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The expression level of metabolitic enzyme (CYP1A1, CYP1B1) and its correlation with cell differentiation /apoptosis were studied as well. The influence of resveratrol in cell cycle was determined with FCM. Results 1 Resveratrol not only suppresses the growth of medulloblastoma cells in a dose and time related fashion but also induces cell differentiation and apoptosis. Resveratrol promotes differention of UW228-1,-2 cells to forward glia, UW228-3 and Med-3 cells to neuron. A treatment of resveratrol in the concentration of 100μM for 48hrs comit most of cells die of apoptosis. 2 Among the four cell lines Fas and Caspase-3 were constantly expessed, whereas FasL was absent irrespective to the drug treatment. 3 ICC, RT-PCR, Western-blot hybridization and EROD enzymatic activity assay demonstrated that expression of CYP1A1 is different after treatment with resveratrol in four cell lines, up-regulated in three UW228 cell lines in a dose dependent manner but down-regulated in Med-3 cells. Suppressive effect of resveratrol on CYP1B1 expression is the same among four medulloblatoma cell lines. 4 Cell cycle distribution of UW228-3 was greatly changed after treatment.

结果:1、白藜芦醇以时间和剂量依赖性方式抑制髓母细胞瘤细胞生长,同时促进细胞的分化和凋亡:白藜芦醇促使UW228-1、-2靶细胞向神经胶质细胞方向成熟分化,UW228-3、Med-3细胞向神经元细胞方向成熟分化,以100μM作用48小时效果显著;2、四个细胞系均有Fas和Caspase-3表达,但无Fas-L基因表达和蛋白活性产生,因此难以形成Fas相关性死亡通路;3、白藜芦醇处理前后CYP1A1基因的表达在各细胞系略有不同:UW228-1,-2,-3三个细胞系白藜芦醇以剂量相关性方式上调CYP1A1的表达,而Med-3细胞系,白藜芦醇却抑制CYP1A1的表达;四个细胞系在白藜芦醇处理后CYP1B1的表达均受到抑制;4、UW228-3细胞系经白藜芦醇作用后细胞周期有较大改变,表现在G0/G1期在整个细胞周期中所占的比例增加,而其它时期则相应减少。

The testing results indicate there is a visible regulating effect in soil temperature with crop residue cover.

试验结果表明,残茬覆盖对土壤温度有明显的调节作用,5、10、15、20 cm各层有覆盖相对于无覆盖分别增温1.5~2.1℃、0.9~1.2℃、0.2~0.9、0.4~0.8℃,随着土壤层的加深,覆盖对土壤温度的调节作用越来越小。4月20日至6月15日前后,随着覆盖量的增加,土壤温度开始升高,但覆盖量增加到一定程度后,土壤温度将下降,在6月20日以后,随着覆盖量的增加,土壤温度逐渐降低,其中30%覆盖相对于无覆盖,降低1.1~1.5℃,50%~80%覆盖降低2~3.6℃,而表土层降低幅度最大,沿深度方向幅度越来越小。

For the principal component, namely the voltage stability analysis function, three kinds of nodal injection power modes are defined, i.e., the random varying direction of load, the response setting direction of generator and the ratio of active power component to reactive power component in load power, and a continuous power flow model that is easy to utilize and comprehend by dispatching center is built, based on this model three kinds of formulae to calculate the sensitivities of loading margin with respect to three kinds of nodal injection power modes are derived respectively, and on this basis the influence of nodal injection power mode on loading margin can be analyzed in order that the voltage collapse can be avoided by fast implementing early warning of voltage stability and adopting effective corrective control.

文章针对N-EMS的主要组成部分--电压稳定分析功能,定义了3类节点注入功率模式:负荷的随机变化方向、发电机的响应设定方向、负荷的有功和无功比例,建立了易于被调度中心运用和理解的连续潮流模型,在此模型基础上分别推导得到负荷裕度对3类模式的灵敏度公式,据此分析节点注入功率模式对负荷裕度的影响,以便能够快速进行电压稳定预警和采取有效的校正控制来避免电压崩溃。

The tailless aircraft is regarded as one of the developing directions of the new type aircrafts.

无尾飞机是新型飞机的发展方向,与传统的飞机相比,其飞行控制系统更为复杂,故障出现的概率也更大,因此重构控制系统是无尾飞机安全飞行的保障。

At last, all related problems due to ship type and towing speed influencing the quality of captured images and results were discussed. A ship model with V-shape bottom and protruding keel might cause some disadvantages for PIV measurements. The use of longer laser light ducts extending deeper is a possible solution. A ship model with light yellow paint will cause the unproportionate of light and will cause white background on captured images. It is suggested to re-paint the ship model in black or dark colors to solve this problem. In high-speed test conditions, a ship model's bow waves entrain large amount of air bubbles into water and those bubbles will block the view of camera causing some random black spots in the images. Thus, it is necessary to remove the useless black spot data and repeat the same test condition if statistics requires enough number of images.

