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Hybrid schwannoma/perineuriomas have no evident association with neurofibromatosis and rarely recur. The pathogenetic basis of the dual pattern of differentiation in these lesions remains poorly understood at this time.

混合性神经鞘瘤/神经束膜瘤与神经纤维瘤病无明显关系,且罕有复发,其瘤组织双重分化的发生机制目前仍不清楚。

The perfect neurosurgery operation anaesth is fast and equability,keep good sedative and analgesia effects,not increase intracranial pressure and cerebral metabolism,no nervous system adverse effects,patients awake fast after use anesthetic,and not excited or psychiatric symptom or respiratory depression or remain drug action.

天津市宁河县医院麻醉科,天津 300060)摘要:理想的神经外科手术麻醉要求诱导过程迅速平稳,维持过程镇静、镇痛好,不增加颅内压和脑代谢,无神经系统不良反应,停药后清醒迅速且无兴奋及精神症状,无呼吸抑制及残余药物作用。

To isolate forebrain and hindbrain of human fetuses about 9 weeks and 12 weeks from spontaneous abortion. Neural stem cells were cultured in special culture medium and were compared with growth characterization.The differentiation from these neural stem cells was investigated in both a fetal bovine serum-containing and a non-supplemented,serum-free basal medium.

材料与方法:利用神经干细胞的条件培养基,对从9周和12周胚龄的自然流产胎儿分离的前脑、后脑进行神经干细胞培养,比较其生长特性,并分别观察在无生长因子的基础培养基以及含有胎牛血清的培养基中神经干细胞的分化情况。

With regard to patients' function, a positive correlation between the physical component summary and mental component summary of SF-36. It also showed significant differences in function between patients with and without peripheral neuropathy symptoms.

在糖尿病周边神经病变患者生活品质部分,本研究结果发现有周边神经病变感觉不适症状的糖尿病患者在生理相关生活品质及心理相关生活品质两个部份的得分皆较有周边神经病变但无感觉不适症状的患者来得低(p<。01)。

The expression of nestin antigen, NSE and GFAP were identified by immunohistochemistry, and the number of NSE-positive cells and GFAP-positive cells were dividedly counted.

结果大鼠胚胎神经管神经上皮干细胞在无血清培养基中可形成大量呈nestin抗原阳性细胞构成的神经球,经传代有血清培养后分化为NSE阳性和GFAP阳性细胞,其中NSE阳性细胞占细胞总数的47.7%,GFAP阳性细胞占细胞总数的39.8%。

The sensory loss in donor region was oberserved only lateral part of the foot beneath the lateral malleolus and a small part of the anterior aspect of the ankle.

神经供区感觉缺失在腓肠神经者只出现在外踝下方足的外侧区,在隐神经者出现在踝前方的小片区域,对下肢的功能无影响。

[Objective] To analyze the outcome of internal fixation for occipitalization with atlantoaxial joint dislocation by posterior decompression and occipitocervical fusion [Method] From December 2005 to June 2007,8 patients with occipitalization and atlantoaxial joint dislocation received removal of the posterior arcus of atlas and the enlargement of the posterior edge of the foramen magnum after skull traction performing for an average of 135 daysAll patients were operated on by posterior craniocervical fusion using cervifix internal fixation system and autologous ilium graftsThe clinical efficacy after operation was analyzed by Japanese Orthopaedic Associationneural function score [Result] All the patients were followed up from 6 months to 2 years, average of 15 monthsNo complication was foundAtlantodental interval was 5~9 mm before and 4~6 mm after skull tractionAtlantoaxial joint dislocation didn't completely reducedThe neurological defects were improved to some extents according to the JOA scoreImageology showed all patients had full decompression and bony fusionThe loosening or broken internal fixation was not found [Conclusion] Posterior decompression and fusion is a feasible method for the treatment of occipitalization with atlantoaxial joint dislocation,and the clinical effect is satisfactory

