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In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis.
综合全部实验结果,本研究提示:夏季和低龄是托吡酯引起泌汗障碍的主要危险因素,而托吡酯剂量对泌汗(来源:A44B8787C论文网www.abclunwen.com)功能的影响较小;托吡酯可以抑制小鼠汗液的分泌,小鼠的年龄并不影响这种抑制作用,但托吡酯对小鼠体温无明显影响;托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗;托吡酯不影响汗腺形态及Na,K-ATP酶活性;汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关,而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。
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The experiment optimized the culture medium and conditions for PV 1 to yield the highest GABA: sucrose as carbon source,peptone and beef extract as complex nitrogen source,initial pH at 7.0,temperature at 30~34 ℃.The content of GABA was over 4 g/L in the optimum culture conditions.Thereby,i...
实验还对酸菜1号菌株的培养基和培养条件进行了优化:用蔗糖为碳源、蛋白胨和牛肉膏作为复合氮源、培养基初始pH为6.0、培养温度为30~34℃时该菌株发酵产GABA的量最多,发酵过程中的振荡培养(100 r/min)和静置培养对GABA的产量无明显影响;在最佳培养基组合和发酵条件下,发酵液中GABA含量可达4 g/L以上,表明利用乳酸菌进行富含GABA食品的生产是可行的。
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The present invention relates to a coating composition comprising; A at least one polyester oligomer prepared from reactants comprising a 20 60 wt.% of at least one polyol, b 5 30 wt.% of at least one polycarboxylic acid selected from the group of cyclic polycarboxylic acids, the esters or the anhydrides thereof, wherein the carboxyl groups are separated by 3 carbon atoms or less, and from the group of alpha , beta -saturated acyclic polycarboxylic acids, the esters or the anhydrides thereof, and c 20 60 wt % of at least one monocarboxylic acid, the sum of the wt.% indicated for the reactants,, and always being 100 wt.%, and the oligomer being a low-viscosity oligomer having a weight average molecular weight Mw of less than 5,000, and a hydroxyl number in the range of about 200 to about 400 mg KOH/g oligomer, and B at least one polyisocyanate.
本发明涉及一种包含如下组分的涂料组合物:A至少一种由包含如下成分的反应物制备的聚酯低聚物:a20-60wt%至少一种多元醇,b5-30wt%至少一种选自其中羧基被3个或更少碳原子隔开的环状多元羧酸、其酯或酸酐以及选自α,β-饱和的无环多元羧酸、其酯或酸酐的多元羧酸,以及c20-60wt%至少一种一元羧酸,其中反应物、和的wt%之和总是为100wt%,所述低聚物是重均分子量Mw低于5000且羟基值为约200-约400mg KOH/g低聚物的低粘度低聚物,以及B至少一种多异氰酸酯。
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It employs carbon dioxide as carbon source to replace traditional sugar, the concentration is controlled to be 2000- 3000ppm, takes light transmission, ventilating and water- proof fluoroethylene resin film as container, and gets tissue culture sprout and replanting sprout of chrysanthemum, which are characterized by largest plant height, largest leaf number, root number, longest root length and largest dry net weight of haulm and root, high rate of emergence and little pollution rate.
本发明提供了一种无糖培养菊花的方法,采用二氧化碳作为碳源,替代传统的糖,控制释放浓度为2000~3000ppm,采用透光性好、透气不透水的氟乙烯树脂膜为容器,在此种培养条件下,不同品种的菊花组培苗和组培后移栽苗在株高、叶数、根数、最大根长、茎叶部分和根部部分的干鲜重最大,出苗率高,污染率最低。
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Carbon-14 through the ring inference and reference "polar glaciers source of water theory" on its equivalent billion years of age, and the 2004 Antarctic expedition of 3000 meters from the polar ice-class source of water similar to the water is clean functional effectiveness can not Bacteria, naturally full of "active" role in the trend of high-Tour-organic marine biological activity of the best deep water, natural "green" Need for Water, high value-added applications, will become the 21st century "Water for Life" the new mainstream !
通过碳14的年轮推断和参考《极地冰川源水理论》它相当于上亿年的年龄,与2004年南极科考抽取的3000米极地冰川级源水类似,其水功能功效能是洁净无菌,充满自然"活性"作用的游离子有机态势高生物活性的海洋深层水的极品,自然"绿色"之水极品,极高的应用附加价值,将成为21世纪"生命之水"的新主流!
