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无精子症

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Methods: A cytogenetic karyotype analysis was performed in 174 cases of azoospermiaand oligospermia.

对174例少精子症、无精子症的病人进行染色体核型分析。

The results indicated that PCR assay can be used in the detection of YRRM1 gene and the method is very useful for clinical diagnosis of azoospermia ...

结果表明,应用该方法检测YRRM1基因片段是切实可行的,对无精子症和严重少精子症患者的病因诊断具有一定的应用价值

Apoptosis plays a pivotal role in the spermatogenesis.Disequilibrium of apoptosis in germ cells is one of the reasons for azoospermia.

生精过程中细胞凋亡过程对维持正常的精子生成至关重要,该过程的失衡是导致少精子无精子症的重要机制之一,已受到广泛关注。

Objective To investigate androgen receptor mRNA expression in severe oligozoospermia or azoospermia patients.

目的研究严重少精子或无精子症患者外周血中雄激素受体mRNA的表达。

Microdeletion of AZF gene is one of the causes leading to azoospermia and severe oligozoospermia, which has a close relation with the development of sperm defect.

AZF微缺失是引起特发性无精子症和重度少精子症的原因之一,与男性精子缺陷发生密切相关。

Azoospermia, oligospermia and idiopathic infertility should be based on sex hormone drugs for endocrine therapy.

无精子症,少精子症及特发性不育,应以性激素类药物作内分泌治疗为主。

There are many factors resulted in male infertility. Majority is associated with sperm count, morphology and motility. Men with oligospermia, asthenospermia, teratozoospermia and azoospermia account for 20~25% of the cases.

引起男性不育的因素有很多,大部分与精子的数目、形态及运动功能有关,其中由于精子生成过程的停滞或障碍所导致的少精子、弱精子、畸形精子和无精子症占男性不育的20~25%。

Objective To evaluate the frequency of microdeletions in the long arm of Y chromosome of idiopathic infertile males with azoospermia and oligospermia in Xinjiang province in China and to investigate the difference of Y microdeletion frequencies between two nations.

目的评估新疆地区汉族、维吾尔族不明原因无精子症和严重少精子症男性患者Y染色体长臂微缺失的频率,探讨不同民族间Y染色体长臂微缺失发生率的差异。

Objective: Retrospective study of the results of ICSI(intracytoplasmic sperm insemination)with frozen sperm obtained by PESA( percutaneous epididymal sperm aspiration ) was performed in 27 patients.

目的:回顾性分析27例无精子症患者经皮附睾穿刺取精术所获精子冷冻复苏后行卵细胞胞质内单精子注射治疗后的效果及妊娠结局。

Ninety-three patients with forty-two azoospermia and fifty-one severe oligozoospermia were recruited in present study. Y chromosome microdeletions were screened by detection of four locus SY84, SY134, SY255 and SPGY1 gene spaning the AZFa, AZFb and AZFc subregions of Y chromosome. The total incidence of Y microdeletions was 16%( 15/93 )in present study. Eight men in 42 patients with azoospermia had Y microdeletions, of whom 6 were AZFc deletion and 2 were AZFb deletion.

通过对93例男性不育(42例无精症和引例严重少精症)患者,Y染色体 SPGY基因、AZFa-SY84、AZFb-SY134和 AZFc-SY255位点缺失情况的研究,我们发现男性不育患者 Y染色体微缺失的发生率为 16%( 5旧3人 42例无精子症患者中,有8例存在Y染色体微缺失,其中6例为AZF。

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