分析后路减压枕颈融合内固定术治疗合并寰枢关节脱位的寰椎枕骨化临床疗效。[方法]2005年12月至2007年6月间,对8例合并寰枢关节脱位的寰椎枕骨化患者在行颅骨牵引治疗一段时间(12~16 d,平均135 d)后采用枕骨大孔后缘扩大,寰椎后弓切除减压取自体髂骨枕颈融合Cervifix系统内固定术,手术后采用日本骨科学会神经功能评分分析临床疗效。[结果]8例患者随访6个月~2年,平均为15个月。8例患者无一例出现术后并发症,术前寰齿前间隙为5~9 mm,经颅骨牵引后为5~7 mm,寰枢关节脱位未能完全复位。手术前后JOA评分示神经症状均有不同程度恢复,影像学检查示枕颈区减压充分植骨区获得骨性融合,无一例出现内固定松动或断裂。[结论]合并寰枢关节脱位的寰椎枕骨化患者术前仔细评估影像学改变,采用颅骨牵引一段时间后行后路减压枕颈融合内固定术的治疗方案是合理可行的,且临床效果满意。

Several investigators have determined that placing the electrode parallel rather than perpendicular to the target nerve substantially increases the size of the lesion, thereby reducing the likelihood the treatment will miss or only partially coagulate the target nerve.234,235 After a literature review and cadaveric study, Lau et al.234 concluded the ideal electrode position is across the lateral neck of the superior articular process rather than the groove formed at the angle of the superior articular and transverse processes, as was used in most studies.159,160Other investigators have found the maximal lesion size to be reached within 60 s of lesion time,235–237 independent of whether the system is temperature or voltage controlled.238 Studies conducted in human myocardium have determined that irrigation fluid has either no effect or a slightly beneficial effect on lesion size.239 Hence, the use of LA to prevent procedure-related pain or steroid to reduce the incidence of neuritis184 should theoretically have no adverse effects on the efficacy of radiofrequency denervation.

一些研究者认为,将点击平行的置于目标神经比将其垂直置于目标神经增加了消融的范围,因而减少损伤可能使目标神经不被或部分被消融。Lau等回顾了文献中对尸体的研究,总结出理想的电极放置位置为上关节突颈部外侧而非常采用的上关节突与横突形成的沟。其他学者研究发现,不论系统是温度控制或电压控制,其最大的损伤范围都在60秒内达到。在心肌灌注的研究中,灌注液多损伤范围造成轻微或不造成损伤。因此,使用LA预防过程相关性疼痛或类固醇防止神经炎发生时,需理论上确保对射频消融效果无副作用。

Methods: Neuroepithelial stem cells derived from the embryonic neural tube of GFP transgenic mice were cultured and depurated in free serum medium containing B27, bFGF and EGF, and then they were directionally transplanted into the striatum of rats.

将GFP转基因鼠的胚胎神经上皮干细胞置于无血清培养基内纯化扩增,用巢蛋白免疫组织化学染色鉴定神经干细胞,将扩增后的含GFP基因的神经干细胞在立体定位仪下,定向移植到大鼠的纹状体内。

This experiment selects material E14d SD the big mouse SVZ nerve stemcell as well as P7d the SD big mouse internal ear stem cell, does nothave the blood serum complete culture medium raise through D-MEM/F12to cause its massive multiplication, a part carries on Nestin, NF,CNP, GFAP, MAP-2, Myosin, the P27 immunity group, proved the raise thenerve stem cell has many to the split up ON potential; Another partdyes EGFP after the extension to carry on the guinea pig internal earto transplant, after two weeks fills the class to take the cochleafixed slice observation, discovered has the stem cell ball group inthe internal ear survival, proved the nerve stem cellheterotransplantation the possibility and for transplants the stemcell migration differentiation repair hair cell damage the thoroughresearch accumulation experiment experience.

本实验取材E14d SD大鼠SVZ神经干细胞以及P7d SD大鼠内耳干细胞,通过D-MEM/F12无血清完全培养基培养使其大量增殖,一部分进行Nestin、NF、CNP、GFAP、MAP-2、Myosin、P27免疫组化,证明培养的神经干细胞具有多向分化的潜能;另一部分通过转染EGFP后进行豚鼠内耳移植,两周后灌流取耳蜗固定切片观察,发现有干细胞球团在内耳存活,证明神经干细胞异体移植的可能性并为移植干细胞迁移分化修复毛细胞损伤的深入研究积累实验经验。

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As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸,那乌黑、忧郁的眼睛,她便会相信,他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失

But because of its youthful corporate culture—most people are hustled out of the door in their mid-40s—it had no one to send.

但是因为该公司年轻的企业文化——大多数员工在40来岁的时候都被请出公司——一时间没有好的人选。