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Then, gasification experiments of high ash melting point coal with dry pulverized coal feeding were carried out on the gasification test system, the flame images were observed to validate the feasibility of flameless gasification inside the gasifier, temperature distributing inner the gasifier and syngas components were measured under different / atom ratio and steam/coal ratio conditions.
进而,建立煤粉气化炉的物理和数学模型,运用概率密度函数方法对高灰熔点煤在基于无焰氧化的煤粉气化炉内的气化过程进行了模拟计算,参照小试的试验工况,验证了气化炉模型;分析了不同氧碳原子比、蒸汽煤比和气化压力对高灰熔点煤气化特性的影响,并可视化地研究在典型工况下高灰熔点煤在该气化炉中气化过程,为进一步炉型结构和气化工艺的优化设计提供依据。
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It is prepared from titanium tetrachloride carried on an alcohol carrier that Mg and Li chlorides with molar ratio of 1:(2-20) are dissolved in alcohol, and by: co-dissolving Mg chloride and Li chloride in a low carbon alcohol and stirring at high speed in an inert medium to form micro-particles; reacting the said alcohol with titanium tetrachloride twice, adding organic acid polyester at first time, washing out uncarried titanium tetrachloride, and drying to obtain powdery pruduct.
它是由四氯化钛负载于将氯化镁和氯化锂共溶于醇形成的醇合物载体上组成,其中氯化锂与氯化镁的摩尔比为1∶2~1∶20。这种主催化剂组分的制备有两个步骤:(1)无水氯化镁和氯化锂共溶于低碳醇中形成醇合物,并在惰性介质中高速搅拌形成醇合物微粒;(2)醇合物与四氯化钛进行两次反应,其中第一次反应时加入有机酸多元酯。反应结束后用惰性溶剂洗去未负载的四氯化钛,干燥后得到呈粉末状的主催化剂组分。
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The results showed that low temperature, high content of salt and acidic condition inhibited ammonifiers growth, and alkalescent condition showed little effect on ammonifiers. Ammonifying bacteria in Suzhou Creek could not use inorganic nitrogen and carbamide as nitrogen source. Additional carbon source have little effect on ammonifiers growth....
结果表明,低温、高盐度和酸性条件会抑制氨化菌的生长;中、碱性条件下,氨化菌仍能维持正常生长;苏州河的氨化菌无法以无机氮和尿素作为生长所需的氮源;在氮源充足条件下添加额外碳源,对氨化菌的生长无抑制作用;苏州河的环境条件有利于氨化菌的生长。
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The third-stage larvae were developed to fourth-stage larvae (the most optimal develop rate was 41%) when cultured in defined complete medium, further, cultured in defined incomplete medium, was examined no develop and a poorly survival rate. When the third-stage larvae were cultured in the defined complete medium under 37℃ and 5% CO2 in air, the larvae were began to develop to the fourth-stage larvae in cultured for 30 days, being enclosed within the sheaths of the third molts of life cycle.
广东住血线虫的第三期幼虫以MEM medium添加胺基酸、脂肪酸及碳水化合物的培养基在37℃含有5% CO2的无菌培养箱中,培养至第21天已发育至第三期幼虫中期的阶段,第24天已发育至第三期幼虫末期的阶段,第30天开始出现带鞘的第四期幼虫,第36天则观察到虫体明显变长并蜕去外鞘及第三期幼虫特有的眼点消失的第四期幼虫。
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The pH value of silages was all lower than 4.0 and the ratio of ammonia nitrogen to total nitrogen was all lower than 5.0, which improved the quality that all the silages in experiment were good.
经不同切碎方式的各组青贮饲料的有机酸含量均无显著差异(P〉0.05),pH值均在4.0以下,而且氨态氮与总氮的质量比也均在5.0以下,达到了优质青贮饲料的标准,虽然各青贮饲料的粗蛋白、粗灰分和可溶性碳水化合物含量有显著差异(P〈0.05),但均为优质的青贮饲料。
- 推荐网络例句
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The split between the two groups can hardly be papered over.
这两个团体间的分歧难以掩饰。
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This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.
这种做法不仅鼓励了更多的反应,而且减少跟风的可能性。
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The new PS20 solar power tower collected sunlight through mirrors known as "heliostats" to produce steam that is converted into electricity by a turbine in Sanlucar la Mayor, Spain, Wednesday.
聚光:照片上是建在西班牙桑路卡拉马尤城的一座新型PS20塔式太阳能电站。被称为&日光反射装置&的镜子将太阳光反射到主塔,然后用聚集的热量产生蒸汽进而通过涡轮机转化为电力