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Thymosin, which was firstly purified from noncellular extraction solution of bovine thymus by Goldstein in 1965, has been researched for more than 150 years.

人类对胸腺素的研究已有150多年的历史。1965年由Goldstein等从小牛胸腺的无细胞浸出液中,经初步纯化得到了胸腺素。

Among them VLP- 1 100 mg / kg d acts best, the transition rate of achroacyte reach 65.5013%, each VLP -1 dosage has apparent effects to the live weight gain of normal rats' immunization organic, VLP-1 50 mg / kg d and 100 mg / kg d have sorely significantly live weight gain function to thymus and milt, when VLP-1 is 25 mg / kg d, the thymus weight increase sorely significantly while milt increase not too much.

各VLP一1剂量对正常小鼠免疫器官的增重均有明显作用,其中VLP一1在50 mg/kg.d、100 mg/kg·d剂量下对胸腺、脾脏有极显著地增重作用,在25mg/kg 。d 剂量下极显著地增加胸腺重量,而对脾脏增重无影响;粗多糖仅在100mg/kg·d 剂量下对脾脏增重有明显作用外,其余各剂量对正常小鼠胸腺、脾脏增重无影响。

METHODS AND RESULTS: Human smooth muscle cell and fibroblast cell sheets were harvested from temperature-responsive culture dishes and transplanted into ischemic hind limbs of athymic rats.

方法和结果:人类平滑肌细胞和成纤维细胞从温度敏感的培养皿中获得移植到无胸腺鼠的缺血下肢。

There were no cells on the SIS as control. They were implanted subcutaneously in the dorsa of the athymic mice. The implants were harvested after in vivo incubation for 4, 8 and 12 weeks.

将复合培养细胞与单纯材料分别植入无胸腺裸鼠皮下,扫描和透射电镜观察植入前和植入后4、8、12周成骨细胞、血管生成的变化过程。

The athymic recipients were reconstituted with 3.5 x 10(7) or 5 x 10(7) presensitized CD4+T-lymphocytes.

采用3.5×107或 5×107 CD4+T细胞预先致敏无胸腺的受者。

Islet responses to glucose challenge were evaluated in vitro and isolated islets were used successfully to cure streptozotocin-induced diabetes in athymic mice.

在试管内试验兰氏小岛以葡萄糖测试的反应之评估,及分离之兰氏小岛成功的治愈 streptozotocin 诱发糖尿病之无胸腺小鼠。

Cardiomyocyte sheets were then layered and transplanted into the subcutaneous tissues of athymic rats.

然后,心肌细胞片分层移植到无胸腺大鼠皮下组织。

The expression of Cat V was significantly raised in the epithelial-rich and mixed cell thymomas when compared with that in the lymphocyte-rich ones. No statistically significant difference was found on the variables such as perioperative myasthenic crisis, sex or age of patient, duraton of sickness and expression of Cat V.

上皮细胞型(75.00%)和混合细胞型(85.00%)胸腺瘤中Cat V阳性表达率显著高于淋巴细胞型(21.21%)(P.01),而上皮细胞型与混合细胞型之间差异无统计学意义;良性与恶性胸腺瘤中Cat V阳性表达率差异无统计学意义;男性患者与女性患者之间、35岁以上患者与以下患者之间胸腺瘤中Cat V阳性表达率差异均无统计学意义。

The biological behavior of thymoma with or without capsule might not be assessment standard for benign or malignancy.

有包膜的胸腺瘤和无包膜的胸腺瘤的生物学行为不是判断胸腺瘤良恶性的最佳指标。

The thymuses of ZD rats appeared atrophy, with thin cortex, unclear boundary of thymus cortex and mudulla, and decreased thymocytes.

3显微镜下观察,ZD组大鼠胸腺明显萎缩,皮质变薄、疏松,皮、髓质分界模糊,胸腺细胞明显减少,胸腺小体的数量也明显减少。补锌后,ZS组胸腺的病理结构有明显恢复,与ZA〓组无明显差异。

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