无影响的

In order to study the relation of cytochrome P-450 with the protective action of SY-801 and SY-640 against 〓-induced UDS and 3H-BP binding to nuclear DNA, the effects of SY-801 and SY-640 on liver microsomal cytochrome P-450 were studied in mice. The results indicated that the liver microsomal cytochrome P-450 concentration and aminopyrine demethylase activity were significantly increased in mice pretreated with SY-801 150mg/kg or SY-640 150 mg/kg once daily for three days.

本实验进而观察了SY-801对小鼠肝微粒体细胞色素P-450酶系的影响，结果表明SY-801和SY-640体内连续给药3天，可诱导小鼠肝微粒体细胞色素P-450含量明显增加，同时氨基比林脱甲基酶活性亦明显增加；给药1次2小时内二者均可抑制氨基比林脱甲基酶活性，而对肝微粒体细胞色素P-450含量则无明显影响。

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis. CA inhibition may not be an important contributor since CA II expression and CA activity was intact in anhidrotic mice treated with topiramate.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

In summary, our results indicate that hypohidrosis is a frequent adverse effect in children with topiramate therapy. Younger age and hot weather rather than drug dosage are independent risk factors for topiramate-associated hypohidrosis. The resultes also rule out the possibility that topiramate act on its known mechanisms of action, such as potentiating GABA activity at GABAA receptors and antagonizing the AMPA/KA subtype of glutamate receptor in the secretory cells of sweat glands to inhibit sweat secretion. Our data also suggest that topiramate impairs sudomotor function in mice and leads to a significant reduction in AQP5 expression in sweat glands of anhidrotic mice, thus raising the possibility that dysregulation of AQP5 may contribute to topiramate related hypohidrosis.

综合全部实验结果，本研究提示：夏季和低龄是托吡酯引起泌汗障碍的主要危险因素，而托吡酯剂量对泌汗(来源：A44B8787C论文网www.abclunwen.com)功能的影响较小；托吡酯可以抑制小鼠汗液的分泌，小鼠的年龄并不影响这种抑制作用，但托吡酯对小鼠体温无明显影响；托吡酯并不是通过对GABAA受体及AMPA和KA两种谷氨酸受体亚型的作用而在汗腺分泌细胞抑制泌汗；托吡酯不影响汗腺形态及Na，K-ATP酶活性；汗腺分泌细胞的AQP5功能失调可能与托吡酯引起的泌汗障碍密切相关，而碳酸酐酶抑制作用并不是泌汗功能损害的主要原因。

But if investors expand their stock holding period to three or six years, the influence of employee bonus on stock returns is uncertain.

但若将股票持有期间拉长至三年或是六年，则员工分红对於投资人股票报酬率的影响则无确定影响。

Neither was the material properties of cortical bone in tibia between the two groups at every stage of experiment.

卵巢切除对皮质骨的影响主要表现在使骨髓腔扩大，对骨外膜的影响较小，在短期内对皮质骨的力学性能无明显影响

The effects of mating experience and temperature on the production of the female black cutworm moth's sex pheromone were studied in this paper. The results indicated that the mating experience did not significantly affect the production of sex pheromone.

中文摘要：研究了交配和温度对小地老虎雌蛾性信息素产生的影响，结果表明，交配对性信息素各组分的滴度无显著影响，因此不影响小地老虎在下一暗期的再次求偶和交配。

The aim of this study was an evaluation of the influence of HiLoon aerobic performance and its physical effects. Elite swimmers、 collegestudents major in physical education and rats were exposed to simulatedaltitude in a decompression chamber and the followings were investigated:(1) erythropoiesis and erythropoietin,(2)maximal oxygen uptake,(3)body weight and body composition,(4)serum parameters of metabolism andhormone,(5)erythropoietin gene expression in kidney and vascularendothelium growth factor gene expression in heart.1 Effects of simulated "living high-training low" on aerobic performancein elite swimmersFourteen swimmers (10 men, 4 women) from Shandong swimming team weredivided into two groups: experimental group (living high-training low,n=8,6men,2women),living at a simulated altitude of 2,800m for 13 to 14 hours per day for 3weeks in a decompression chamber and training at sea level; control group(living low-training low, n=6,4 men,2 women),living and training at sea level.

为系统探讨高住低练对机体有氧能力的影响及其机制，本研究利用低压舱来模拟高原气压条件，分别以优秀游泳运动员、体育专业大学生和大鼠为实验对象，从以下几个方面来初步探讨模拟高住低练对机体的影响：(1)红细胞生成和EPO，(2)最大摄氧量和无氧阈，(3)体重和身体成分，(4)血清物质代谢指标及激素水平，(5)大鼠肾脏EPO和心脏VEGF基因表达。1 模拟高住低练对优秀游泳运动员有氧能力的影响 14名山东省游泳队运动员(男10人，女4人)，随机分为两组：实验组(模拟高住低练组，男6，女2)和对照组(低住低练组，男4，女2)。

The results obtained in the frictionless market are applied to study the effects of incomplete information to portfolios.

信息不仅影响投资者在无风险资产和风险资产之间的资金分配比例，而且影响风险资产组合。

Result:As compared with the model group, the effect of small dose group and middle dose group of osteopractic total flavone on TBV% of shankbone increased significantly; the effect of small dose group and middle dose group of osteopractic total flavone on TRS% of shankbone reduced significantly and TFS%, AFS%, MAR, BFR of shankbone reduced obviously; the effect of middle dose group of osteopractic total flavone on OSW and mAR reduced obviously, the effect of small dose group of osteopractic total flavone on them had the tendency of reducing, but there was no statistical significance.

结果 ：对胫骨骨小梁体积百分比的影响，与模型组比较，骨碎补总黄酮小剂量组和中剂量组的TBV %明显增高；对胫骨骨小梁吸收表面百分比的影响，与模型组比较，骨碎补总黄酮小剂量组、中剂量组的TRS %显著降低；对胫骨骨小梁形成表面百分比，活性生成表面百分比，骨小梁矿化率和骨小梁骨生成率的影响，骨碎补总黄酮小剂量组、中剂量组的TFS %，AFS %，MAR ，BFR较模型组皆明显降低；对胫骨类骨质平均宽度和骨皮质矿化率的影响，骨碎补总黄酮中剂量组的OSW和mAR与模型组比较，明显降低；骨碎补总黄酮小剂量组与之相比，有下降的趋势，但无统计学意义。

If the recruitment system was not complete enough so as to select the competent staff; furthermore, once recruited, better professional training cannot be provided, all these will have significant impacts on their future work execution in law enforcements and criminal fight.

虽然；我国基层警察人员招募考试跟治安维护、犯罪防治，主观上无直接关系，但在客观上却有著间接关系，基层警察为治安侦防第一线工作人员，倘若招募制度未能有著完善的规画机制，以便筛选适任人选，一旦录取后又无良好训练配套措施设计，对於未来执法与治安维护工作良窳有著深远影响。

Plunder melds and run with this jewel!

掠夺melds和运行与此宝石！

My dream is to be a crazy growing tree and extend at the edge between the city and the forest.

此刻，也许正是在通往天国的路上，我体验着这白色的晕旋。