本文讨论建立此系统之技术及实验方法,设备的架置方式和配置为一可调性调整之开放式架构,质点施放方法以一自制的施放架於实验前先布置於测试段中,并制定一实验流程规范,再分别针对实验所得滑航型及排水量型船模的流线方向及切流线方向各不同位置及船速之速度进行流场分析;实验结果发现不同船型会造成不同的实验困难:船形上突起之龙骨及V形船底会遮住照明光线,可利用较深之导管调整光页角度改善;而浅色船模表面会造成光线的不均匀,可以更改船模涂装颜色改善;高速实验的气泡会不定点的遮住光线,须先除去无资料区域并使用更多资料组数来改善。

In this process, the electrolylic bath with cationic exchange membrance and leas electrode is used. The cathode liquor is oxalic acid, the anode liquor is diluted sulfuric acid. The process above has following advantages with high yield, top quality, lower cost, no "three wastes" pollution, and no oxalic aldehyde in the product. It is a cleaner and environment-friend technology, and is a development trend for production of glyoxalic acid. Complete analytical process for raw materials, intermediate and final products were established.

本论文通过对乙醛酸合成路线的研究,确定了草酸电解法制乙醛酸的工艺路线,此法采用装有阳离子交换隔膜和铅电极的电解槽,阴极电解液为草酸溶液,阳极电解液为稀硫酸,该工艺具有产品收率高、质量好、成本低、无三废污染、产品中无乙二醛等特点,是一条清洁、绿色工艺,是生产乙醛酸的主要发展方向。

Based on theories of geometrical optics and electromagnetic wave promulgation, models of three status of aqueous foams transit by light were set up, and the situations of mono- and double- layer unassimilated, assimilated and electric solid infusible materials were investigated for the changes of orientation, path and energy distribution of ray.

基于试验结果,利用几何光学原理和电磁波传播理论,建立了水基泡沫三种状态下的消光模型,通过理论分析和数值模拟,研究了单层界面无吸收、双层界面无吸收、有吸收和含导电性固体不溶物情况下的光线传播规律,从光线传播方向和能量的变化方面,揭示了水基泡沫消光的机理及其对目标探测和甄别的影响。

This paper gives an introduction to the construction technique of Germany Rheda non-gravel trackway whose foundation adopt continuous paving and pouring concrete base and concrete trough by using slip-form paver,Compared with the technique we have used for long time,which is supported by slot-ditch,the new construction technique gives US new thinking and direction on how to enhance mechanized degree and engineering quality.

介绍德国铁路土路基上枕式无碴轨道轨下基础采用滑模摊铺机连续摊铺混凝土底座和混凝土路槽的施工技术,并与我国长期施工实践所积累的较为成熟的轨排支撑架法技术相比较,对如何再提高机械化施工程度以及如何提高施工质量提出新的思路与方向。关键词:滑模摊铺机;枕式无碴轨道;混凝土底座;混凝土路槽

Packages should be placed on their side in the direction of the steam flow, endeavouring to ensure that all the packages are leaning or lying in the same direction to ensure free passage of the sterilant.

因此器械包装的摆放应该根据蒸气的气流方向放置,尽力地保证所有的包装躺或靠着相同的方向,以便灭菌因子能无阻碍地穿透包装。

Chorus oh, you never turned around to see the frowns on the jumpers and the clowns when they did their tricks for you you never understood that it ain't no good you shouldn't let other people get your kicks for you you used to ride on your chrome horse with your diplomat who carried on his shoulder a siamese cat ain't it hard when you discovered that he really wasn't where it's at after he took from you everything he could steal princess on a steeple and all the pretty people they're all drinking, thinking that they've got it made exchanging all precious gifts you better take your diamond ring, you better pawn it babe you used to be so amused at napoleon in rags and the language that he used go to him he calls you, you can't refuse when you ain't got nothing, you got nothing to loose you're invisible now, you've got not secret to conceal Like A Rolling Stone

没了回家的方向、也没人认识像个流浪汉高傲的王子,和所有那些漂亮的人们他们都喝着酒,琢磨着怎么能淘换到更值钱的玩意儿但是你呢,你得把你的钻戒举起来,把它当了人都有倒霉的时候,看着戏里走背字儿的拿破仑你不是曾经还挺得意吗?现在轮到你了,拿破仑在招呼你了,你无路可退了当你一无所有的时候,你不用担心会失去什么了现在你已经透明了,已经没啥可隐瞒的了孤身一人的滋味你觉得怎么样?没了回家的方向、也没人认识像个流浪汉。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。