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Small intestinal biopsies showed subepithelial collagen deposition with varying degrees of villous atrophy and varying numbers of intraepithelial lymphocytes. Four patients had previous biopsies showing enteropathic changes without collagen deposition. Seven cases were associated with collagenous colitis and 1 also had features of lymphocytic colitis. Three patients also had collagen deposition in gastric biopsies. One case was associated with lymphocytic gastritis. Celiac disease (CD, gluten-sensitive enteropathy) was documented in 4 patients. Five patients made a clinical improvement with combinations of a gluten-free diet and immunosuppressive therapy. Two patients died of complications of malnutrition and 1 of another illness. Clonal T-cell populations were identified in 5 of 6 cases tested. Four of these patients improved clinically after treatment but 1 has died. Collagenous sprue evolved on a background of CD in 4 cases. There was no history of CD in others and these cases may be the result of a biologic insult other than gluten sensitivity.

小肠活检表现为上皮下胶原沉积,绒毛萎缩程度不一,上皮内淋巴细胞浸润数量不等。4例患者以往曾做过活检,表现为其他肠病改变,并没有胶原沉积。7例患者合并胶原性结肠炎,且1例还有淋巴细胞性结肠炎的特征。3例患者胃活检也发现有胶原沉积。1例患者合并淋巴细胞性胃炎。4例患者有乳糜泻(CD,谷蛋白敏感性肠病)病史。5例患者经无麸质饮食和免疫抑制治疗后,临床症状有所改善。2例患者因营养不良合并另一种疾病而死亡。6例患者做了T细胞受体基因重排,其中5例发现有克隆性T细胞群,这5例中有4例治疗后临床症状加重,且1例死亡。4例患者在CD的基础上病发胶原性口炎性腹泻;其余患者无CD病史,他们的发病也许是生物源性损害,而非谷蛋白敏感。

The perfect neurosurgery operation anaesth is fast and equability,keep good sedative and analgesia effects,not increase intracranial pressure and cerebral metabolism,no nervous system adverse effects,patients awake fast after use anesthetic,and not excited or psychiatric symptom or respiratory depression or remain drug action.

天津市宁河县医院麻醉科,天津 300060)摘要:理想的神经外科手术麻醉要求诱导过程迅速平稳,维持过程镇静、镇痛好,不增加颅内压和脑代谢,无神经系统不良反应,停药后清醒迅速且无兴奋及精神症状,无呼吸抑制及残余药物作用。

The EAE rats were induced by injecting subcutaneously an emulsion of GPSCH and CFA. In addition, each rat received an intracutaneous injection of pertussis. Albumin in serum and CSF samples was examined on the days of 4,6,8,10,12,14,16,18 and 20 p.i.. The integrity of BBB was assessed by caculating CSF to serum albumin quotient. At the same time the brains, spinal cords, thymus and inguinal lymph nodes were removed for paraffin sections cutting. These sections were used for HE staining and ICAM-1 semiquantitative immunohistochemical staining. The results showed as follows:1. None of EAE rats on days 4,6 and 8 p.i. showed clinical signs whichbecame apparent on day 10 p.i.(2.33±0.76; n=6). On days 12 and 14 p.i.

检测p.i。第4天、6天、8天、10天、12天、14天、16天、18天、20天血清和CSF中ALB含量,其CSF/S ALB比值作为评价BBB损害的指标;同时段取动物脑、脊髓、胸腺和腹股沟淋巴结制成石蜡切片行HE染色和ICAM-1半定量免疫组化分析,结果显示如下: 1、EAE大鼠p.i.4-8天无任何临床表现;p.i.10天症状开始明显,症状评分为2.33±0.76(n=6);p.i.12-14天为发病高峰期,症状评分为3.75±0.54(n=12),病情由最初的活动减少,体重减轻逐渐发展为肢体无力、瘫痪,共济失调,甚至濒死状态;p.i.16天大部分动物症状开始缓解,评分为2.08±0.66(n=6);p.i.20天疾病症状完全消失。

The students with childhood witnessing school violence showed significantly higher scores of psychological symptoms of somatization, obsessiveness, interpersonal sensitivity, depression, anxiety, hostility,phobic anxiety, paranoid ideation and psychoticism, compared with their peers who had no such experience.

与童年期无目睹校园暴力经历的学生相比,有目睹校园暴力经历的女生出现躯体化症状、强迫症状、人际关系敏感、抑郁、焦虑、敌对、恐怖、偏执、精神病性症状等的频率明显偏高,童年期目睹校园暴力经历与女生心理问题明显相关。

The knife was used to cut and strip origin tendon-like fiber of anterior and middle scalene muscle at the point of posterior tubercle of transverse process of cervical vertebra,in which the compress pain was marked.

