells increased (3) MRA and DS...

结果(1)脑血管梅毒1例,脊髓痨2例;(2)3例血和脑脊液的梅毒抗体均为阳性;脑脊液蛋白含量增加、细胞数增多;(3)脑血管梅毒患者MRA及DSA显示左大脑中动脉M1段闭塞;左大脑前动脉及左大脑后动脉通过皮层支向左大脑中动脉供血区代偿供血;(4)2例脊髓痨患者头颅及胸髓MRI无特殊发现,肌电图及周围神经活检不支持周围神经受损。

Results:(1) cerebrovascular syphilis 1 case, tabes dorsalis 2 cases;(2) mall cases. Serum and cercbrospinal fluid syphilis antibody reaction showed positive; CSF protein content was increased significantly, and cells in creased (3) MRA and DSA of cerebroascular syphilis show that Mi segment of the left middle cerebral artery is blocked. The left posterior cerebral artery and the left anterior cerebral artery compensate blood supply for the left middle cerebral artery through the conical branch.(4) MRI of head and thoracic cord was normal in 2 cases of tabes dorsalia. Result of EMG and biopsy of suml nerve not manifest damage of peripheral nerveous system.

结果:(1)脑血管梅毒1例,脊髓痨2例;(2)3例血和脑脊液的梅毒抗体均为阳性;脑脊液蛋白含量增加、细胞数增多:(3)脑血管梅毒患者MRA及DSA显示左大脑中动脉M1段闭塞;左大脑前动脉及左大脑后动脉通过皮层支向左大脑中动脉供血区代偿供血;(4)2例脊髓痨患者头颅及胸髓MRI无特殊发现,肌电图及周围神经活检不支待周围神经受损。

It is thought that there's an independent neural pathway through which itch is transferred mainly by peripheral unmyelinated C fibers to the most superficial part of dorsal horn, then the lamina Ⅰ spinothalamic tract ascends to the thalami and further projects to the cortex.

目前认为存在独立的痒觉神经传导通路,主要由外周无髓C纤维传入信号至脊髓背侧角的最浅层,Lamina Ⅰ脊髓丘脑束上行至丘脑,进一步投射至皮质区。

Especially, the number of type Ⅰ complex terminals which come from unmyelinated afferent fibers recovered to the level of unoperated side. It indicates that morphine may promote the collateral sprouting and synaptic reinnervation of primary afferent fiber, unmyelinated afferent in particular. 4. Although the collateral sprouting and synaptic reinnervation were shown also in spinal cord of operated side in 34 days spared root rats, they were slower than that of morphine spared root group.

表明吗啡促进了备用根初级传入纤维,特别是无髓纤维更快地向L〓脊髓段侧支出芽,稍后在L〓平面脊髓内侧支出芽以及突触重建。4、34天备用根大鼠术侧脊髓内也有侧支出芽和突触重建,不过侧支出芽的速度要比吗啡组慢。5、电镜定量结果也显示,吗啡备用根大鼠和备用根大鼠术侧备用根的无髓纤维数比备用根大鼠非手术侧的分别增多60%和42%。

But in 24h experiment group, the decreases of the indexes are not statistically significant. Conclusion Early application of rhEPO could lessen the lesion of neuromotor function and secondary pathology change. The protection is partially due to the reduction of expression of Caspase-3 and neural cell apoptosis.

结果:与对照组相比,脊髓损伤后rhEPO1小时,6小时处理组神经运动功能和继发性病理损害明显改善,脊髓Caspase-3的表达明显下降(P 0.01);而术后24小时组与对照组相比,脊髓神经细胞凋亡指数及Caspase-3的表达下降均无统计学意义。

Result Compared to concurrent control groups, neuromotor function are significantly improved in 1h and 6h experiment group. The indexes of neural cell apoptosis decreased significantly (P 0.01). But in 24h experiment group, the decrease of the index are not statistically significant. Conclusion Early application of rhEPO could lessen the lesion of neuromotor function. The protection is partially due to the reduction of neural cell apoptosis.

结果:与对照组相比,脊髓损伤后促红细胞生成素1小时,6小时实验组神经运动功能明显改善,脊髓神经细胞凋亡指数均明显下降(P 0.01);而术后24小时组与对照组相比,脊髓神经细胞凋亡指数的下降无统计学意义结论:早期应用外源性EPO对脊髓不完全损伤后引起的神经运动功能损害具有保护作用,此种保护作用可能与EPO能够减少神经细胞凋亡有关。

Sensory impairment and urinary dysfunction also had developed, and paraparesis persisted after the hypokalemia was corrected during hospitalization. An optokinetic nystagmus test showed bilateral sick waves and at the same time a cerebrospinal fluid analysis was normal. A blood examination disclosed borderline anti-nuclear antibodies and an elevated serum IgG level. Her cervical spinal cord showed mild swelling and contrast-enhancement when examined by magnetic resonance imaging. Neither a brain stem nor an optic nerve's lesion was found. Based on the above, acute transverse myelitis was diagnosed. All the symptoms present in the patient relieved gradually after 5-days of pulsed intravenous methylprednisolone therapy.

一50岁女性,因为眩晕、前额头痛、视力模糊、恶心、呕吐及两侧下肢无力而求诊,於低血钾矫正后,两侧下肢无力依然持续,并发生胸部以下感觉缺损及排尿困难等现象,视运动性眼振检查显示两侧波形障碍,脑脊液检查正常,血液学检查显示抗核酸抗体及血清IgG指数偏高,显影剂增强磁振造影显示颈段脊髓肿大且略为显影,并无脑干或视神经的病灶,诊断为急性横断性脊髓炎,给予静脉注射类固醇后症状逐渐缓解。

The lumbar spinal cord in normal rat was immunohistochemically stained with ABC method using HAP1B antibody. Under light microscope, it was observed that HAP1 immunoreactants is mainly distributed in the pericaryon and neuropil in superficial lamella of the gray nucleus with little or no expression in other layers of the spinal horn. The substantia alba show no HAP1B immunoreactants.

对正常大鼠腰段脊髓进行HAP1B的ABC法免疫组织化学染色,光镜下观察显示,HAP1免疫反应产物主要分布在脊髓灰质背角浅层神经元胞体和神经毡内,灰质其他各层无或极少HAP1B表达,白质内未见明显HAP1B免疫反应产物。

This study is aimed to address the question whether the early discharges can affect thesilent period and modulate the late discharges and to investigate the possiblerole of dysfunction of primary myelinated afferents in generation of chronicpain. In addition, we also investigate the effect of the precedingA-conditioning stimuli with graded numbers on the late discharges of WDRneurons evoked by a following nociceptive test stimulus that activates bothA- and C-fibers.

在定义WDR神经元的反应特性时,通常用一个短促的电刺激刺激相关的神经干,激活A及C类纤维,这时可记录到一个反映有髓纤维传入的高频短促的早成分放电,接着是一个无放电的宁静期,最后是C纤维激活所诱发的晚成分放电,这种放电形式有别于脊髓背角的其它神经元。

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