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无精子症

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Results The total aberrantion rate of chromosome is 26.7%(23/86);Compared the normal controls,in azoospermic patients,Serum FSH、LH levels increased,The rate of T/LH decreased.and there is a very significant difference(P%26lt;0.05);The resemble results is detected in different outcome in PESA.

结果摘要:86例无精子症患者中异常核型23例,占总例数26.7%;和正常对照组相比较,无精子症组血清FSH、LH升高,T/LH比值下降,差异有显著性(P%26lt;0.05);PESA能抽吸到精子组比不能抽吸到精子组的FSH、LH偏高,T/LH下降(P%26lt;0.05)。

Results OA and NOA were diagnosed in 82 (55%) and 67 (45%) patients, respectively.

结果 PESA/TESA结果显示,149例中梗阻性无精子症82例(55%),非梗阻性无精子症67例(45%)。

Methods Male infertility couples from October 2006 to July 2008 were chosen and divided into ICSI group and TESA+ICSI group. ICSI group were 584 oligozoospermia cases with alive normal sperm in spermatic fluid. TESA+ICSI group were 54 obstructive azoospermia cases with alive normal sperm in testicle. Two groups were treated with ICSI after wives obtained oocytes by ovarian stimulation.

选择2006年10月~2008年7月因男性不孕症夫妇行ICSI治疗的患者638例分成两组,ICSI组和TESA+ICSI组,ICSI组为自行排精后精液内可以找到正常形态活精子的少精症患者行ICSI治疗584例,TESA+ICSI组为梗阻性无精子症患者经睾丸穿刺找到睾丸内形态正常活精子行ICSI治疗共54例,两组女方均给予超促排卵用药获取卵母细胞。

To investigate the relationship between spermatogenesis disorder and genetic defects of patients with azoospermia or severe oligospermia.

探讨无精子症和严重少精子症患者的遗传缺陷与精子生成障碍的关系。

Objective To detect the abnormal YRRM gene in azoospermia and to explore the pattern of YRRM gene in Chinese men.

目的 探索无精子症因子基因的候选基因之一YRRM基因在无精子症患者中的异常,了解中国人群的YRRM基因的形式。

Methods Detect the chromosome and serum reproductive hormones of 86 azoospermia cases and 35 normal controls.

检测86例无精子症患者与35例正常对照男性的外周血染色体、血清生殖激素(FSH、LH、T、PRL、T/LH);分析无精子症患者的生殖内分泌激素水平的变化。

Methods 45 patients with nonobstructive azoospermia, 40 patients with obstructive azoospcrmia and 40 healthy subjects were involved in this study. Serum FSH, LH and T levels were measured by chemiluminescence immunoassay, and serum INHB was measured by sandwich enzyme-linked immunosorbent assay.

采用化学发光免疫分析法测定45例非梗阻性无精子症、40例梗阻性无精子症及40名正常生育男性血清FSH、LH及T的浓度,以双抗体夹心酶联免疫吸附试验测定血清INHB水平。

Objective To evaluate the influence of serum follicle stimulating hormone, luteinizing hormone and testosterone levels to the type of azoospermia and the predictive value of inhibin B level as an indicator of the presence of testicular spermatozoa in patients with nonobstructive azoospermia.

目的 探讨血清促卵泡成熟激素、黄体生成素及睾酮等生殖激素水平对无精子症分型以及血清抑制素B水平对非梗阻性无精子症患者睾丸精子存在与否的预测价值。

Objective To obtain information on the application value of percutaneous epididymal sperm aspiration and percutaneous testicle sperm aspiration in the differentiating diagnosis of obstructive and nonobstructive azoospermia.

目的探讨经皮附睾精子抽吸术及经皮睾丸精子抽吸术在无精子症鉴别诊断中的应用价值。方法采用PESA或PTSA对梗阻性无精子症组37例及非梗阻性无精子症组28例进行附睾或睾丸取精,细胞学涂片进行分析。

According to the results of semen examination, can be classified as azoospermia and severe oligospermia, oligospermia, infertility and normal sperm count, more than sperm and sperm can not afford such disease.

根据精液检查的结果,可分类为无精子症、重度少精子症、少精子症、精子数正常性不育症、多精子症以及精子无力症等。

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