结果:所有患者均无血肿形成,术后10 min 10例的症状、肌力和感觉明显好转。6个月后随访6例症状消失,肌力、感觉恢复正常,2例有好转,2例无效。4年后仍有7例有效。

Malignant plasmodium was founded in their blood samples.The epidemiological study showed,they had never gone to the higher malaria-epidemic areas in our country,such as Yunnan,Hainan,Guangxi,etc.During living overseas,they were all bitten by mosquito.Three cases were first infected,and others were recrudescence sufferers.When they came to hospital,the temperature was higher than 38.5℃.Except for the clinic symptom such as chill,fever,sweat etc.,five cases emerged tumid spleen and anaemia symptom.

结果〕温州口岸2005年1~7月共发现8例疟疾患者,均为国内人员国外感染,其中男性7例,女性1例,血液涂片均查到恶性疟原虫;流行病学个案调查结果显示,8例患者在国外期间均有蚊虫叮咬史;3例为初发病例,5例为复发病例;8例患者就诊时体温均超过38℃,并出现畏寒、发热、大汗等典型的疟疾临床症状,5例患者出现脾肿大和贫血症状,患者均无并发症状出现。

Results The prevalence rate of urban students was significantly higher than students in rural areas in aspects of respiratory symptoms and respiratory diseases such as cough, expectoration, pharyngalgia, asthma, common cold, rhintis, pharyngitis, tonsillitis, acute bronchitis and so on. However, other respiratory symptoms and disease had no significant difference.

结果 城区学生呼吸系统总症状、咳嗽、咳痰、咽痛、气喘等呼吸道症状,感冒、鼻炎、咽炎、扁桃体炎、急性支气管炎等呼吸系统疾病的检出率均显著高于农村学生(P<0.01或P<0.05);呼吸系其他症状与疾病差异均无统计学意义(P值均>0.05)。

C Severity of psychophysiological symptoms were significantly higher than the patients without psychiatric symptoms.

身心症状之严重度(标准化平均值1.24)在统计上显著高於在过去的研究中无精神症状病人的身心症状(标准化平均值0.39)。

Patients have been cured over the years has proven that:"snore snore quietly," capsule with treating the symptoms, blood pairs of fill, Qi Xie stasis, Tongqiao Xingnao, Qingyan benefit dry, Shugan Qi, lipid-lowering blood pressure, Paul Liver Liver, enhance the effectiveness of functions, enabling the body's "essence, gas, god" full tune up so that the "tired" of the heart and brain, oral cavity and respiratory organs,"refreshed","all in their place,"" responsible for their own,"" harmonization,"return to nature when they are not ill health, and without any toxic side effects (ie: no addiction, no dependency, no pain, no trauma, no adverse reaction).

病人已治愈多年来已证明:&打鼾打鼾地说:&与症状治疗,胶囊剂,血液对填土的契化瘀,通窍醒脑,清咽效益干,疏肝理气,血脂,降低血压,保罗肝肝,提高效率的功能,使人体&的本质,天然气,神&完全调好,使&厌倦了心脏和大脑,口腔和呼吸系统器官&,&刷新&,&在他们的地方,所有的&&为自己负责&,&协调&,回归自然时,没有患病的健康,无任何毒副作用(即:无吸毒,无依赖性,无痛苦,无创伤,无不良反应)。

Lacunar infarction in patients with hypertension is also common cerebrovascular disease, clinical manifestations of light, many people without clinical symptoms, and in nuclear magnetic resonance, CT examination or autopsy, was found when more specific clinical symptoms are: a simple movement obstacles, mild hemiplegia, aphasia or without sensory disturbance; pure sensory disturbance, migraine paresthesia or loss of body; dysphonia - clumsy hand syndrome, manifested as paresis and paralysis of tongue, speaking clearly, swallowing difficulties, fine motor hand and foot less flexible; ataxia and hemiparesis, inability to break limbs and lower limbs than upper limbs, uncoordinated movements, these symptoms often disappear in two weeks.

腔隙性脑梗塞也是高血压患者中常见的脑血管病,临床表现较轻,很多人无临床症状,而在核磁共振,CT检查或尸体解剖时才被发现,较为特殊的临床症状有:单纯运动障碍、轻度偏瘫,不伴失语或感觉障碍;单纯感觉障碍、偏身感觉异常或丧失;发音障碍-手笨拙综合征,表现为轻瘫和舌瘫、说话不清、吞咽困难、手脚精细运动欠灵活;共济失调性轻偏瘫,肢休无力、下肢重于上肢,运动不协调,这些症状常可在2周内消失。

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